Fun cell reprogramming discussion with @teleodaniel @EricDai_BioE and @JanineSengstack

In today's episode of the Free Radicals podcast, @EricDai_BioE and I hosted Dr. @JanineSengstack & @robcahill10 , co-founders of @junevity . They are on a mission to extend lifespan and healthspan by combining AI and large scale omics data with genetic medicines known as

Targeting clinical trials in metabolic dysfunction in 2026, gene-silencing approach seeks to reprogram diseased cells to a healthy state. https://t.co/esaatA1gXb #longevity #investment #siRNA #biotech #reprogramming

https://t.co/H7wTl4LMZ1

We’re excited to announce expanded Seed funding. This will help us advance JUN_01 through IND-enabling studies and into the clinic for type 2 diabetes and obesity. This could be the first siRNA cell reprogramming candidate brought to human trials. JUN_01 has demonstrated robust

Longevity biotech is gearing up to deliver medicines that will capture the world’s imagination Thanks to @Stifel for including @junevity as a leader in cell reprogramming

https://t.co/bh4kF7yePJ

𝗡𝗘𝗪 𝗜𝗡 𝗚𝗘𝗡: Junevity co-founders @JanineSengstack & @robcahill10 share a foundational perspective on why transcription factors, once dismissed as “undruggable” and “too risky,” are now within reach thanks to advances in siRNA, omics, and AI/ML. @GENbio

I'm hiring a Bioinformatics Data Scientist at @junevity to develop new therapeutics for longevity-related diseases. Reach out if you like transcription factors, building new ML pipelines for bio, and longer/healthier lives.

For example, see their @PNASNews paper from 2024:

Good review on robustness testing for biomedical foundation models, led by Rui Patrick Xian and @junevity advisor @Reza_Abbassi. Patrick and Reza were collaborators with our co-founder @robcahill10 at UCSF on stability-driven machine learning models for transcriptomic data.

Read Mike Hollan's profile on her leadership style, the @junevity Outlier Culture, and our driving mission to extend healthspan and lifespan by resetting cell health:

Congrats to our Co-Founder & CSO @JanineSengstack , who is featured as one of the @PharmExec 2025 Emerging Pharma Leaders – and on the cover, no less!

Learn more on @junevity from @LongevityTech:

Our @JanineSengstack is bringing the dream to reality

The Junevity RESET platform is the first to identify drug targets to reset cell health using human data, AI/ML and siRNA.

This is personal to me. Five years ago, my mom fell and broke her hip. Before that, my godfather and aunt were both diagnosed with Parkinson’s. In 2020 I decided to go all in on finding new treatments for aging. I studied bioinformatics at @JohnsHopkins , did mouse brain

Junevity emerges with $10m to ‘reset’ cells to a healthy state #longevity #investment #healthspan #biotech #reprogramming https://t.co/HTvYrptRph

Check out an exclusive look at what we're building @junevity covered by @endpts @RLCscienceboss –– we're creating therapeutics for longer lifespan and healthspan by resetting cell health

This week on A4LI’s Scientist Spotlight, we are pleased to be joined by Dr. Janine Sengstack, the Co-Founder and CEO of Junevity. In this episode, we go over @JanineSengstack's scientific journey, from what sparked her initial interest in pursuing science to how her PhD work