Julia Ritterhoff
@JuliaRitterhoff
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Heidelberg, Germany
Joined December 2019
BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2025 #NobelPrize in Chemistry to Susumu Kitagawa, Richard Robson and Omar M. Yaghi “for the development of metal–organic frameworks.”
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BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2025 #NobelPrize in Physics to John Clarke, Michel H. Devoret and John M. Martinis “for the discovery of macroscopic quantum mechanical tunnelling and energy quantisation in an electric circuit.”
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BREAKING NEWS The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”
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🚨New paper out in Circ Res! Congrats to 1st author DR @OmarBritoStrada & the team👏🏼Here we show DWORF gene therapy boosts cardiac calcium handling, enhances mitochondrial energetics, & protects against heart failure progression🫀💪🏼 Read it here 😍👇🏼 https://t.co/0Jj7M1ydfL
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Mark your calendars! The Institute for Cardiomyopathies Heidelberg is hosting the 10th Anniversary Symposium on 10–11 Oct 2025 in Heidelberg, Germany. https://t.co/AnDz82D37k
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1,2 Millionen Euro Förderung für die Herstellung von „Gen-Taxis“ https://t.co/iLBprahOLV
klinikum.uni-heidelberg.de
Die Dietmar Hopp Stiftung unterstützt den Aufbau einer experimentellen Produktionseinheit für Gentherapien des Herzens an der Medizinischen Fakultät Heidelberg der Universität Heidelberg, in der...
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Are you on the hunt for a novel AAV vector for cardiac gene therapy? We identified a promising candidate in human heart biopsies. @dzhk_germany @uniklinik_hd @CircAHA
https://t.co/55d39nTdSE
ahajournals.org
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Excited to share our latest work on cardiac gene therapy, where we show that AAV5 is effective in delivering S100A1 to the post-ischemic heart, achieving lasting improvement in cardiac performance. Congrats to Doro and the whole team! @dzhk_germany
https://t.co/xHHkWmqGZa
ahajournals.org
BACKGROUND: Guided by long-term safety data for AAV5 (adeno-associated virus 5) in humans, our translational study investigated whether AAV5 effectively delivers genes to healthy and achieves...
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Linker oder rechter Arm? Eine neue Studie zeigt, warum die Impfstelle wichtig ist Bei Impfstoffen kann es einen Unterschied hinsichtlich ihrer Wirksamkeit machen, wo sie in Ihren Körper gelangen. Wissenschaftler in Sydney haben herausgefunden, dass eine Auffrischungsimpfung im…
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Out today from @ThePerryLab, our work suggesting how exposure to high fructose in pregnant mice or developing neonates directly affects neurodevelopment. In @Nature
https://t.co/JsTjic5HLO
@MSKCancerCenter @WeillCornell funded by @NIH @NIH_CommonFund cc: @NIHDirector_Jay
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@CircRes Interorgan Crosstalk in #HF & #Cardiometabolic Diseases Compendium CV, #Kidney, #Liver, & Metabolic Interactions in #HF: Breaking Down Silos https://t.co/IoHHcQscCw by @rsyf2 @josephahill @FaiezZANNAD @ShahzebKhanMD @JenHoCardiology @leahkosyakovsky et al
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Breaking News: A baby with a rare disorder made medical history by receiving the first custom gene-editing treatment. The technique used has the potential to help people with thousands of other uncommon genetic diseases.
nytimes.com
The technique used on a 9½-month-old boy with a rare condition has the potential to help people with thousands of other uncommon genetic diseases.
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Female cardiomyocytes show higher expression of fatty acid oxidation genes, leading to greater reliance on fat for energy. A key insight into cardiac sex differences! @yoshiko96821 @MayaTalukdar
https://t.co/NOV64I8IBL
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#ICYMI: S100A1ct peptide therapeutic against heart failure @JuliaRitterhoff @DZHK_germany
@uniklinik_hd @volkersmirko @wallyjoe33
@Rebecca_Wade_c
@LukasJarosch_
S100A1ct, a synthetic peptide targeting SERCA2a and RyR2, enhances cardiac performance and reduces arrhythmias in preclinical heart failure models. @volkersmirko @wallyjoe33 @Rebecca_Wade_c @LukasJarosch_
https://t.co/R4jJotoku0
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Differences in how male and female cardiomyocytes generate energy may contribute to observed differences in heart disease. New findings from the Page lab: https://t.co/spfdZrLTo8
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We've been busy this year... It's great to see this published! Using 13C-FA tracing in proliferating cells, we observe a robust incorporation into TCA intermediates, which is quiet different from Seahorse analysis. https://t.co/YZlKh7iGyN
journals.physiology.org
The TCA cycle serves as a central hub to balance catabolic and anabolic needs of the cell, where carbon moieties can either contribute to oxidative metabolism or support biosynthetic reactions. This...
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S100A1ct, a synthetic peptide targeting SERCA2a and RyR2, enhances cardiac performance and reduces arrhythmias in preclinical heart failure models. @volkersmirko @wallyjoe33 @Rebecca_Wade_c @LukasJarosch_
https://t.co/R4jJotoku0
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Is basic science undervalued? David Glanzman talks about the decline of 'middle class' labs and that "there is no empirical evidence that the translational approach accomplishes [cures] any better than the traditional one. Claims to the contrary at this point are mere propaganda”
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Happy to share our work on the development of S100A1ct, a peptide based therapy for the treatment of HF. Great collaborative effort! @DZHK_germany @uniklinik_hd
https://t.co/mkqXEZ4E79
ahajournals.org
BACKGROUND: The EF-hand Ca2+ sensor protein S100A1 has been identified as a molecular regulator and enhancer of cardiac performance. The ability of S100A1 to recognize and modulate the activity of...
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