Jeffrey Chen
@JeffChenMycoLab
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TB Research Scientist - Principal Investigator @VIDOInterVac @Usask Also on https://t.co/mKBPYWh2MQ - all views, opinions and comments are my own
Canada
Joined March 2020
Excited to see the PhD work led by Sarah Danchuk published today at @PNASNews . Virulence hierarchies within the Mycobacterium tuberculosis complex. Thanks to all the authors and collaborators, and especially kudos to Sarah: https://t.co/mNTbRuvW0F. .
pnas.org
The Mycobacterium tuberculosis complex (MTBC) includes M. tuberculosis (M. tb), the primary cause of human tuberculosis, M. bovis, the classical zo...
Sarah Danchuk summarizes differences between M. bovis infections and M. orygis infections at her brilliant PhD defence. Two slides, two outcomes.
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When food is wasted, so are the resources used to produce it, including #water, energy, and labour. Minimize what you throw away. Explore #FoodWaste prevention tips: https://t.co/nACmUElRuF
@CEMonthCanada @CircularOnline
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We're about to create the 1st gen of scientists who can't research without AI. And honestly? I'm not sure if that's evolution or devolution! 𝗦𝗰𝗶𝗲𝗻𝘁𝗶𝘀𝘁𝘀 𝗮𝗿𝗲 𝗻𝗼𝘄 𝘂𝘀𝗶𝗻𝗴 𝗖𝗵𝗮𝘁𝗚𝗣𝗧 𝘁𝗼: — Extract key findings from dense papers in seconds — Design entire
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In doing so, this talented young scientist discovered 1) a novel activator of ESX-1 gene transcription and 2) a novel vaccine that is as protective as BCG but does not compromise existing TB diagnostic tests.
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Delighted to share our report in Microbiology Spectrum. Slim Zriba (PhD student) engineered Mycobacterium smegmatis to produce a functional Mtb ESX-1 system. https://t.co/6m5jnmI0gz
journals.asm.org
In this study, we modified Mycobacterium smegmatis, which is often used as a surrogate model organism in mycobacterial research, to produce and assemble a functional Mycobacterium tuberculosis (M....
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A potential antimicrobial treatment for Mycobacterium tuberculosis from a repurposed drug: https://t.co/J6B05Ihmdu
nature.com
npj Antimicrobials and Resistance - The Parkinson’s drug benztropine possesses histamine receptor 1-dependent host-directed antimicrobial activity against Mycobacterium tuberculosis
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VIDO is building a new animal housing facility that will expand our research capacity—housing everything from mosquitoes to ticks to bats🦟🕷️🦇. These vectors are crucial for disease spread, and access to them will help us better prepare for emerging threats. #VIDOis50
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New TB research! 🧫 A collab between VIDO & UBC shows the Parkinson’s drug benztropine may help immune cells fight TB. VIDO confirmed it works in infected mice using our CL3 labs. Great example of shared expertise in action. 🔗 https://t.co/sLcAMuzk4c
#TBResearch #usask #ubc
nature.com
npj Antimicrobials and Resistance - The Parkinson’s drug benztropine possesses histamine receptor 1-dependent host-directed antimicrobial activity against Mycobacterium tuberculosis
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In 50 days, VIDO will celebrate its 50th anniversary!! 🎉 Follow along as we count down by sharing a daily fact about VIDO’s evolution and innovations over the past five decades! #VIDOis50
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Our paper is out! The Parkinson’s drug benztropine possesses histamine receptor 1-dependent host-directed antimicrobial activity against Mycobacterium tuberculosis. Thanks @henok_sahile and team for your great work. #repurposing @UBC #TB #HDT
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A must read for young scientists! A career in science requires a thick skin. https://t.co/qT0cj1fRzW
link.springer.com
EMBO Reports - Academic science is a bumpy road with many setbacks and students should be better prepared for losses and failures along the way.
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📣We have decided to extend the application deadline for LMIC and non-LMIC awards to April 7th! Please help us spread the word and share the updated flyers within your networks on social media? Applications can be submitted via the ISV Congress website https://t.co/TuyHmx85QG
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Eliminating tuberculosis in Canada IS within reach if we work together. Read our statement for #WorldTBDay to learn how we are working with Indigenous and government partners to achieve this goal: https://t.co/HSWNFM9hN8
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This #WorldTBDay, we stand in solidarity with the millions who are affected or lose their lives because of tuberculosis every year. The effort to #EndTB is urgent. Global health budgets are being cut around the world and TB rates right here in Canada are rising. Thanks to our
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Our @unizar colleagues, Ainhoa, Cris and Santi, were on TV today for #WorldTBDay2025 discussing publications on new compounds, the Hollow Fibre system, integration of AI in clinical trials and the upcoming public plenaries at our general assembly in May!
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To commemorate World TB day, got to discuss the state of TB in SK and our TB research @VIDOInterVac with Adam Hunter on CBC Radio https://t.co/bbtYjAczw5
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🎙️On #WorldTBDay, VIDO scientist Dr. Jeffrey Chen @JeffChenMycoLab joined @600CJWW to share how his lab is advancing vaccine research to #EndTB. Learn how VIDO is driving innovation to protect global health. #vaccines #InfectiousDisease #OneHealth @USaskresearch
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Amazing thesis work led by Sarah Danchuk now submitted for review and posted as preprint: https://t.co/bnYO6Vro2J. Short summary: M. bovis & M. orygis manifest enhanced virulence compared to M. tuberculosis in natural model (calves) and small animal model (mice).
Sarah Danchuk summarizes differences between M. bovis infections and M. orygis infections at her brilliant PhD defence. Two slides, two outcomes.
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