It is all a question of strain. This alpha-synuclein fibril "1B" causes Multiple System Atrophy (MSA) in mice. It resembles parts of the aSyn strain purified from human patients. It is dangerous.

RT @epflSB: Congratulations to Professors Henning Stahlberg (@LabStahlberg), Knut Müller-Caspary (@CeNS_LMU), and Carsten Sachse (@SachseGr….

information can be found at The position is available immediately, funding is available, and the start date is flexible. For questions or additional information, please contact Henning Stahlberg at henning.stahlberg@epfl.ch.

Candidates should have experience in electron microscopy, electron tomography and/or image processing, and be open to support or participate in the development of new technologies at the level of hardware, EM operation, and online data processing.

For this, we develop novel approaches using a 300kV Titan Krios equipped with a cold-FEG, an RF cavity for GHz beam pulsing, a Cs probe corrector, the usual autoloader and Falcon4i, and followed by super-fast hybrid pixel electron detection.

The low signal-to-noise ratio in cryo-EM is limiting its performance. We explore diffractive electron imaging technologies such as Ptychography and other 4D STEM variants to improve resolution and contrast in cryo-EM.

PostDoc, Senior Scientist and/or PhD position in Cryo-EM Method Development in Lausanne. We are looking for a PhD student, PostDoc, or Senior Scientist to join our team to support cryo-EM data collection, using conventional and novel approaches, including diffractive imaging.

The first CryoWriter prototype has arrived, from Cryo-EM grids from nanoliters of sample, vitrified at ultrafast speed, here setup in a BSL-2 facility. We are so much looking forward to playing with this amazing tool.

RT @cryoEM_Papers: cryoWriter: a blotting free cryo-EM preparation system with a climate jet and cover-slip injector .

RT @ShaLGW: Cutting the rug on Lac Léman #DCI22

RT @BolandLab_GE: The Dubochet Center for Imaging. “This was an achievement”.

RT @UTSWBrain: Congratulations to @ShahmoraLab, winner of the @ParkinsonDotOrg "Stanley Fahn Junior Faculty Award." The award will support….

RT @BolandLab_GE: The #cryoEM community is meeting again. Next week the #DCI22 symposium will take place in Geneva & Lausanne followed by t….

RT @BolandLab_GE: #DCI22 . Jacques Dubochet. Video in 🇫🇷.

RT @BolandLab_GE: We expect around >250 participants, with many friends and former colleagues of Jacques. Don’t miss this opportunity to ge….

RT @BolandLab_GE: The #DCI22 symposium will take place in 20 days and you can still join!. Please register here:. T….

Postdoc or senior scientist position available in our group, to develop methods in cryo-EM, using a Cold-FEG Titan Krios with RF-cavity single-electron gun, Cs-probe corrector and Falcon4i & hybrid pixel detector. Contact me offline for more info, or visit

RT @BolandLab_GE: DCI Symposium 2022 #DCI22. The program. All applicant will be informed in the next few days (ASAP, we need to resolve so….