Some say that being a physician-scientist is like wearing two hats. I think it lets me #sockittokidneydisease in two different ways. One foot is in the clinic, helping patients get the best treatments. The other is in the lab, trying to make those treatments better.

RT @OligoclonalBand: I am honored and thrilled to take this next step, and hope to live up to the impressive leadership of my mentors Roger….

RT @KidneyWars: Are you ready for @VCU_Nephrology MS2 Renal meme competition? @MemesNephro @VCUIMClerkship @VCU_IMRes .1. 'Fall's formula'….

RT @DGlaucomflecken: I truly do not think anybody loves the organ they specialize in more than nephrologists love the kidney.

RT @DCharytan: A little piece of history-⁦l from @NYUnephro⁩ Homer Smith’s PH meter -probably the most significant PH meter in neph history….

RT @brendonneuen: "We do much more complicated things, we use much more dangerous drugs for other conditions that don't deliver like this"….

RT @NephJC: Let’s make the @ISNkidneycare campaign #KidneyHealth a global priority a success! . #NephJC #KidneyWk.

RT @Ricky_Turgeon: Since we'll likely never get an RCT of different medication sequencing strategies (what to start/titrate when) for HF wi….

RT @PracheeAC: I also left mid-career during an exciting moment (I’d just moved the lab and was just ramping up in a stimulating new enviro….

RT @GbadegesinLab: Big congrats #H3AfricaKDRN consortium for this landmark paper Take home message APOL1 HR genoty….

RT @AnnaGaddy: 😍it’s true!!! Thank you for being here!! The future is so bright #KidneyWk.

And all the secondary outcomes are in favor of SGLT2i! .Is this a huge enough trial to prove this is 100% effective? No, we’re still going to wait for renal lifecycles. But is it strong data that Sglt2s don’t accelerate progression and might help? .Yes! #flozinate #kidneywk.

At baseline, both groups had fairly high UACr, ~700 mg/g, an average eGFR 19. Slopes of both groups slowed after enrollment (?regression to mean), and slowed more for SGLT2! #kidneywk

Included patients with GFR 10-30, and loss of >2.5 ml/min per year, randomized 2:1. Also included low protein diet as part of standard of care in both groups .Followed total eGFR slope as primary outcome.#kidneywk.How much acute cr rise did they allow before stopping the sglt2?.

DAPA-advKD trialing the initiation of SGLT2i in CKD4 and CKD5!.The next frontier of #flozination. #kidneywk.

Thanks @jaykoyner for this great slide. The figure is key. #kidneywk.

@Nester1Carla @KatherineTuttl8 @FreelyFiltered @VladoPerkovic @brendonneuen This figure will always make me smile; semaglutide saves kidneys. Subgroup analyses show no heterogeneity by GFR or albuminuria. #kidneywk

@Nester1Carla FLOW outcomes by CKD stage are being reported by @KatherineTuttl8 .Gotta plug the great @FreelyFiltered episode with @VladoPerkovic and @brendonneuen #kidneywk.

@Nester1Carla Huge proteinuria reduction—by 2/3!.In every subgroup!.Secondary outcome of eGFR change showed stabilization of GFR, and repeat biopsies showed reduction in C3c staining. #kidneywk

Pegcetacoplan, an inhibitor of c3 and c3b (resulting in c3 and c5 convertase inhibition) in C3GN and immune complex MPGN @Nester1Carla .Included Peds (age 12+) and post transplant!.>1g proteinuria, >30 gfr.#kidneywk.