Karas Lab
@KarasLab
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Synthetic Biology. Designer cells and organelles. Space plants and microbes. Optimization of DNA delivery: conjugation, cell fusion.
London, Ontario
Joined November 2017
Newest preprint from K-lab: Direct Genome Transfer from Acholeplasma laidlawii to Yeast. Congrats to @Daniel_Nucifora Tanveer Saini @SchulichMedDent Thank you for sponsoring this research @NSERC_CRSNG #synbio #GenomeTransfer #SynCell
https://t.co/jOV17jR2nh
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Newest preprint from K-lab: Resolving replication incompatibility between chloroplast and conjugative plasmids in E. coli. Congrats @ejlwalker and all authors. @SchulichMedDent Thank you for sponsoring this research @ARIA_research @NSERC_CRSNG
https://t.co/60LzdDoXed
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Bacterially grown living materials with resistant and on-demand functionality "K. rhaeticus produces a cellulose matrix that encapsulates resistant Bacillus spores, allowing them to germinate and conduct programmable functions under permissive conditions" https://t.co/ywUz61o0BF
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Come back from summer holiday and looking for a new challenge? My lab has one more postdoc position, to work on the assembly of large synthetic chromosomes, in collaboration with @ProfTomEllis and @ceronifranci. Closing in a week, please re-post:
jobs.manchester.ac.uk
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Are you eligible for the NSERC Postdoctoral Fellowships (PDF) program and interested in joining Karas lab? If yes, please send your CV to bkaras@uwo.ca Details & eligibility: https://t.co/cGgjY25XRM
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Happy 94th Birthday Ham!
Today, we celebrate the 93rd Birthday of a fantastic scientist and mentor. Happy Birthday Ham!
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Paper 🚨📢! Adenine methylation in PAM sequence regulates Staph aureus Cas9 activity in bacteria. https://t.co/Zkqa46lMYN. Superstar collab between #DaltonHam @nortnlentivirus
biorxiv.org
Cas9 nucleases are the effectors of the class 2 type II CRISPR system in bacteria and function to restrict invading DNA. They can also be used with single guide RNAs (sgRNAs) as antimicrobials and...
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New paper 📢. What happens when @gary_wfoo genetically entangles a thermally-regulated meganuclease and colE9 immunity protein? Ultra-stable biocontainment in the mammalian gut!!
biorxiv.org
Imbalances in the mammalian gut are associated with acute and chronic conditions, and using engineered probiotic strains to deliver synthetic constructs to treat them is a promising strategy....
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Today, my postdoc @algaladvocate has been awarded the University of Manchester’s Bicentenary Fellowship and will soon be starting his own lab. He is the eighth independent PI to emerge from my lab in the past seven years. Proud PI moment.
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We're hiring for 2 postdocs to work in our lab in London on the newly announced Wellcome Trust SynHG project. If you know people looking to work on big-scale ambitious science like this, please RT and share this with them. Apply by 7/20, interviews in Aug. https://t.co/TOVjZ3osO5
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Another bid day in K-lab. Congrats Jack Huang on successfully defending Master thesis and getting into Medical School at University of Toronto! 🎉 @westernuBiochem @SchulichMedDent
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What if crops could grow in poor soil, resist disease and carry more nutrients? At #SchulichMedDent, @KarasLab is building synthetic plant genomes to make that future possible, with support from the U.K.’s @ARIA_research.
schulich.uwo.ca
Bogumil Karas, PhD, was awarded $1.5 million to optimize plants by creating genomes from scratch.
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Excited to share that our lab is part of the @ARIA_uk Programmable Plants initiative! @WesternU @SchulichMedDent @westernuBiochem
The nine teams we’re funding in Synthetic Plants are paving the way for more productive, resilient, and sustainable plants.🌱 Discover how they'll deliver growth in agriculture for the UK + beyond: https://t.co/NlFGpF0aio
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