Jun
@Jun91487218
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Postdoc Associate @DukeMGM, Interested in fungal (epi)genetics, DNA repair and CRISPR. Alum of @kstate @1decook lab & @FAFU---Views are mine
Manhattan, KS
Joined April 2016
A nice gift for Thanksgiving😀. Our efforts to study the variation in DNA repair outcomes due to distinct repair mechanisms following CRISPR targeting of different loci in Magnaporthe oryzae has been published @NatureComms .(🧵 1/10).
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RT @YufengFang: Thrilled to begin my journey as an Assistant Professor in @OSUPlantPath at @OhioState. Grateful to my mentors @DukeHeitman,….
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RT @Carlos_parq: 🚨 New paper in @NatureComms . After a constructive and rewarding peer-review process (huge thanks to our editors and revi….
nature.com
Nature Communications - Epimutations mediated by RNA interference can confer antifungal drug resistance and affect virulence in fungi. Here, the authors show that these epigenetic modifications can...
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RT @MishDivya: 🌿 Interested in plant science?.🔥 Our lab at NIPGR has 1 PhD position open to study the dynamic behaviour of high temperature….
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RT @brfootball: Over 450 career goals. Cup final heartbreaks. Second place disappointments. And now Harry Kane finally has a trophy for hi….
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RT @MishDivya: New PI alert: Happy to share that I have received the Prime Minister-ECR grant from @ANRFIndia. Thank you @IndiaDST and @NIP….
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RT @VirusesImmunity: NIH indirect costs fund the backbone of research: maintaining labs, ensuring safety, and supporting admin work. These….
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RT @Team_Thomma: 📣New year, new @biorxivpreprint 🎉! A study led by the brilliant @YukiyoSato3 showing that Starship giant transposons domin….
biorxiv.org
Starships form a recently discovered superfamily of giant transposons in Pezizomycotina fungi, implicated in mediating horizontal transfer of diverse cargo genes between fungal genomes. Their elusive...
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Highly dynamic supernumerary mini-chromosomes in a Magnaporthe oryzae strain
biorxiv.org
Magnaporthe oryzae (syn. Pyricularia oryzae ), the causative agent of devastating crop diseases, exhibits remarkable genomic plasticity that contributes to its adaptability and pathogenicity....
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RT @jmuiuc: A troubling incident unfolded at #NeurIPS2024, where a keynote speaker used a slide that perpetuated harmful stereotypes and ra….
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RT @DukeHeitman: In the latest @PNASNews , we discovered that RNAi-loss is more common than expected in the global population of Cryptococc….
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Excited to share our latest discovery on distinct evolutionary trajectories following RNAi loss in Cryptococcus, now published in @PNASNews! Huge thanks to @Cojola429, @VikasYadavSci, @magwenelab, @DukeHeitman and everyone who supported this work!
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RT @michaelkosicki: Updated manuscript! We analyzed Cas9-generated indels at >2,800 synthetic Cas9 targets in 18 DNA repair deficient stem….
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RT @DukeMedSchool: Joseph Heitman, MD, PhD, James B. Duke Professor and chair of the Department of Molecular Genetics and Microbiology, has….
medschool.duke.edu
Joseph Heitman, MD, PhD, James B. Duke Professor and chair of the Department of Molecular Genetics and Microbiology, has been elected to the U.S. National Academy of Medicine (NAM).
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RT @Carlos_parq: Check out our latest preprint on RNAi epimutations!🧬Our team has shown how spontaneous RNAi-based….
biorxiv.org
Epimutations modify gene expression and lead to phenotypic variation while the encoding DNA sequence remains unchanged. Epimutations mediated by RNA interference (RNAi) and/or chromatin modifications...
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RT @KamounLab: I just published: Death by statistics — When one replicate is enough. This week, I committed statistical blasphemy by arguin….
link.medium.com
This week, I committed statistical blasphemy by arguing that, in some cases, one replicate can be enough for a specific type of molecular…
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Structure-guided design, synthesis, and characterization of C22- and C32-modified FK520 analogs with enhanced activity against human pathogenic fungi
biorxiv.org
Invasive fungal infections are a leading cause of death worldwide. Translating molecular insights into clinical benefits is challenging because fungal pathogens and their hosts share similar eukary...
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RT @SamanthaBRegan: Excited to share our preprint of my PhD work in the Jasin lab @MSKCancerCenter! We find that CRISPR Cas9-induced DNA do….
biorxiv.org
Harnessing DNA double-strand breaks (DSBs) is a powerful approach for gene editing, but it may provoke loss of heterozygosity (LOH), which predisposes to tumorigenesis. To interrogate this risk, we...
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RT @biorxiv_genomic: Transposable elements are prevalent vectors of transgenerational epigenetic inheritance in nature .
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