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Dwarkesh Patel Profile
Dwarkesh Patel

@dwarkesh_sp

Followers
126K
Following
45K
Media
832
Statuses
6K

Host of @dwarkeshpodcast https://t.co/3SXlu7fy6N https://t.co/4DPAxODFYi https://t.co/hQfIWdM1Un

San Francisco
Joined December 2019
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@dwarkesh_sp
Dwarkesh Patel
3 months
New blog post where I explain why I disagree with this, and why I have slightly longer timelines to AGI than many of my guests. I think continual learning is a huge bottleneck to the usefulness of these models, and extended computer use may take years to sort out. L-nk below.
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@dwarkesh_sp
Dwarkesh Patel
3 months
"Even if AI progress totally stalls, it's sufficiently easy to collect data on all these different white collar job tasks that we should expect to see them automated within the next 5 years."
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@dwarkesh_sp
Dwarkesh Patel
23 hours
RT @jacobkimmel: .@dwarkesh_sp has a rare talent for traversing the tree of ideas by stepping upon only the most entropic branches. it was….
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@grok
Grok
3 days
Join millions who have switched to Grok.
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@dwarkesh_sp
Dwarkesh Patel
1 day
Why didn't humans evolve our own antibiotics?. I asked @jacobkimmel (full episode is out):
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@dwarkesh_sp
Dwarkesh Patel
1 day
.@jacobkimmel thinks he can find the transcription factors necessary to reverse aging. 0:00:00 – Three reasons evolution didn't optimize for longevity.0:12:48 – Why didn't humans evolve their own antibiotics?.0:26:08 – De-aging cells via epigenetic reprogramming.0:45:24 – Viral
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@dwarkesh_sp
Dwarkesh Patel
1 day
RT @byersblake: You will definitely want to tune into this pod with my cofounder @jacobkimmel and my favorite podcaster @dwarkesh_sp. Jacob….
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@dwarkesh_sp
Dwarkesh Patel
2 days
"Transcription factors allow a very small number of base pair edits at the substrate of the genome to lead to very large phenotypic differences. If you think about how attention works - queries, keys, values - transcription factors are the queries, the genome sequences they bind
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@dwarkesh_sp
Dwarkesh Patel
2 days
I had no idea that humans lost our natural defense against HIV to fight an even worse retrovirus that no longer exists. Old world monkeys still have this immunity - we share the same gene (Trim5-α) - but ours was repurposed millions of years ago. Ep w @jacobkimmel out tomorrow
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@CPAC
CPAC
9 days
Zohran Mamdani: He votes for activists, not you
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@dwarkesh_sp
Dwarkesh Patel
2 days
RT @jacobkimmel: improving biology that evolution has optimized is absurdly difficult. one reason for optimism in longevity is that evolut….
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@dwarkesh_sp
Dwarkesh Patel
3 days
RT @Lewis_Bollard: We did it! Dwarkesh's fundraiser raised $2M+ for high impact work to end the worst abuses of factory farming. I'm so gr….
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@dwarkesh_sp
Dwarkesh Patel
3 days
We’ve raised $2,027,084 for @farmkind_giving (with matching). This will improve the lives of over 20 million animals. We’ve increased the global funding for farmed animal welfare by 1%. That’s crazy - the world is really big place!. Thank you all so much for the incredible
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@dwarkesh_sp
Dwarkesh Patel
8 days
A group of generous donors have pledged to match ANOTHER $500,000 of donations for @farmkind_giving. Huge thanks to:. @seemaychou & @JedMcCaleb: $250,000.@gauravkapadia: $100,000.@ArielNessel: $50,000 (2nd donation).@tylermaule: $50,000.The Dahna Foundation: $50,000. If we
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@dwarkesh_sp
Dwarkesh Patel
3 days
.@jacobkimmel thinks that the functionality to reverse aging already exists in our epigenome. But then why didn't evolution already optimize for longevity? . Jacob explains that if you consider evolution as an optimizer, the gradients flow in a really surprising way. Naively,
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@dwarkesh_sp
Dwarkesh Patel
4 days
RT @dwarkeshpodcast: Casey Handmer argues that investment in natural gas is doomed, even if there were no near-term geopolitical or financi….
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@dwarkesh_sp
Dwarkesh Patel
4 days
RT @dwarkeshpodcast: Casey Handmer argues AI pricing is so elastic that Anthropic could raise subscription prices 10x to fund new gas turb….
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@dwarkesh_sp
Dwarkesh Patel
6 days
RT @pseudoerasmus: From the transcripts of the @dwarkesh_sp podcast with geneticist David Reich. Is it possible that events like the Blac….
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@dwarkesh_sp
Dwarkesh Patel
7 days
China produces 20x+ as much solar as the U.S. (over 1 TW vs. just 50 GW). If solar is the only scalable way to meet the 100s of GWs of extra demand we'll have because of AI, what exactly is the story of how America wins AI?. Is China privileged in the long timelines world? SMIC
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@barstoolsports
Barstool Sports
1 day
RT @PardonMyTake: Tuesday night max woke Big Cat up with a flashlight at 2am because he thought we were going to get sued. @forthepeople ht….
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@dwarkesh_sp
Dwarkesh Patel
7 days
"It's still extremely early. We’re still in the Apple II computer era of solar. Conventional wisdom is that solar demand is going to saturate this week. We've got a graph here somewhere that's like, 'This year is it, it's never going to grow anymore.' Instead, it's just blasting
@patrickc
Patrick Collison
2 years
Solar deployment is now happening at a roughly $500B annualized rate. Which technology deployments were larger than this? The US's aircraft production during WWII seems to have peaked at maybe $400B (inflation-adjusted). Global datacenter construction appears to be maybe
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@dwarkesh_sp
Dwarkesh Patel
7 days
.@CJHandmer on how to feed the AIs. 0:00:00 – Why doesn’t China win by default.0:08:28 – Why hyperscalers choose natural gas over solar.0:18:01 – Solar's astonishing learning rates.0:27:02 – How to build 50,000 acre solar-powered data centers.0:40:24 – Environmental regulations
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@dwarkesh_sp
Dwarkesh Patel
7 days
RT @Lewis_Bollard: Dwarkesh's factory farming fundraiser has now raised $1.7M! That includes ~100 people giving $1K+. Huge props to the m….
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@dwarkesh_sp
Dwarkesh Patel
7 days
As measured by GDP, AI will be super undervalued. How would the datacenter of geniuses show up in GDP? . GDP would show raw inputs (aka chip & energy), and raw outputs (aka cost of tokens). But wouldn't clearly reflect the value of the crazy new shit that's being cooked up in
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@dwarkesh_sp
Dwarkesh Patel
8 days
RT @AlexandraBalwit: It isn't too late to take part in this incredible fundraising effort.* Such incredible momentum. @dwarkesh_sp is a rea….
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