GeertCarmelietLab
@GeertLab
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Skeletal cell metabolism and hypoxia signaling in bone development, regeneration and bone disorders @KU_Leuven
Leuven, Belgium
Joined January 2019
Big congratulations @SLoopmans for your excellent PhD research!! This is one of the best moments as a mentor to see the success of team members. Many thanks to all co-authors and everyone in our research team as well as funding by @FWOvlaandere and @KU_Leuven!!
Very happy to share the final chapter of my PhD Research with @GeertLab, now online in @NatMetabolism, revealing that the pentose phosphate pathway in #chondrocytes is crucial for ER redox homeostasis and cell survival to ensure chondrocyte functioning and bone lengthening (1/4)
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RT @SLoopmans: Very happy to share the final chapter of my PhD Research with @GeertLab, now online in @NatMetabolism, revealing that the pe….
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Many thanks @NatMetabolism for publishing and highlighting our research, all members of our lab, the excellent collaboration with @bernthie and especially first author @SteveStegen.
Top Citations 2024: #20🏆✨. @GeertLab (@KU_Leuven) and co-authors describe the role of the serine synthesis pathway in osteoclast differentiation through #epigenetic regulation of NFATc1 expression 🦴🧫.
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Congratulations @vishalmkrishnan and @ralfhadams for this beautiful work, linking the regional differences in #vasculature with the #metabolic heterogeneity of the bone microenvironment.
Bone remodeling is traditionally driven by osteoblasts and osteoclasts, but our study reveals a third essential player: "Type R capillaries". Excited to share my PhD work from @ralfhadams lab, now published in @NatureCellBio. 🧵1/8👇 🐭🔬🦴
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RT @FrezzaLab: "Cellular ATP demand creates metabolically distinct subpopulations of mitochondria".
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Congratulations Rik and @SilviaMonteag : interesting interaction between important signaling pathways!.
New @NatureComms Publication Alert! We uncover a Wnt/IGF1 link driving joint damage in #osteoarthritis. IGF1, induced by Wnt signaling, worsens the joint disease, but IGF1 targeting could open doors to new therapie. @SilviaMonteag @AnaEscribano7 1/14.
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It was a pleasure being in your thesis committee and discussing the numerous interesting findings.
It has been an incredible journey! .Thanks to @FendtLab and my PhD thesis committee @GeertLab @CoolsJn @CorbetCyril @MariaRodrColman for their support and the amazing discussion! .@FWOVlaanderen @komop_tgkanker @KU_Leuven @vib_ccb.
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RT @JoyYWu: In @CellStemCell: a tribute to Charles “Chuck” K.F. Chan (1975–2024). Thank you Tom Ambrosi and Mike Longaker for remembering a….
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Excellent presentation by @SteveStegen on serine #metabolism in #bone: cell types and outcome matters!!
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Many thanks Lydia!! @Lydfinley.
Excellent, inspiring and concept-broadening Keynote presentation of Lydia Finley !!! Great start of the day.
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Excellent, inspiring and concept-broadening Keynote presentation of Lydia Finley !!! Great start of the day.
Learning about metabolic control of healthy and pathological skeletal cells and their microenvironment at #ASBMR2024 Pre-meeting
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Off to #asbmr2024! Looking forward sharing our findings on how the #serine synthesis pathway regulates #bone cell function at the energy #metabolism pre-meeting on Thursday! @ASBMR @GeertLab
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looking forward to all these presentations!! And the metabolism pre-meeting will be interesting.
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Congratulations Courtney!! Interesting findings. See you in Toronto #ASBMR2024.
Happy to be able to share our latest findings about glutamine metabolism in osteoclasts! . Glutaminolysis provides nucleotides and amino acids to regulate osteoclast differentiation in mice | EMBO reports
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