Duchen Lab
@DuchenLab
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Understanding the interrelationships between calcium signaling, mitochondria and free radicals in cell physiology and pathophysiology / @uclbiosciences / @UCL.
London, United Kingdom
Joined July 2020
Today marked my last day at @DuchenLab and @uclbiosciences @ucl. Over the past 4 years, I've had the pleasure of meeting some fantastic individuals and gaining valuable knowledge. Grateful for the experiences that have molded me as a scientist. Eager for what the future holds!
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It’s World Mitochondrial Disease Week, and we’re bringing together relevant content across our journals to highlight the importance of this field. Read more from @michael_duchen in our news item, and discover our journal content below. https://t.co/ynS6VQOSaX
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@Michael_Duchen’s lab, with @RobPitceathly (@UCLIoN) and Claudio Raimondi (@QMULWHRI), has a grant from The British Heart Foundation focused on inter-relations between atypical #strokes, #mitochondrial #DNA mutations & vascular endothelial function. @thebhf @ucl #cardio
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🎓🥳 Huge congratulations to Dr. Rob Tidswell on earning his well-deserved PhD degree! 🎉👏 Wishing you continued success as you embark on this exciting new chapter in your career! 🚀
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Duchen and Szabadkai labs basking in the summer vibes while taking a well-deserved day off in beautiful London! ☀️🌸
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Wrapping up an engaging couple of days with a presentation by our final year PhD student @GabboV introducing his latest data on #mtDNA point mutations in human iPSC derived myofibers #iPSC #mitochondria Now on to the wine to celebrate🍷
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Great talk by @ChiHaoyu on his #PhD project modelling Down syndrome associated Alzheimer’s Disease using patient derived NPCs #mitochondria #iPSCs @uclcdb
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Our PhD student @ChackoAnitta opening today’s Postgraduate Research Symposium @uclcdb presenting her work on “Investigating the impact of mtDNA point mutations using patient fibroblasts and hiPSC derived neuronal models”
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UCL has got quite the fantastic representation in this funny group photo at #EuroMit2023 😄 #TeamUCL
@DuchenLab @uclbiosciences @LondonMito @ucl
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Thank you to everyone who attended our @uclcdb social yesterday and made it a great one! Here are some pictures of the event @DuchenLab & @SzabadkaiLab
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Congratulations @ChackoAnitta for this well-deserved recognition!
Thank you to all the board members of the @BFWGraduates for organising such a great RPD event. I thoroughly enjoyed the day listening to all the great presentations and the discussions that followed. I'm also delighted to have been awarded the 1st prize for my presentation 😀
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We are delighted to present The Keilin Memorial Lecture to Professor Michael Duchen in 2024! @michael_duchen’s work currently focuses on the dialogue between cell signalling pathways in mitochondria, and the roles of mitochondrial dysfunction in disease.
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The mitochondrial ATP synthase as an ATP consumer—a surprising therapeutic target
link.springer.com
The EMBO Journal - The mitochondrial F1Fo‐ATP synthase uses a rotary mechanism to synthesise ATP. This mechanism can, however, also operate in reverse, pumping protons at the expense of ATP,...
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IoN UCL PubMed: PolyQ length-dependent metabolic alterations and DNA damage drive human astrocyte dysfunction in Huntington's disease
pubmed.ncbi.nlm.nih.gov
Huntington's Disease (HD) is a neurodegenerative disease caused by a polyglutamine (polyQ) expansion in the Huntingtin gene. Astrocyte dysfunction is known to contribute to HD pathology, however our...
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Thanks for the invite @MitOtalks, really looking forward to it! @LondonMito @MRCMitoCluster @UCL_QS_CNMD @UCLIoN @ICGNMD
Our next MITOtalk is approaching, and Robert Pitceathly will tell us about mitochondrial diseases and how to diagnose them. Thursday, 17h00 CET.
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Our #BogueFellowship recipient, @GabboV, had an unforgettable experience taking part in an exchange at @Harvard. Read more about his experiences here. https://t.co/KHFcKV2qVn
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Really excited to have been awarded the Bogue fellowship allowing me to spend 3months in @DrWilliamHwang ’s lab at Harvard. The Bogue fellowship generously funds PhD students/post docs to travel to the US for research or courses. @SzabadkaiLab @UmberCheema @michael_duchen
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Fantastic to be joined by #mito researchers from across @ucl to celebrate word mitochondrial disease week. #WMDW #lightupformito @UCLBrainScience @DuchenLab @UCLchildhealth @4Lilyfoundation
https://t.co/wz1HN9unbo
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It’s over 34 years since the first cause of mitochondrial myopathy was identified @LondonMito by Holt, Morgan-Hughes, and the late Prof Anita Harding. Since then 100s of causes have been identified but we still lack a cure. #mitoawarenessweek #WMDW @4Lilyfoundation @MitoAware
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