Joe Frost
@JoeNFrost
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Postdoctoral immunologist @sloan_kettering Tregs and inflammation // previously iron and immunity @Drakesmith_Lab @MRC_HIU @UniofOxford
Joined September 2020
1/ I’m hugely excited to be able to share with you our paper ‘hepcidin-mediated hypoferremia disrupts immune responses to vaccination and infection’ @MedCellPress . Thank you @Drakesmith_Lab @MRC_HIU @MRC_WIMM + our global collaborators! #Tweetorial time:.
cell.com
Iron deficiency is very common in humans and animals. Frost et al. demonstrate that low concentrations of iron in serum, caused by the hormone hepcidin, inhibit the body’s response to vaccines and...
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RT @Drakesmith_Lab: Two new contributions from us: @MeganRTeh on the wild metabolism of CD8 T-cells in iron deficiency and why they love as….
nature.com
Nature Reviews Immunology - Iron is crucial for cellular metabolism, but its availability varies greatly within and between individuals and populations. This Review highlights how iron regulates...
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RT @BenjaminYWiner: Our paper on PM abundance as a regulator for myeloid function is out at SI I would like to th….
science.org
Plasma membrane abundance controls myeloid cell phagocytosis, migration, and in vivo responses against fungal pathogens.
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RT @ScientistBecs: Thrilled to have this story out online @ImmunityCP!! Together with @SunLab_Official, we highlight how dietary fasting im….
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Great thread from Felix on @sarah_wideman ‘s amazing recent paper. Sarah makes us ask what’s happening to the host immune response when we think about iron availability and malaria! It was a lot of fun working with them both and seeing this story develop.
I am really glad to highlight a fantastically thorough paper from @sarah_wideman and the @Drakesmith_Lab which I was allowed to have a small role in. It highlights the central role of cellular #iron levels in host cells during #malaria. A thread🧵.�.
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RT @MauroCorradoBio: Interferon-γ couples CD8+ T cell avidity and differentiation during infection
nature.com
Nature Communications - Although IFN-γ is known to regulate T cell function and expansion during virus-specific responses, its impact on T cells with varying avidity for antigen remains...
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RT @BenjaminYWiner: Hi everyone, I’m excited to share a pre-print of my postdoc work 🍾 We found a protein (Gb4) tha….
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RT @WCM_IMP: Congratulations to IMP graduate student Deeksha Deep @deeksha_deep in Sasha Rudensky’s lab on the successful defense of her th….
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RT @RheumSmith: Excited to share our work in @NatureImmunol on synovial fibroblasts in rheumatoid arthritis! A wonderful collab between @HS….
nature.com
Nature Immunology - Smith et al. present a resource detailing drivers of transcriptional heterogeneity of synovial fibroblasts cell states in the inflamed joints of human patients with rheumatoid...
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RT @DLMQN: What does melanoma do with all that fat?. Incredibly excited to share that our work on lipid droplets in melanoma is finally out….
nature.com
Nature Communications - Lipid droplets are a dynamic organelle found in a variety of cell types, most prominently in adipocytes. Here, the authors find in zebrafish and human cells that lipid...
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RT @jburnmurdoch: This is corroborated by NHS data, which shows that the huge increase in voluntary resignations over the past two years ha….
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RT @dana_peer: Thrilled to share our new paper, jointly with Sasha Rudensky, spearheaded by Ari Glasner, Sam Rose and Roshan Sharma. Wh….
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RT @YRMeng: Excited to share that my postdoctoral work is finally out @NatureCellBio, thanks to all the great people @Simona66274422 @SThon….
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RT @leomagneschi: Extremely honored to have joined the #charter #dinner @StEdmundHall last night and represent @IngenzaLtd at this fabulou….
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RT @p_openshaw: Andrew Pollard nails it again: The UK's NHS has transformed healthcare by training clinical research leaders, but they must….
theguardian.com
Pressures on the NHS, a lack of doctors and post-Brexit delays are hampering our ability to develop cutting-edge drugs, says Prof Sir Andrew Pollard, director of the Oxford Vaccine Group
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RT @DocAShah: Pleased to have been awarded a Starter Grant for CLs. Thank you @acmedsci. Looking forward to working with @AEArmitage1 on me….
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RT @RafaJArguello: 📢🙏 share and help us to find a motivated PhD candidate for an 🤯🤓🤩 opportunity at @CancerImmunoAMU . 🧪🧠 Exciting #PhD cal….
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RT @MSKEducation: #WednesdayMotivation is to continue celebrating 2023 #WomensHistoryMonth! Today we highlight Adriana Mujal, PhD (@amujal)….
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RT @CleeteRichter: Really glad my PhD work is now released. Here is the promised 🧵. In the @aksimonlab, we have been investigating for a l….
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RT @CleeteRichter: I am very happy to see my first first-author paper published @embojournal, very excited to see the main work of my #PhD….
embopress.org
image image Cell‐extrinsic effects of autophagy on inflammation remain poorly understood. This study identifies adipocyte autophagy as an important contributor to an adipose‐driven anti‐inflammatory...
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RT @themis_brown: We are hiring - postdoc positions available! If you are interested in joining a highly collaborative and supportive team….
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