Thomas Frank
@FrankFishLab
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Neurobiologist. Group leader @uniGoettingen, formerly @MPIforBI
Goettingen
Joined October 2019
Paper alert! We combine modeling and experiments to study “balanced” EI assemblies of co-tuned excitatory and inhibitory neurons in a memory network. TL; DR: EI assemblies suppress “runaway activity” & “runaway correlations” - which interfere w/ memory capacity & discriminability
Computational functions of precisely balanced neuronal assemblies in an olfactory memory network https://t.co/Pou6lAigDb
#biorxiv_neursci
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We are proud to present our new preprint “Correlative light and electron microscopy reveals the fine circuit structure underlying evidence accumulation in larval zebrafish”, just posted on bioRxiv ( https://t.co/pYHYh26vSo). (1/10)
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Are you using GCaMP8 or planning to switch from GCaMP6? Then check out this new preprint from our lab! https://t.co/TZcjFdeYG4 - Calcium imaging - GCaMP8 vs. GCaMP6 - Spike inference - Imaging + ephys ground truth With F. Helmchen, K. Svoboda @svoboda314, M. Rozsa & X. Fang.
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Together with cSAXS, the Coherent X-ray Scattering Group at PSI, we are looking for a Postdoctoral Fellow on High-Throughput X-ray Ptychographic Imaging of 🧠: https://t.co/3hSegYoWgg + work at 4th gen synchrotron + interdisciplinary team science + Swiss salary and benefits
psi.ch
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The mouse cochlea is another excellent and beautiful sample imaged with our new rapid isotropic light sheet microscope. Big thanks to Lennart Roos for preparing the sample precisely. The video shows the spiral ganglion neurons (SGNs). @AuditoryNeuros
https://t.co/2Pgdas128H
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I'm excited to share our latest work at Huisken Lab, where we have developed a high-speed, aberration-corrected light sheet microscope that delivers sub-micron isotropic resolution for imaging a wide range of cleared tissues, such as a mouse brain. https://t.co/2Pgdas128H
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Should I stay or should I go?! New study by @BaierLab shows that in cichlid fish mother and larvae follow their own intrinsic schedules during brood care. This leads to the larvae leaving their home shell exactly 9 days after fertilization. Find out more:
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Nature Hippocampal neuronal activity is aligned with action plans https://t.co/6gc2eVfO7X
nature.com
Nature - Using high-density electrophysiological recordings, how internally generated cell assemblies are updated by action plans to meet external goals is explored.
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Human hippocampal CA3 uses specific functional coHuman hippocampal CA3 uses specific functional connectivity rules for efficient associative memory: https://t.co/jIPLNVw884 Ssparse connectivity in human hippocampal CA3, and reliable transmission in CA3-CA3 synapses.
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Great opportunity to apply to a young lab and work on exciting questions about how memories are transformed into actions, with an amazing mentor! Don't miss it!
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Pls retweet! Just five more days to apply for this cool (admittedly, I'm biased) and fully-funded #PhD project in our lab! #jobalert
Have you ever wondered how memories are processed downstream of the #hippocampus and how this is affected by #Alzheimer's? We believe we may find some answers by riding all the way down the fornix to the mammillary body. Apply here for a #PhD with us: https://t.co/ilR7zId8Nu
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Happy to share my second paper with Peter Dayan on our decision-theoretic approach to perceptual multistability (see the tweeprint of the first paper here https://t.co/Qq3ABjSYoP): A decision-theoretic model of multistability
biorxiv.org
Perceptual multistability has been studied for centuries using a diverse collection of approaches. Insights derived from this phenomenon range from core principles of information processing, such as...
Happy to share my first post-doc paper with Peter Dayan just published at @NeuroCellPress "Multistability, Perceptual Value, and Internal Foraging" Paper (free access before Oct 18th): https://t.co/h0Z3RGtO0H No access? Email me at neuron2022@shervinsafavi.org 🧵👇
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Congratulations to Fabian Sinz (@sinzlab)! The computer scientist and neuroscientist at our university has been awarded an #ERC Consolidator Grant. His project “Vision2Action” will use #AI to show how movement influences visual processing in the brain: https://t.co/MrQE5LFlf7
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We have a new PhD position available. Please spread the word and retweet. The project will combine retina recordings, computational modeling, and optogenetics to help further develop vision restoration therapy. See here for more information: https://t.co/FnP2JTsHay
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Wir freuen uns mit @yourUMG und @moser_tmoser über die Bewilligung eines neuen SFB. Ziel ist es, vorhandene Therapien für Patient*innen mit Sinnes- und Bewegungseinschränkungen zu verbessern und neue Behandlungsansätze zu finden. Mehr unter https://t.co/ihtCRr318z
@dfg_public
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How natural stimuli lead to highly correlated ganglion cell activity in primate (marmoset) and mouse retina. Now out in @nature. https://t.co/PIYdb7Xi1Q
nature.com
Nature - Species-specific gaze shifts with natural stimuli drive correlated spiking in retinal ganglion cells.
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Announcing the 2nd Subcortical Sensory Circuits meeting! We have amazing speakers, including Sonja Hofer (@SonjaBHofer) and David Anderson (Caltech) Subcortical Sensory Circuits: From Perception to Behavior Feb 11-14, 2025 Assisi, Italy https://t.co/EFEQZMj3zU
#EMBOcircuits
meetings.embo.org
Subcortical sensory circuits play a fundamental role in the perception of the outside world. However, they are often thought of as relay stations that passively transmit sensory information to the co…
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Strikingly different neurotransmitter release strategies in dopaminergic subclasses https://t.co/pQ8e8zdFdz
#biorxiv_neursci
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📣 The first bit of my postdoc work is out! 📣 We described another layer of heterogeneity in the fascinating dopaminergic neurons in the olfactory bulb. Follow the thread to read a tale about axonless neurons, dendrites releasing GABA and self-inhibition 👀 🧵 @GrubbLab
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If you need an inline perfusion heater, for example for your patch clamp rig, here is one for <30$. https://t.co/g69QK2xpeM
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