Dimple Notani
@DimpleNotani
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Associate Professor@NCBS. Interested in signaling driven 3D chromatin dynamics and distal regulatory elements
NCBS, Bangalore, India
Joined November 2019
If you want to build such modern reagents and like doing a bit of organic chemistry and some biology, do consider joining my lab ( https://t.co/xHh6bl9nFX) at National Centre for Biological Sciences (NCBS) Paper link:
lnkd.in
This link will take you to a page that’s not on LinkedIn
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The deadline for common entrance exam (JGEEBILS) for I-PhD and PhD is on 26th October. Please apply! @NCBS_Bangalore @TIFRScience
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🏆Big wins for NCBS at the 9th Asia Chromatin Meet at IISER-Pune!🤩 Four of our graduate students, Nija George, Surya Sarathi Das (@r_sabarinathan’s lab), Shreyas Ratnaparkhi, and Subhashis Indra (@DimpleNotani’s lab) - won Best Poster Awards!🌟 🎉Congratulations to all!
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#PhDone !🎓 Congratulations Dr. Sudha! 🎉 Sudha Swaminathan from Dr. @DimpleNotani 's lab successfully defended her thesis! 👇Scroll to learn about her work on how nuclear myosin-1 plays a role in controlling the molecular processes inside cells when exposed to estrogen. (1/4)
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Please register for Asia Chromatin Meeting 2025, at IISER Pune, 9th-11th Oct. 2025 https://t.co/puxTueOzLI
sites.google.com
About Research on Chromosome-Chromatin biology has experienced significant growth in recent years. The discovery of various chromatin modifying enzymes, remodeling machineries, and high-resolution...
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Students and Post-docs, please register for this chromatin meeting. Registration deadline approaching fast! @ranjithpa @NCBS_Bangalore @DeepakNModi @mahipal_ganji @r_sabarinathan @grewal @grewalsh @IISERPune @mbhavana10 @kazu_maeshima @iam_Mridula
Please register for Asia Chromatin Meeting 2025, at IISER Pune, 9th-11th Oct. 2025 https://t.co/puxTueOzLI
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Happy to share our work on how chromatin organization is established for the first time in early mouse embryos, in part via interplay with remarkable hypertranscription. Marvelous work by Guang Yu, Kai Xu, Weikun Xia and Ke Zhang! https://t.co/ZYwqamCi9v
nature.com
Nature - A study reveals progressive cohesin loading and a hypertranscription state responsible for the formation of genic cohesin islands at active regulatory genes in mouse embryos, highlighting...
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Predicting statistics of gene translocation events: role of chromatin compaction and double-strand DNA break https://t.co/5vFnzikcy9
#biorxiv_biophys
biorxiv.org
How the 3D organization of chromatin affects gene translocation is an open question. By Monte Carlo simulation of translocation events in folded chromatin, we examine how the probability of translo...
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We are excited to have @DimpleNotani delivering an interesting Seminar! She will discuss about how RNA, through its ability to interact with transcription factors, plays a critical role in facilitating fast and dynamic transcriptional responses. #seminar #rna
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Published now @genomeresearch how Xist upstream elements regulate gene expression. Excellent work by @SudeshnaMajum18 Thanks @iiscbangalore @ANRFIndia @DBTIndia @EMBO_YIP for support. https://t.co/CFkuOi57wx
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We then used SGE to engineer CHO cells to grow without isoleucine, a feat we could not achieve via rational design and delivery of entire synthetic pathways. Again, mitochondrial localization was favored, with individual clones reflecting ~40-50kb of integrated DNA!
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@biorxiv_genomic Excited to share our paper on the changes in 3D chromatin architecture across cell cycle stages in the pathogenic basidiomycete yeast, Cryptococcus neoformans. @ranjithpa @KaustuvSanyal @DimpleNotani @DuttaShuvadip @rakeshnetha_v
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@xielablife Join us ! Final deadline for registration is May 18, 2025 https://t.co/IGyKnFH7Mt
@4DNucleome @spp2202_dfg
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#PhDone! 🎓 🎉 Congratulations Dr Zubairul! @zubi_ from Dr @DimpleNotani's lab successfully defended his thesis! Swipe to learn more about his work on Chromatin domain boundaries and their role in genome organisation and transcription regulation🧬 👉 (1/6)
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#PhDone! 🎓 Congratulations Dr Rajat! 🎉 @rajat007_mann from Dr @DimpleNotani's lab successfully defended his thesis! 🧵⬇️Scroll through the thread to learn about his work on transcription regulation🧬 (1/5)
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#NewComicAlert! Our latest comic with @TinkleMagazine featuring the inspiring story of Dr @DimpleNotani is out now! Check it out and let us know your thoughts in the comments below! #sciencecomics
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We’re excited to collaborate with @NCBS_Bangalore to launch the PRISM Fellowship (Promoting Research and Inclusion in STEM). It offers an unparalleled opportunity for students from disadvantaged backgrounds to gain research experience, academic skills & mentorship at NCBS.
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Excited to share our new study in @CellReports showing that CTCF-mediated loop switches alternative splicing and promotes EMT. @KakaniParik, @ERPLab_IISERB, @DimpleNotani. Thanks to @DBTIndia @iiserbhopal
cell.com
Kakani et al. reported that hypoxia drives CTCF redistribution across the genome and is associated with the EMT. CTCF-mediated promoter-exon upstream looping regulates the CTCF-mediated RNA polymer...
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Chromatin folks: don't miss GRC/GRS Genome Architecture in Cell Fate and Disease, June 15-20 2025 Ventura, CA. Registration deadline: Mar 18, 2025. https://t.co/Wc1h5YTKDq
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