Laguette Lab
@LabLaguette
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Molecular Basis of Inflammation Lab @IGH_MTP @CNRS @UM
Joined December 2020
We are recruiting! Come and join us in sunny Montpellier at @IGMM_Montpel @CNRS_OccitaniE @umontpellier to work on an exciting @ERC_Research funded project! #inflammation #immunology #molecularbiology
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Please RT! We still have #positions open! If you have a strong interest in molecular biology, inflammatory reponses, and metabolic homeostasis: please apply! email interest to: nadine.laguette@igmm.cnrs.fr and/or directly connect to the CNRS recruitment portal!
We are #recruiting! If you are looking for a #postdoc position in the fields of #innateimmunity and #inflammation, contact us! Positions are for a min of 2 years, starting Oct 2023, on the vibrant main @CNRS_OccitaniE campus in Montpellier, within the @IGMM_Montpel - Please RT!
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We are #recruiting! If you are looking for a #postdoc position in the fields of #innateimmunity and #inflammation, contact us! Positions are for a min of 2 years, starting Oct 2023, on the vibrant main @CNRS_OccitaniE campus in Montpellier, within the @IGMM_Montpel - Please RT!
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We are #recruiting! If you are looking for a position in the field of #bioinformatics, please contact us! The position is for up to 5 years, starting October 2023, on the vibrant main @CNRS_OccitaniE campus in Montpellier, within the @IGMM_Montpel - Please RT!
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It's now official, the lab will be moving in coming weeks to a new reasearch environment. @IGMM_Montpel : thank you for welcoming us!
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Announcement!! The lab is soon moving š We also have a few positions to be filled to start new exciting projects. Stay tuned for more news !
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And not to forget our next door neighbours: @IRIM_life : @FabienBlanchet
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Thrilled also to have had the support all accross the ocean from @maraademartino & @CVanpouilleBox from Weill Cornell and Min Sup Song & Mi Kyung Park from MD Anderson.
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Many thanks to our friends: @IRCM_MTP : @NativelCeline & @MaggydelRio for spheroid experiments; @LabSoap: @nbidere @c_maghe @JaneJardine6 & juliegavard and from the IGF in Montpellier (@DonovanPineau & JP Hugnot) for patient cell experiments
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Many thanks to @Azelead_Biotech for the #zebrafish #glioblastoma experiments performed by @JohannaMarines1 under the supervision of @KarimaKissa and twitterless Laura fontenille.
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Bravo @ClaraTaffoni & @JohannaMarines1 ! Special thanks to our many collaborators on this study š¤©. Together, we showed that DNA-PK and cGAS cooperate for optimal nucleic acid-associated inflammatory responses, providing a rationale for cGAS downregulation in early tumorigensis.
Nice way to end 2022! Congrats @ClaraTaffoni, @JohannaMarines1 and our many co-authors! DNA damage repair kinase DNAāPK and cGAS synergize to induce cancerārelated inflammation inĀ glioblastoma
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DNA-PK catalytic activity enables cGAS-dependent cGAMP production. Beautiful collabroative work, led by @ClaraTaffoni and @JohannaMarines1 Check it out: The crosstalk between DNA-PK and cGAS drives tumor immunogenicity
biorxiv.org
Cytosolic DNAs promote inflammatory responses upon detection by the cyclic GMP-AMP (cGAMP) synthase (cGAS). It has been thus suggested that cGAS downregulation is an immune escape strategy harnessed...
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We are currently recruiting a post doctoral fellow (for September 2022. If you have expertise in biochemistry, molecular biology and an interest for the study of innate immune responses - consider applying. To apply, visit the CNRS website (or email me!). RT! @IGH_MTP
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Post doctoral position (H/F) https://t.co/zRFtD30Oaq
#Emploi via @EmploiCnrs Don't hesitate to apply and RT! @IGH_MTP @umontpellier @Occitanie
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NEW ISSUE!: Featuring work from Vila et al. discovering that STING regulates polyunsaturated fatty acid (PUFA) metabolism, and in turn, PUFAs inhibit STING-dependent inflammation. https://t.co/d6exB5BDGd
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Many thanks to all our collaborators on this project!
Congrats to @LabLaguette! STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses https://t.co/uhPSY36LZQ
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Post doc position available. Please feel free to RT in your networks and to potential candidates! #postdoc #position #inflammation #research
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Happy to share our updated manuscript! Sting orchestrates the crosstalk between polyunsaturated fatty acids metabolism and inflammatory responses
biorxiv.org
Inflammatory disorders are major health issues in which immune function and metabolic homeostasis are concertedly altered. Yet, the molecular mechanisms coordinating innate and metabolic pathways in...
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