Karim Beguir
@kbeguir
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Co-Founder & CEO @instadeepai Entrepreneur passionate about developing the ML community. @Google For Startups Mentor, @DeepIndaba Steering Committee Member
London UK
Joined November 2011
Wow we made the cover of Nature Machine Intelligence @NatMachIntell for the first time! 🥇🚀 ChatNT, our conversational agent for genomics, literally allows you to speak to a dna sequence 🧬 Very proud of the @instadeepai dream team for this historical milestone! ✨
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From our 1st NeurIPS Oral to advances in Biology (like NTv3) & PCB optimization, @instadeepai had its best AI innovation year EVER!🥇Incredibly proud of our team delivering real-world impact in Life Sciences and Industrial AI. Wishing you all a happy new year 2026! 🎉✨
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Our NTv3 genomics foundation model is live! 🎉 With now a 1 million nucleotide context window and cutting-edge performance, this is truly remarkable work from @instadeepai. Well done @deAlmeida_BP & team! 💥🚀👍🏼
🚀 Introducing Nucleotide Transformer v3 (NTv3) Today, we are very excited to share our latest foundation model for biology - Nucleotide Transformer v3 (NTv3). NTv3 is @instadeepai new multi-species genomics foundation model, designed for 1 Mb, single-nucleotide-resolution
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Ilya rarely goes public and usually there’s a clear message when he does! Hopefully big news on the alignment front from AI’s top researcher! 🙏🏻
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How can AI responsibly transform industrial operations? Join @kbeguir alongside @DellTech, @ST_World & @Artefact_Global at #AdoptAI in Paris this week! 🇫🇷 🎯 Move AI to the Shopfloor for Responsible Industry 🗓️ 26 November, 9:36–10:00 | Grand Palais, Paris 🧵⬇️
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Basically reframing RL reward hacking by adding just one sentence 😮 completely stopped the emergence of dangerous, misaligned behavior. Awesome work from @AnthropicAI! 👏🏼
New Anthropic research: Natural emergent misalignment from reward hacking in production RL. “Reward hacking” is where models learn to cheat on tasks they’re given during training. Our new study finds that the consequences of reward hacking, if unmitigated, can be very serious.
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This is real signal. Beyond impressive! 🤯
Gemini 3 models from @Google @GoogleDeepMind have made a significant 2X SOTA jump on ARC-AGI-2 (Semi-Private Eval) Gemini 3 Pro: 31.11%, $0.81/task Gemini 3 Deep Think (Preview): 45.14%, $77.16/task
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As seen in @NatureMethods, meet SegmentNT, our transformer model for fast, single-nucleotide, multi-task genome annotation. 🧬
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🔍 To learn more: 👉 Nature Methods: https://t.co/jIuotb4ofU 📖 Blog: https://t.co/i7Sf1WBHBX 📄 Paper:
biorxiv.org
Genome annotation models that directly analyze DNA sequences are indispensable for modern biological research, enabling rapid and accurate identification of genes and other functional elements. This...
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I'm super pleased to share that SegmentNT, our single-nucleotide resolution genome annotation model, has been featured in Nature Methods! 🚀 SegmentNT builds on our Nucleotide Transformer foundation model to deliver on the ultimate task: single-nucleotide resolution
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✅ That’s a wrap on PCBWest 2025! ♥️ We loved meeting so many brilliant minds & showcasing what DeepPCB can bring to the table. 💫 Highlights: 1️⃣ In-booth demos & live feedback 2️⃣ Strategic chats with engineers 3️⃣ Fresh inspiration to drive our next features 🙌 4️⃣ And last but
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InstaDeep now in Australia! 🇦🇺👍🏼
We wrapped up our first event in Australia at Future Warehouse & Logistics 2025 in Melbourne! It was a great opportunity to showcase @DeepPack, our AI-powered 3D packing software, and to connect with logistics leaders across the region. 🇦🇺
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Hear Alex Graves tell the story behind Bayesian Flow Networks, over a decade in the making. 🚀 In Episode 1 of our new Let’s Talk Research podcast, Alex shares the inspiration behind BFNs and how he sees them evolving. 🧵
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Senior Staff Research Scientist, Alex Graves, re-introduces Bayesian Flow Networks in his first-ever blog for InstaDeep, taking us behind the scenes of their origin story and applications for biology. 🧵
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🎙️ In the latest episode of the #BehindTheGenes podcast, @KBeguir tells the story of InstaDeep's collaboration with @GenomicsEngland and how cross-sector partnership can help drive responsible use of AI in genomic innovation. Listen now on your podcast app on the link below! 🧵
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AI meets PCB design. ⚡️ @instadeepai CEO @kbeguir joined @DanielNenni on @SemiWiki to share how @DeepPCB is transforming placement & routing with reinforcement learning. Faster cycles, cleaner layouts, smarter design.
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We're heading to Kigali for @DeepIndaba! From 17-22 August, Africa’s AI community gathers again at the University of Rwanda for a week of ideas, exchange & impact. 🌍🚀 See you at #DLI2025!
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"The industrial sector, whether it's manufacturing, whether it's hardware design or whether it's logistics, that's a sector which I think is ripe for disruption by AI". Hear @kbeguir's thoughts on a changing industry, and the InstaDeep innovations making transformative impacts.
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Don't miss the latest episode of the @NatureBiotech Forum podcast, featuring InstaDeep Team member and Genomics AI expert Marie Lopez! Join Marie for a discussion on the latest advancements in biotech, covering Genomics AI, DNA Foundational Models, DNA LLM's and much more. 🧬
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