Frank Zaucke
@FZaucke
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ECM biochemist interested in cartilage, Co-Chair Cartilage GRC 2023 Head of the Dr. Rolf M. Schwiete Research Unit for Osteoarthritis
Frankfurt/Main, Germany
Joined March 2020
Great to hear ๐ we are on the right track!
๐ Most Cited #Cartilage extracellular matrix-derived #matrikines in #osteoarthritis Anna E. Rapp and Frank Zaucke https://t.co/uIuwXAPzCj
#AJPCell #Review
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Submit your original research on this important topic to @OACJournal by May 2026
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New content online: Synovial fluid as a complex molecular pool contributing to knee osteoarthritis https://t.co/6eaA9PRy65
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Excited to share our latest work on a novel mutation in a gene that causes non-classical OI๐ TENT5A-Associated Osteogenesis Imperfecta: Long-Term Follow-Up and Molecular Insights
academic.oup.com
Abstract. OI is a genetically diverse disorder characterized by bone fragility and deformities, with most cases attributed to dominant mutations in collage
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More than exited to have contributed to this review๐
New content online: Restoring articular cartilage: insights from structure, composition and development https://t.co/0eRtXz3Bn6
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Happy to have contributed to the second paper on the effect of immobilization on cartilage: Immobilization by 21-days of bed rest causes changes in biomarkers of ...
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The following link provides open access (for 50 days) to a recent study our lab contributed to! Thanks to the lead authors to involve us in the analysis of Matrix-mediated activation of murine fibroblast-like synoviocytes
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It was a great pleasure to edit this book๐ with Antonio Rossi. It describes how the #ECM is altered in inherited skeletal disorders like #osteogenesis imperfecta, #achondroplasia, #Marfan, #EDS etc. thanks to @aforlino @KasiaPirog1 @mamareen8 @WannAngus and many others
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๐จplease have a look at our latest review article๐จ Osteogenesis imperfecta: shifting paradigms in pathophysiology and care in children - Read on https://t.co/J6LDf7ilCz
@degruyter_brill
degruyterbrill.com
The formation of functional bone requires a delicate interplay between osteogenesis and osteolysis. Disturbances in this subtle balance result in an increased risk for fractures. Besides its mechan...
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๐ECI Publication๐ @ZsJeneiLanzl & @Fzaucke 1) Joint tissue interactions: meniscus, bone, fat tissue, synovium & synovial fluid 2) Degeneration of cartilage ECM & bioactive fragments 3) Receptors, ion channels, signaling pathways & cellular metabolism https://t.co/1R9Rw6PZCk
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Here comes the link to the full text of our Osteoarthritis year in review 2024: Biology - in @OACJournal Thanks to @ZsJeneiLanzl and @DFG_FOR2722 @Matrixbiologie @IntSocMatBio
https://t.co/PheOQIhAGh
oarsijournal.com
Osteoarthritis (OA) research is a fast-growing and extremely wide field, in which a substantial increase in knowledge has been achieved over the last year. It covers many different topics, however, a...
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I am more than excited that our manuscript (written by @ZsJeneiLanzl and myself) has been accepted for publication๐๐๐๐๐๐ Osteoarthritis year in review 2024: biology - Osteoarthritis and Cartilage
oarsijournal.com
Osteoarthritis (OA) research is a fast-growing and extremely wide field, in which a substantial increase in knowledge has been achieved over the last year. It covers many different topics, however, a...
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๐ป #New #BasicScience in #OAC๐ป Obeidat et al. suggest a standardized approach for histologic assessment and reporting of synovial pathology in mouse models of OA. @Draliasandoqa @SUNGYEON_KIM
@CARLA_SCANZELLO @AM_MALF @LITTLECB5001
@REM7101
@KEVIN_GBURT ๐ https://t.co/D1AuY3k3dw
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Fantastic study describing a gene therapy approach that could prevent obesity-induecd osteoarthritis๐ Congrats, Farsh and team ๐
Congrats Ruhang Tang & @NHarasymowicz for our new @PNASNews paper on gene therapy for fat-1, an enzyme that converts ๐-6 fats (frying oil/meat) to ๐-3โs (fish/nuts). Increased ๐-3:๐-6 reduced inflammation, osteoarthritis, and markers of cell aging! https://t.co/gmaUdOQFYu
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This was a fantastic annual meeting and I learned a lot...not only from our invited guests๐!
@DFG_FOR2722 Annual meeting and Summer school were a success! Huge thanks to all participants for presenting their projects and to our invited guests for their insightful, thought-provoking talks. Excited for potential collaborations and future opportunities @UKKoeln @UniCologne
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๐จDont miss this opportunity and be part of our collection! ๐จ There is still time to submit your manuscript ๐ฅ๐ฅ We are looking forward to your contribution @ArthritisRes ๐๐ป๐๐ป๐๐ป๐๐ป๐๐ป๐๐ป๐๐ป
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Our Giulio did a fantastic job presenting his work on human osteochondral cylinders as preclinical osteoarthritis model #MBE2024 in Lyon ๐ @Matrixbiologie @ZsJeneiLanzl @CHANGE_ECM
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