Chuck Simonton
@DrChuckSimonton
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Interventional Cardiologist and Innovator. CMO, Abiomed, Inc. Tweets represent my own opinion.
Silicon Valley
Joined November 2014
OCT-guided PCI offers unparalleled lesion characterisation and optimisation beyond conventional angiography, yet remains underused. This comprehensive review analyses technical aspects, procedural strategies, and contemporary evidence shaping its clinical role. #EIJBestOf Read
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To my Abiomed family and customers- today I launched my campaign for Governor of Massachusetts. I ask for your prayers and support as I focus on another struggling “company” called Massachusetts. I promise to put the people of Massachusetts first just like we put Patients First
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This was truly the birth of what we all do today as therapeutics in the cath lab. It was an honor to meet Adolph Bachman at the Gruentzig Society meetings, especially the 30th (2007) and 40th (2017) anniversaries in Zurich. What a leap he took for mankind. @BillONeillMD
September 16, 1977, Andreas Gruentzig performed the 1st coronary angioplasty in Zurich. Below is the story, told by the 1st patient himself, Adolph Bachman, and his doctor, Bernhard Meier. This was the birth, not just of interventional cardiology, but a whole new branch of
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Babar, glad you got to be at the Sanger Clinic dating back to early PTCA in 1980’s, early BMS 1990’s, 1st DES in N.C. in 2003, and now top AMICS program and top 10 in PROTECT IV with leader Nyal Borges. Makes Hadley Wilson + I very proud. @GreggWStone @HadleyWilsonMD
Wonderful to visit @AtriumHealth Sanger Heart & see first that their amazing shock program serving the metro Charlotte community. Lots of talented friends doing amazing thing! @nyalborgesmd @HadleyWilsonMD @EstherSHKimMD Monique Oye, David Cox, @DrChuckSimonton @HenryFordHealth
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Indeed. DanGer Shock RCT keeps on giving us confidence that what we do immediately in pts with AMICS can make a difference for the rest of their lives, but it must include early mAFP (Impella). @JNJMedTech @NavinKapur4 @GreggWStone @BillONeillMD @SandeepNathanMD @agtruesdell
Congratulations to Jacob and the Danger Shock team, at #ESC2025 they shared long terms outcomes from the trial, demonstrating persistent benefits of Impella in AMI-CS out to 10 years of follow up.
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Indeed. This makes total sense to all of us who’ve been in this for many years. The better you can identify Ca++ the bigger lumen with less dissection you can achieve with stenting using roto or IVL. OCT is the most optimal way to see and quantify Ca++.
One of the best uses for OCT is guiding stent implantation in calcified lesions. Our analysis from ILUMIEN IV is now published in EHJ, showing 40-50% reductions in TVF and MACE with OCT guidance in moderate or severely calcified lesions. Free access link:
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Check out Eric Topol’s book Deep Medicine. AI has the potential to ultimately make medicine more humane, automating the things you hate to do and giving you more time with patients.
Was interviewed by @TIME magazine about chatGPT in healthcare and it got me wondering whether we’ve forgotten what doctoring really is - a human exercise married to science and trchnology. Anyway not sure when it’ll come out but interesting times indeed @CMichaelGibson @DLBHATTMD
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Wow Alex. What a case! Congrats on an amazing salvage. Hopefully back to reasonable QOL.
Valvular (AS) ⚡️🫀💥 Shock and Arrest. Bedside ECLS. BAV 🎈and Impella unload. IVUS 👁️ guided LM-LAD PCI-Rota 💎 (delivered via wedged-in MC)-DES. ECMO decannulation. Impella removal under TEE (to assess AI) and RHC. Extubation. Home for Rehab…then ultimate TAVR… #ShockTeam
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Tnxs @cardiacinterv for allowing me to share reflections on “A Decade of Quality Improvement: The National Cardiogenic Shock Initiative” NCSI’s recommendations have become the SOC for AMI-CS management post-Danger @iyadisseh @wohnsmd @agtruesdell Link:
citoday.com
Babar Basir, DO, FACC, FSCAI, shares insights into the development and growth of the NCSI, discussing its impact on cardiogenic shock care over the past 10 years, as well as future endeavors.
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62yo man, NSTEMI, EF:21%, Mean PA: 35mmHg, PCWP:20mmHg, CPO: 0.56. @ProtectedPCI w/ Impella CP for LM/LAD last remaining vessel. Impella was absolutely essential as the patient lost arterial pulsatility during vessel manipulation. Amazing performance of the device
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What an achievement by the PROTECT IV investigators! 4 years of enrollment preceded by 1 1/2 years of planning. The largest PCI strategy RCT in our field’s hx, and oh how important for ischemic HFrEF patients. Now to complete 1-3 years f/u in all pts. @GreggWStone @NavinKapur4
Today we celebrate an important and exciting milestone as the PROTECT IV study completes enrollment with 1252 subjects randomized! This achievement would not have been possible without the support of each PROTECT IV site. We value and appreciate your collective contributions to
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Really excited to see the great program put together by @Allison_Dupont @SandeepNathanMD @behnam_tehrani leaders in the CS space. If you want to continue to adv your CS team or need some help getting started please sign up for the pre-con …
📺In an interview during 2024 #SCAISHOCK, @Babar_Basir summarizes the key takeaways for the conference and invites you to join us in Tampa for 2025 #SCAISHOCK.🌴⚡ Learn more and register➡️ https://t.co/VugyeXi8B5
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Congrats. The big learning in this data is that the actual observed risk in Impella-supported HRPCI in over 1000 pts was half of what was predicted by either BCIS or NCDR PCI risk scores, suggesting outcome enhancement by Impella support. Fascinating. @GreggWStone @mmamas1973
Novel risk score for Impella-HRPCI to calculate in-hospital mortality. Easy to remember and can be useful to discuss risk of mortality with patients undergoing #HRPCI. 📌 https://t.co/8zLGuDIQ2Q
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https://t.co/AelyiH2bXM Many of us 😭 our eyes out at news of this @RajaHatem @DrDarshanDoshi @DrAllenJ @wjn_md @SanjogKalra @AmirMasoumiMD @djc795 #ajaykirtane. So many of us owed so much to him professionally and personally. I would never be where I am without him. He was the
tctmd.com
Karmpaliotis leaves behind a legacy of teaching his profound skills in complex PCI and his passion for patients and family.
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This week we lost a close colleague and soldier in our field, Dr Dimitrios Karmpaliotis. And I mean tireless soldier: for patients, fellows, colleagues and family. His skill and persistence to help patients inspired many who will carry this onward. Privilege to call him a friend.
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On Memorial Day weekend, as you visit with family and friends, remember why you have what you have in the U.S.A. and never forget…history teaches us…. Just visit Arlington; or Normandy where they never made it home…God Bless these men and women… @MikeMinogueABMD @agtruesdell
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Can’t believe it’s been 6 years!! Stakeholders in the field are clearly aligned by this “common language” for staging cardiogenic shock. Now onward in your role at SCAI to setting standards to operationalize DanGer Shock and save lives! @GreggWStone @NavinKapur4 @Babar_Basir
My SoMe reminded me that 6 yrs ago today I had the honor of presenting the @SCAI SHOCK classification to the world. Here’s to the massive progress since then by so many people! #DLC next! @Babar_Basir @agtruesdell @behnam_tehrani @NavinKapur4 @BurkhoffMd @davebaran @djc795
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The mechanistic plausibility of why these will work in HFrEF is highly compelling, and clearly displayed by the RELIEVE-HF data. Exciting times for HF patients. @NavinKapur4
Our publ in EHJ: state of the art review of intrer-atrial shunting - potentially a major breakthrough in HFrEF and selected pts with HFpEF. Add to this the ongoing placebo-procedure controlled ALLAY-HFrEF trial which has just started randomizing 350 HFrEF pts.
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Special day today at Carolinas Medical Center as Hadley Wilson was honored after “retiring” from the cath lab. He was my “wingman” (and I was his) as we built PCI in the Carolinas. Here we are with Nyal Borges, now the PCI “master” at Sanger Clinic. @HadleyWilsonMD @NavinKapur4
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