Jediael Ng
@JedNzy
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🌱 biochemist enthusiast | Rubiscosome and evolution. Postdoc @kahochberg, pHD @omc111. 🇩🇪🇸🇬
Joined November 2020
Free, professional illustrations of research organisms! 🎨🐁🪼🪱 We compiled original vector/raster graphics of 70+ organisms & viruses into a CC0 library. All by @ArcadiaScience’s Audrey Bell Check it out & show us how you use them! https://t.co/2k9erWsyUl
#scicomm #sciart
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We're hiring a DFG-funded PhD student (TVöD E13, 65%) at Max Planck Institute, Marburg to study quorum sensing in Klebsiella & host–pathogen interplay. 3 yrs, start flexible. Apply by Sep 30, 2025 (rolling). Send 1 PDF to laganenka@mpi-marburg.mpg.de
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🚨 We’re recruiting an undergrad! 🔬Study how algae fix 30–40% of global CO₂—and help build future crops 🌱 🧪 Get hands-on research experience in molecular biology and beyond! 📩 Learn more and apply today: https://t.co/C4IZ4a1VWj
#UndergradResearch #CO2Fixation #UWmadison
shanhelab.org
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I am soon seeking passionate and driven PhD candidates to join me on this exciting journey. Together, we'll explore new frontiers in science and contribute to sustainable solutions for our planet. Feel free to reach out if you're interested in being part of this emerging lab!
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NTU Singapore invites applications for the prestigious Lee Wee Nam Professorship in Life Sciences, with a focus on Plant Science. Lead interdisciplinary research and shape the future of plant biology! 🌿🍀🌻🌴#PlantScience #AcademicJobs
https://t.co/VBptnapbkn
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If you are interested in microbiome, metabolomics, aging and precision medicine, this is a great opportunity to do postdoctoral training in Singapore!
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So glad to see our work on cardiovascular structural biology is finally online. A great team work! @BeneschResearch @GehmlichKatja @mirandacollier @KaHochberg @ReidAlderson @DominikSaman @janirbolla @KavliOxford
https://t.co/z3xBDPvUrs
nature.com
Nature Communications - Filamin C is a key actin-binding protein involved in cardiomyopathies and musculoskeletal disorders. Here, Wang et al reveal that it interacts with the heat shock protein...
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This is a wild paper. The anaerobic biochemistry is definitely worth your while (and beyond me to explain), but let me try to explain why this is also an evolutionary bombshell. This is about how nitrogen fixation evolved as we know it.
I'm truly excited to announce our new publication in @Nature unraveling a central picture of the Methyl-coenzyme M reductase (MCR) activation machinery and it's strong ATP dependency - kudos to @AnujR2d2 for the fantastic illustration! LINK: https://t.co/OmMRWWtNR8
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I'm truly excited to announce our new publication in @Nature unraveling a central picture of the Methyl-coenzyme M reductase (MCR) activation machinery and it's strong ATP dependency - kudos to @AnujR2d2 for the fantastic illustration! LINK: https://t.co/OmMRWWtNR8
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🚨 Don’t miss your chance to apply for the 3 open PhD positions in our group! 🌞 Project I : #computationaldesign of #photoenzymes for solar-driven nitrogen reduction to ammonia. 🧪 Apply now! Screening starts April 1 🔗 https://t.co/3TWmECB3GX
@mpi_marburg @maxplanckpress
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I am more than happy to see this story to be out. We show another inhibition manner to Acetyl-CoA synthetase. Great thanks to mentor Gert and Joh. also great thanks to my best old friend Yifei as well as all contributed 🍀🍀🍀
A wonderful piece of work by Liu Zheng - enjoy the reading: Regulation of acetyl-CoA biosynthesis via an intertwined acetyl-CoA synthetase/acetyltransferase complex | Nature Communications @Uni_MR @mpi_marburg
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Site-saturation mutagenesis of 500 human protein domains | Nature
nature.com
Nature - Large-scale experimental analysis of Human Domainome 1, a library containing more than 500,000 missense mutation variants across more than 500 human protein domains, reveals that 60% of...
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Happy to share our story on evolution of protein quaternary structure! We discover an astounding variation in assembly across evolutionary timescales contrasted by strong functional conservation suggesting a significant role of non-adaptive processes https://t.co/81PXFUJqyc 👇🧵
nature.com
Nature Communications - Many enzymes form homo-oligomers, but it is often not clear why. This study follows the evolution self-assembly in citrate synthases across their phylogeny and finds it to...
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New paper from the lab: https://t.co/UxYhC9EFeT. You may remember the strange fractal assemblies we discovered in citrate synthase. Well, the reason we even found that protein is that we were interested in how conserved self-assembly is in an enzyme with a very basic function.
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Exciting news 🚀 @MathiasGirbig and @KaHochberg helped showing that essential proteins for animal #stemcell regulation are much older than previously thought, dating back over 700 million years. Check it out👓 https://t.co/W05d0FVHDq
mpi-marburg.mpg.de
A new study published in Nature Communications reveals that critical proteins involved in animal stem cell regulation are much older than previously thought, predating the origin of animals that...
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Excited to share my first paper as a postdoc with @KaHochberg @mpi_marburg! We've made some fascinating discoveries about the evolution of animal stem cells in colab with @jauchr and @deMendoza_Alex. 🧬🔬 Link: https://t.co/YPMo9Pjfmr (1/n)
nature.com
Nature Communications - The pluripotency program is maintained by transcription factors from the Sox and POU families. Here they identify SOX and POU factors from unicellular relatives of animals...
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Greetings Phylogenetic aficionados! We humbly present “A general substitution matrix for structural phylogenetics.” Estimated using QMaker and AF structures. Hope this continues to inspire more investigations in the field
biorxiv.org
Sequence-based maximum likelihood (ML) phylogenetics is a widely used method for inferring evolutionary relationships, which has illuminated the evolutionary histories of proteins and the organisms...
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Our latest preprint: @Sriramgarg calculate a general substitution matrix for structural phylogenetics and used it to root the tree of life. https://t.co/41a20Bx1SB 1/n
biorxiv.org
Sequence-based maximum likelihood (ML) phylogenetics is a widely used method for inferring evolutionary relationships, which has illuminated the evolutionary histories of proteins and the organisms...
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I have a PhD scholarship available for a student to join my group @ntusg in the January 2025 intake. The student will work on a project related to the cellular biochemistry of the diatom pyrenoid. Here is our first paper on the topic:
pnas.org
The slow kinetics and poor substrate specificity of the key photosynthetic CO2-fixing enzyme Rubisco have prompted the repeated evolution of Rubisc...
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Happy to share my first pre-print out of my post-doc in the @erblabs at the @mpi_marburg. If you are If you are interested in the evolution of intrinsically disordered proteins and how they are connected to carbon fixation through Rubisco, give it a read
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