Jesper D. Gunst
@JesperGunst
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MD PhD working on clinical trials in #HIV using #bNAbs, #LRAs and/or #TLR agonists.
Aarhus, Danmark
Joined April 2017
🚨 We’re hiring! 🚨 Join the Gaebler & Ibrahim Labs for an exciting postdoc position at the intersection of virology & gene regulation! Help us uncover mechanisms behind HIV latency using cutting-edge genome engineering. More info:
nature.com
The mission of the Berlin Institute of Health at Charité (BIH) is medical translation: transferring biomedical research findings into novel approac...
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Exciting news! Our survey report with @ECDC_EU on #HIV #stigma in the #healthcare setting is now available. Huge thanks to everyone who contributed to its success! 👉 https://t.co/b1gJZ6p1xL Don't miss the presentation on Friday by @TeyNoori at #AIDS2024
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How to interpret and how to manage low level viremia? Hearing now from @JesperGunst with important insight from amazing session chair @Rokx1 at #YINGconf24
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The survey on "Measuring #HIV knowledge and attitudes in the #healthcare setting" is still available until 5 Dec! Complete it today or spread the word in your network. 🔄 Available in 38+ languages! 🌍 Survey link: https://t.co/FxThqDHwnV
@ECDC_EU
eacsociety.org
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Editorial: “Host Receptor Targeting to Treat #Covid19” by @JesperGunst and Ole Schmeltz Søgaard https://t.co/SaOv3GWzau
#SARSCov2 #InfectiousDisease @AarhusUni_int @AUHdk @syctong @Josh_S_Davis @jasonroberts_pk
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If you work in a healthcare setting in Europe or Central Asia, you are invited to take this survey on stigma & discrimination by @ECDC_EU and @EACSociety ⏲️ Deadline: 30 November 2023 #StigmaFree
@ECDC_EU & @EACSociety are measuring HIV knowledge and attitudes in healthcare settings across Europe and Central Asia. Please help promote the survey which can be found here in 38 languages: https://t.co/9cwDErwlCA Deadline is 30 November. 🙏 @EATGx @aidsactioneurop @WHO_Europe
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Inhibition of intracellular enzymes like TMPRSS2 that are vital for replication of #SARSCoV2 may be an effective treatment strategy for #COVID19. Gunst and Sogaard comment on recent clinical evidence for the effect of TMPRSS2 inhibitors like nafamostat. https://t.co/SaOv3GWzau
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Exciting news! The Berlin Institute of Health at Charité @berlinnovation is launching its BIH PhD Program, focused on medical translation and innovation. 🌟 Fully funded doctoral positions for translational projects 🌟 Open for applications until Nov 22 https://t.co/5trDu8pVoK
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European AIDS Clinical Society (EACS) vil undersøge viden og holdninger om HIV blandt sundhedsfaglige på tværs af Europa. Så hvis du har ca. 10 min til at udfylde - vil vi blive glade! @Sygeplejeraadet @laegeforeningen @Sundpol @regionerne
https://t.co/ftw7zJS4tj
eacsociety.org
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In people with HIV-1 undergoing antiretroviral treatment interruption, lefitolimod + broadly neutralizing antibodies did not delay viral rebound more than antibodies alone, raising questions of how to optimize combination immunotherapy to control HIV-1
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Review on Immunomodulation with IL-7 and IL-15 in #HIV-1 infection. @viruseradicate
https://t.co/e3JH3rm3m7
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Results from the Titan Study show promise that broadly neutralising antibodies (BNABS) are a component of a future HIV Cure.
hivcure.com.au
Treating HIV involves daily treatment for life. The TITAN study investigated a strategy using bNABs, towards an HIV cure
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Lastly, thanks to all our collaborators. My mentor: @ole_s_sogaard
@AUHdk @HealthAarhusUni @AarhusUni_int @NussenzweigL @AwesomeJonesLab @AlfredHealth @TheDohertyInst @DAREtoCureHIV @Oslounivsykehus @UniOslo @AalborgUH @OUHhospital @AmagerHvidovre @Rigshospitalet @RHGoedstrup
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No added benefit of combining lefitolimod with bNAbs compared to bNAbs alone. The bNAbs are doing something and support further investigation as part of curative strategies. Additionally, we need better assays for bNAb prediction.
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No strong evidence of a bNAb-mediated vaccinal effect on HIV-1-specific CD8 T cell response.
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During the early phase of ATI, bNAbs prevented HIV reservoir expansion, whereas non-bNAb recipients had expansion of their reservoir.
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