Ikegami lab
@IkegamiLab
Followers
94
Following
42
Media
11
Statuses
58
A team of ambitious scientists. Studying cell nucleus, gene regulation, cardiovascular disease, and progeria disease. Recruiting students and postdocs to join!
Cincinnati Children's Hospital
Joined August 2020
Today we did a journal club on this very interesting paper. Still puzzling how Lamin A and Lamin B become so different!.
cell.com
Polyploid nuclei in heart muscle cells are thought to be a barrier for heart regeneration, but how they are generated is unknown. Han et al. demonstrate that low Lamin B2 levels trigger formation of...
0
3
15
Our PhD student Nonso Nduka received Best Question Award at the DSRM (Development, Stem Cells & Regenerative Medicine) program retreat. Congratulations, Nonso! @MDBCincy
1
1
11
RT @biorxiv_cellbio: One step 4x and 12x 3D-ExM: robust super-resolution microscopy in cell biology #biorxiv_cellb….
0
1
0
Congrats to our SURF undergrads Ellie Rohrer & Jake Childress for their first ever conference presentations at AHA #BCVS2024 !
0
0
10
Lab lunch at Dewey's Pizza celebrating Summer Undergraduate Research Fellows (SURF) Jake and Ellie!
0
1
9
We did a journal club on this preprint from Abby Dernburg lab today. This suggests: weak nuclear envelope => nuclear PIEZO activation => apoptosis. Really interesting work. Bonus: textbook examples of "killer experiments"!
biorxiv.org
Successful sexual reproduction relies on robust quality control during meiosis. Assembly of the synaptonemal complex between homologous chromosomes (synapsis) regulates meiotic recombination and is...
0
1
6
Curious about what “nuclear envelope rupture” looks like, how that impacts heart functions, and why it may be important in heart disease?. Check out our new paper in Cell Reports!
cell.com
En et al. report pervasive nuclear envelope ruptures in cardiac myocytes in a mouse model of nuclear lamin-related cardiomyopathy. Surprisingly, nuclear envelope ruptures do not activate cGAS-STING...
4
16
52
Undergrads from @ThomasMoreKY visited @IkegamiLab, @catmak lab, and @YutzeyLab today to explore research at @CincyChildrens! Thanks for visiting us!
0
0
2
Is cGAS-STING important for cardiomyopathy with nuclear envelope ruptures? Check out our new preprint!.
0
1
3
MaryKay from @ThomasMoreKY concluded her amazing summer undergraduate research in our lab! Congratulations, and thanks for your great work!
0
2
6
Our new paper in collaboration with @MoskowitzLab is now published! Great job, Jeff and Chul!.
ETV2 primes hematoendothelial gene enhancers prior to hematoendothelial fate commitment
2
2
9
RT @CellReports: ETV2 primes hematoendothelial gene enhancers prior to hematoendothelial fate commitment
cell.com
Mechanisms driving the specification, commitment, and differentiation phases of fate determination remain elusive. Steimle et al. investigate the activity of the hematoendothelial master transcript...
0
3
0
RT @BlackInGenetics: If you're a Black-identifying graduate or undergraduate studying genetics, make sure you check out our BIG fellowship!….
blackingenetics.com
0
36
0
RT @CellCellPress: Our Juneteenth-themed issue is out! It features several articles highlighting the voices, perspectives and stories of ov….
0
169
0
Our division of Molecular Cardiovascular Biology at Cincinnati Children's has a new Bioinformatics Analyst position open. We are super collaborative division. Come work together with us.
jobs.cincinnatichildrens.org
Careers at Cincinnati Children's Hospital Medical Center
0
1
0
RT @ChrisToseland: I don’t usually post personal news but Clinicians have told us to pull every lever. Our daughter has with #dipg Brain c….
0
16K
0
Students @ThomasMoreKY visited us to learn about research activities and opportunities @IkegamiLab and @CincyChildrens. It was fun interacting with the future generation of scientists!
0
0
3
