Feltham Lab
@FelthamLab
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We smash & trash; we #PROTAC and attac 💣 We discover new drug targets & hijack the #ubiquitin system to remove them💊 Tweets by PI @BekkyFeltham @WEHI_research
Melbourne, Victoria
Joined November 2019
@FelthamLab managed to get a pic all together today. Love this one ☺️ @WEHI_research #EnjoyingScienceTogether
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RT @kdonovan1008: Heads up for those working in ubiquitin biology and targeted protein degradation—Lorne Ubiquitin 2025 is happening 20–23….
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RT @BekkyFeltham: Had an exciting morning of #TargetedProteinDegradation at the launch of Ternarx! @ternarx49306 Fantastic to have strong s….
wehi.edu.au
Australia has cemented its role in becoming a major player in the next-generation of medicines with the launch of Ternarx
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🔬2024 Lab Update! 🌟. Farewell to incredible team members, @DanielSimpsonAU and Anna Gabrielyan. Wishing them success as postdocs!💙Excited for new faces and opportunities in 2024. Here's to innovation, collaboration and new discoveries🚀 #LabLife #NewBeginnings #Science2024
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Unlocking the secrets of the E3 ligase MIB2!🕵🏻♂️ . Our new paper @PNASNexus unravels the mysteries of MIB2 in mice with the cpd mutation, and its unexpected role in wound healing 🐁🩹 An excellent study we're thrilled to share!#wehiresearch #MIB2Discovery .
academic.oup.com
Abstract. Skin inflammation is a complex process implicated in various dermatological disorders. The chronic proliferative dermatitis (cpd) phenotype drive
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RT @LechtenbergLab: Abstract submissions for 2024 @LorneProteins, incl. the Satellite Meeting on "Ubiquitin signalling: Molecular mechanism….
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Great talk from @mediocre_jake today talking all things E3 ligase, a favourite topic in the @FelthamLab @WEHI_research
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Well done Anna Gabrielyan for a fantastic talk for @AusCellDeathSoc @WEHI_research today. Great story and really interesting data 🤓😎
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RT @Stephintje: The Vervoort and @FelthamLab @BekkyFeltham are looking for an enthusiastic Research Assistant who wants to join our labs fo….
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RT @WEHI_research: WEHI researcher Dr @BekkyFeltham was always intrigued by biochemistry. These days Dr Feltham heads up a #UbiquitinSignal….
wehi.edu.au
At university, Dr Rebecca (Bekky) Feltham knew there was something special about biochemistry.
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@FelthamLab Christmas Shenanigans continued @CargoRestaurant with our end of year awards. The best mistake award this year going to @BekkyFeltham #MerryChristmas
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@FelthamLab Christmas Shenanigans @archiebrothers, great afternoon of arcade game fun 😁 #festiveseason #MerryChristmas
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Well done @TamerAly_Tam for an excellent PhD confirmation seminar today @WEHI_research #PhDconfirmed #phdlife
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RT @Pengyu19: #cIAP1-based %degraders induce #degradation via branched #ubiquitin architectures | Nature Chemical Biology .
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RT @iDikic2: An expanded Lexicon for the Ubiquitin code by @idikic @IBC2_GU & Brenda Schulman @MPI_Biochem 😳.New types of #Ubiquitin modifi….
nature.com
Nature Reviews Molecular Cell Biology - Recent studies have expanded our understanding of the mechanisms and functions of ubiquitylation. Pathogens rewrite ubiquitylation to promote infection...
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RT @RapeLab: Wow!!! Congratulations @Nurix_Tx for having achieved a complete (!) response in a patient with aggressive Non-Hodgkin's Lympho….
ir.nurixtx.com
Complete response observed and ongoing in a patient with multiply relapsed/refractory diffuse large B cell lymphoma (DLBCL) Dual BTK degradation and immunomodulatory activity achieved by day 8 and...
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RT @pottslab: A big mystery solved? Endogenous function of the CRBN Ligase revealed by Christina Woo et al @Nature!! Spoiler…it’s all about….
nature.com
Nature - C-terminal cyclic imides are physiological degrons that enable the ubiquitin E3 ligase adapter protein cereblon to target substrates for degradation.
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