The synthesis of anilides with a chiral C(═O)–N axis has relied on direct installation of the chiral C(sp2)–N(sp2) bond or enantioselective modification of the peripheral groups. However, these...

We report a palladium-catalyzed sequential oxycyclization of indole-tethered allene to construct oxepino indole cores with yields up to 91%. This method showcases the C2 umpolung activation of...

Nature Synthesis - The isolation of a crystalline radical cation carbon(I) species, generated via single-electron transfer between a carbodicarbene and a nitroaromatic compound, is reported. The...

This review covers the history of fluorenyl cations from Deno's first report in 1954 on the parent fluorenyl cation to the present. The parent cation and most derivatives have only been observed as...

A 19F NMR spectroscopic probe, p-fluorobenzonitrile, is used to evaluate the relative Lewis acidity of boranes. The resulting scale is compared with the Gutmann–Beckett method which uses triethylph...

Migratory insertion is a key elementary step within organometallic chemistry, frequently encountered with most transition metals. However, in the realm of gold catalysis, the migratory insertion step...

Herein, we disclose an unprecedented gold-catalyzed 1,2-carboxyarylation of alkenes through ligand-enabled Au(I)/Au(III) catalysis. Unlike other approaches for the arylative functionalization of C–C...

This perspective covers the chemistry of cyclopentadienyl cations from the first synthetic attempts generating transient variants to their successful isolation earlier this year. They are highly...

Reductive coupling of perimidine based N-heterocyclic germylene and 4-iodophenyl isocyanide afforded a highly colored and luminescent bis-spirogerma species with unprecedented simultaneous C−N and...

Similar to pyridine, which is a structural analog of benzene, 2-azaborole can be viewed as a structural analog of borole, in which the CH group at the 2-position is replaced by an N atom. Due to its...