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Isa Lucet Profile
Isa Lucet

@Isa_Lucet

Followers
259
Following
435
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10
Statuses
347

Lab Head Chemical Biology @WEHI_research | Structural Biologist shedding invisible πŸ«₯ light on (Pseudo)Kinases|Drug Discovery | Promoting STEM Leadership

Australia, Melbourne
Joined September 2021
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@Isa_Lucet
Isa Lucet
2 months
Absolutely thrilled to see ProteinDJ released. Many thanks to @joshuamhardy Dylan Silke and the team Junqi Pan, Andrew Thompson, Julie Iskander, @TonyPapenfuss for their enormous amount of work, making this pipeline open source.
@joshuamhardy
Josh Hardy
2 months
I am thrilled to release ProteinDJ: a high-performance and modular protein design pipeline. Our open-source workflow incorporates #RFdiffusion, #ProteinMPNN, #FAMPNN, #AlphaFold2 and #Boltz-2. It is a fast, free, and fun way to design proteins (1/5) https://t.co/IOlC0JKvOL
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@Isa_Lucet
Isa Lucet
9 months
Proud of the @Isa_Lucet team from @WEHI_research , Emily park @CCeMMP , Lyn Deng , Dylan Silke, Jean-Max Mazeri, @joshuamhardy & andrew thompson, showcasing their latest research, everything Ephrin receptors, DCLK1 & Protein DJ synthetic binders at @LorneProteins.
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@ONJCRI
ONJ Cancer Research Institute
1 year
πŸ’« Our new publication in @scisignal reveals insights into gastric cancer progression! Funded by @latrobe, Dr Shoukat Sterle & team found inhibiting DCLK1 reduces tumour growth and prevents cancer from reshaping its environment. Congrats to the team! πŸ‘‰ https://t.co/L938JsYJz3
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@pseudokinase
James Murphy
2 years
Awesome to see this fantastic study of the elusive EphB6 pseudokinase in print at long last https://t.co/jrI6AqZ1xL Massive congrats to star PhD student @LungYu_Liang (now in Frankfurt) who bravely took on this toughest of projects with @Isa_Lucet and me
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@Isa_Lucet
Isa Lucet
2 years
Many thanks to @KRogers1001 and her team @geogphotog Mike M, Lacklan W and to @DebnathGhosal and Andrew Leis for their dedicated support and to all others. Thanks to @nhmrc , Melbourne Research Scholarship and @WEHI_research for funding.
@pseudokinase
James Murphy
2 years
Awesome to see this fantastic study of the elusive EphB6 pseudokinase in print at long last https://t.co/jrI6AqZ1xL Massive congrats to star PhD student @LungYu_Liang (now in Frankfurt) who bravely took on this toughest of projects with @Isa_Lucet and me
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@Isa_Lucet
Isa Lucet
2 years
Thrilled about our latest Pseudokinase research published today in @CommsBio, showing EphB6 power in promoting cell cell adhesion through formation of intercellular tubes. Many congratulations to our star PhD student @LungYu_Liang.
@pseudokinase
James Murphy
2 years
Awesome to see this fantastic study of the elusive EphB6 pseudokinase in print at long last https://t.co/jrI6AqZ1xL Massive congrats to star PhD student @LungYu_Liang (now in Frankfurt) who bravely took on this toughest of projects with @Isa_Lucet and me
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@bj_charles
Charles Bayly-Jones
2 years
@joshuamhardy hey mate, I enjoyed your talk. TEMPO is a taking off! A really great initiative. If we can, Monash should contribute more material or content, whatever helps. Keep it up 🀘
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@CCeMMP
ARC CCeMMP
2 years
@CCeMMP group photo of centre members/affiliates at #cryoz23 - a great turn out in Brisbane! And thanks to outreach committee members for coordinating our 'macromolecular' assembly photoshoot πŸ˜€ @arc_gov_au #croEM #croET (credits to @LouBrillault for the photo).
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@joshuamhardy
Josh Hardy
2 years
ARC CCeMMP members enjoying a lunch break during the CRYOZ23 cryo-EM workshops. We've been learning cryo-electron tomography, modelling, and image analysis. @CCeMMP @UQ_SCMB
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@TheFlorey
The Florey
2 years
Calling scientists and chemists in Melbourne πŸ§‘β€πŸ”¬ Coming all the way from Copenhagen, Prof Meldal will *next week* present his Nobel Prize-winning work in 'click chemistry' work to the scientific community in Parkville πŸ§ͺ Register your attendance here: https://t.co/vRyWAFztQa
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@WEHI_research
WEHI (Walter and Eliza Hall Institute)
2 years
A fantastic achievement for a home-grown Australian discovery. Congrats to WEHI #structuralbiologists, @Isa_Lucet @dr_opatel for their contribution to structure-based #drugdiscovery of #momelotinib during their time at @MonashUni in partnership with Cytopia. #WomenInScience
@GSK
GSK
2 years
#News for #investors and #media: The @US_FDA has approved our new treatment for #myelofibrosis that may address key manifestations of the disease, namely anaemia, constitutional symptoms and splenomegaly.
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@demishassabis
Demis Hassabis
2 years
Excited to share #AlphaMissense our new AI system that can classify whether genetic mutations (missense variants) are benign or harmful - a critical step toward uncovering causes of many diseases, from cystic fibrosis to cancer. In @ScienceMagazine today
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@Isa_Lucet
Isa Lucet
2 years
A shining example of innovation, showcasing the power of integrating structural biology in early drug discovery and academia/industry partnership. Kudos to the incredible teams at Monash & Cytopia. Special shoutout to the many women involved #WomenInScience
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@ampliatx
Amplia Therapeutics
2 years
In exciting news for Australian biotech this week, momelotinib, a drug co-invented in Melbourne by Amplia CEO, Dr Chris Burns, has been granted approval by the FDA for the treatment of myelofibrosis. Read more: https://t.co/fK7AF74pKT $ATX #biotech #innovation #FDA #drugdiscovery
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fiercepharma.com
For the JAK inhibitor momelotinib, which GSK obtained in its $1.9 billion acquisition of Sierra Oncology, a three-month delay at the FDA was worth the wait. | For the JAK inhibitor momelotinib, which...
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@emblebi
EMBL-EBI
2 years
AlphaFold has given us millions of protein structure predictions, but analysing these can be tricky due to computational limitations. Foldseek Cluster is a new algorithm that can perform structural comparisons of every #AlphaFoldDB protein prediction. https://t.co/jdJmLfCCSA
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@GrasLab
GRAS Lab
2 years
After months of preparation it is D day for our conference on #LongCOVID in Melbourne. Today we are coming as a community with patients, healthcare workers, researchers and policy makers to work together to advance our understanding of the disease, to provide better care.
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@Isa_Lucet
Isa Lucet
2 years
Many congratulations @BlewittMarnie @srpasricha too for your appointments as Deputies.
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@Isa_Lucet
Isa Lucet
2 years
Many congratulations Alan. Very fortunate to be at WEHI.
@WEHI_Director
WEHI Director
2 years
It’s a tremendous honour to step into the acting director shoes @WEHI_research. Working alongside my acting deputies @BlewittMarnie and @srpasricha, our staff, students, collaborators and supporters, I’m looking forward to the exciting journey ahead. - Alan Cowman
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@WEHI_Director
WEHI Director
2 years
It’s a tremendous honour to step into the acting director shoes @WEHI_research. Working alongside my acting deputies @BlewittMarnie and @srpasricha, our staff, students, collaborators and supporters, I’m looking forward to the exciting journey ahead. - Alan Cowman
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