Joo-Hyeon Lee Lab
@JooHyeonLeeLab
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Principal Investigator @SCICambridge
Cambridge, UK
Joined February 2021
Beautiful works from Rawlins lab! Congrats Kyungtae!!! Acquisition of alveolar fate and differentiation competence by human fetal lung epithelial progenitor cells
biorxiv.org
Variation in lung alveolar development is strongly linked to disease susceptibility. However, the cellular and molecular mechanisms underlying alveolar development are difficult to study in humans....
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Very excited to share our recent preprint showing how airway secretory cells contribute to alveolar regeneration using new mouse/human lung organoid and R2Onco systems. Congrats @Jin_fwpd1980, Yujin, @cathdabs, @KvEvans91! Thanks to Kim and @koo_lab
https://t.co/ZuQn5eJL7t
biorxiv.org
While the acquisition of cellular plasticity in adult stem cells is essential for rapid regeneration after tissue injury, little is known about the underlying molecular mechanisms governing this...
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Really excited our paper is now out in @nature! Red2Onco was developed to study how the presence of mutated cells affects their neighbours and microenvironment. @JooHyeonLeeLab, @koo_lab and Simons lab.
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This chapter reviews our current understanding of stem cells of mouse brochiolar airways and their contribution to epithelial maintenance and repair after injury. @cathdabs @Manav_Gupta17 @CarlaKimLab @JooHyeonLeeLab
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Upsizing and Shaping #airway #organoids, our article with @JooHyeonLeeLab is now available in the Health, Medical and Life Sciences virtual issue of Advanced Science #biofabrication #OAUnitedKingdom @wileyinresearch @Corrado___M @cathdabs
https://t.co/6nIKuQGXIf
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We've developed an #organoid culture of human alveolar type II cells and used it to study #SARSCoV2. Congratulations @KvEvans91 on your first paper!
Our latest (and my first) research paper from the Lee Lab @SCICambridge is now available in the December issue of @CellStemCell. Such a great project to work on! #SARS_CoV_2 #COVID19 #lung #minilungs
https://t.co/rPyNl3UtAv
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Check out our latest publication with @Biointerface_CU detailing #organoid up-sizing
A way to 'up-size' the #miniorgans used in #medicalresearch has been developed by a team of scientists and engineers. It's sort of a cross between baking a cake and blowing giant soap bubbles: https://t.co/EojefzyXps
@Biointerface_CU @SCICambridge @Cambridge_Eng @DeptofPhysics
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Excited to share this work by my talented postdoc @Jin_fwpd1980 showing a new cell state in the repairing #lung
Very happy to share our story about AT2 cell reprogramming during lung regeneration. Really appreciate Joo-Hyeon Lee, Lab members @SCICambridge ,and collaborators ( BK Koo @IMBA_Vienna, Georgia and @HanNamshik @TheMilnerInst). Special thank to Emma and members @LabRawlins.
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