Grey Monroe
@Grey_Monroe
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would love to meet over a coffee and talk about genomes and evolution Asst. Prof. @ UC Davis.
Davis, USA
Joined February 2014
Are mutations random? Here is a brief survey of groundbreaking mechanistic work that all evolutionary biologists should be familiar with:
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The abstract deadline for "Mutations in Time and Space 2025" is in a week! Please register here: https://t.co/4zc1tygOMv
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Spread the word! Registration for the "Mutations in Time and Space" conference is open. The meeting is all about the origins, patterns, and consequences of mutations across cells, individuals, populations, species. Abstract submission deadline: Jan 17th https://t.co/KMEHdXnLMQ...
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Very happy and excited to announce that I'll be starting my own research group at @emblebi! The group will focus on lineage tracing, somatic evolution and the origins of cancer. Interested in doing a postdoc in the group or know someone who is? Please reach out!
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Cost of having DNA methylation: DNA replication by DNA polymerase epsilon is a source of C to T mutations in CpGs, especially methylated ones. This expands our understanding of one of the most widespread endogenous mutational mechanisms.
nature.com
Nature Genetics - A new method called polymerase error rate sequencing (PER-seq) can measure the nucleotide misincorporation rate of DNA polymerases. DNA polymerase ε mutants produce an excess...
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Interested in the evolution of expression noise and how it affects gene retention following duplication? Come to my talk at 10:15 on Sat (516B)!! This is part of the thematic symposium organized by Daniel Weinreich @DanWeinreich and Gonzalez Bravo Ignacio #Evol2024
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🧵🌳 Our new manuscript is out! We explored how somatic mutations in trees spread and propagate through different layers of the plant, improving our understanding of the genetic underpinnings of plant growth and diversity. #PlantScience #Genomics
https://t.co/TbU1JFXSaz
genomebiology.biomedcentral.com
Background Plant meristems are structured organs consisting of distinct layers of stem cells, which differentiate into new plant tissue. Mutations in meristematic layers can propagate into large...
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Happy to share our new preprint, reviewing the expansion of the MutS gene family in plants. Feedback welcome! https://t.co/iJxQHyw15G
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A couple of great lab talk/poster combos at #icar2024 this year. Starts with @LensinkMariele (co-advised with @Grey_Monroe) talking about mutation rate heterogeneity and evolution Tuesday in session C12. For bonus info, stop by poster and ask about trans plasticity work.
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The real point is control: transposons as controlling elements in evolution, development and disease 20-22th Nov @ University of Leicester https://t.co/Zs39Rw0dG4 Early bird registration deadline approaching! @GenSocUK Fantastic speaker line-up and opportunities for talks
genetics.org.uk
This three-day conference will run from Wednesday 20th to Friday 22nd November 2024 in Leicester. Background: When Barbara McClintock first described transposable elements in the 1940s, the scienti...
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Very excited to share that our new work is finally out🎉 We demonstrate that the chromatin remodeling factor DDM1 “opens” the nucleosome structure. https://t.co/hCEC1ftTi6 You can also access to the PDF file as bellow: https://t.co/qmR1xJxPxe
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Maybe the best news of the year! New Director at the @mpi_ie/@maxplanckpress 🥳 Nicola Iovino @Iovino_Lab is the new Director of the Department of Developmental Epigenetics – studying the impact of epigenetics on biological diversity & evolution. More: https://t.co/xsOSLoSfmB
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So proud to have been chosen to serve @OfficialSMBE as president-elect. The society has inspired me in so many ways. I am glad to be granted the chance to promote its values. Thanks members! #SMBE2024
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🔔Happy to announce that our recent story is now online in @NAR_Open. In this study we chemically mobilized the Copia LTR #retrotransposon ONSEN (ATCOPIA78) in Arabidopsis and analyzed the consequences on genomic imprinting and heterochromatin formation.🧵 https://t.co/ZODh35Z7dB
academic.oup.com
Abstract. Genomic imprinting, an epigenetic phenomenon leading to parent-of-origin-specific gene expression, has independently evolved in the endosperm of
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So proud of my lab for our latest work out today in @Naturepub. We took advantage of transposable elements and CRISPR to perform targeted insertion of cargo DNA in the Arabidopsis and soy genomes. Led by @mcliupeng. https://t.co/wSvr1uuEbF. 🧵
nature.com
Nature - Fusion of rice Pong transposase to the Cas9 or Cas12a programmable nucleases provides sequence-specific targeted insertion of enhancer elements, an open reading frame and gene expression...
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Scientific journal @Nature has published research authored by scientists in our @Slotkin_Lab. The publication focuses on a technology called TATSI, which enables faster and less expensive production of improved plants. Learn more: https://t.co/al5QKjErCy
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The @Slotkin_lab @DanforthCenter is hiring a new laboratory technician. Lots of cool work to be done on transposable elements! Please retweet to spread the word!
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Lucky to be part of such a great team. New lab photos from resident photographer and PhD student Kehan Zhao💚
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H3K4me1 recruits DNA repair proteins in plants https://t.co/k5i7gHpsZT interesting findings! @Grey_Monroe @ThePlantCell
academic.oup.com
DNA repair proteins preferentially repair regions with the epigenomic feature H3K4me1, resulting in mutation rate heterogeneity in plants.
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Still time to apply for this PhD position to study somatic evolution in plants with @Euphrasiologist and myself. Lots to explore in this field!
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