Catherine Denicourt
@Denicourt_Lab
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Studying how modified ribosomes shape the cancer proteome at UT Health McGovern Medical School in Houston; views are my own
Houston, TX
Joined March 2018
TRMT1L-catalyzed m22G27 on tyrosine tRNA is required for efficient mRNA translation and cell survival under oxidative stress
cell.com
Hwang et al. identify TRMT1L as the elusive methyltransferase responsible for catalyzing the m22G modification at position 27 on tyrosine tRNA. TRMT1L is also crucial for maintaining acp3U and D...
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Thrilled to share our new story on tRNA modifications! @SseuPei @MDA_UTHGrad TRMT1L-catalyzed m22G27 on tyrosine tRNA is required for efficient mRNA translation and cell survival under oxidative stress: Cell Reports
cell.com
Hwang et al. identify TRMT1L as the elusive methyltransferase responsible for catalyzing the m22G modification at position 27 on tyrosine tRNA. TRMT1L is also crucial for maintaining acp3U and D...
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Sseu-Pei Hwang, Dr. Catherine Denicourt Lab: R.W. Butcher Student Achievement Scholarship
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@Xisca_Aguilo and me have curated a collection on translational regulation and #cancer, out now in @NAR_Cancer_EIC 🔗 https://t.co/8waUYVWhRY Contributions from @LorenzoMontana4 @s_millevoi @GebauerLab @johnprensner @Denicourt_Lab @Sblancolab @FallerLab and others #RNA #RBP
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Human TRMT1 and TRMT1L paralogs ensure the proper modification state, stability, and function of tRNAs https://t.co/sThN9fuLb2
#biorxiv_molbio
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TRMT1L-catalyzed m22G27 on tyrosine tRNA is required for efficient mRNA translation and cell survival under oxidative stress. https://t.co/9OZaVRYzCa
#biorxiv_molbio
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Excited to share our work on tRNA modifications placing TRMT1L as the tRNA Tyr m22G27 methyltransferase. Congrats to @MDA_UTHGrad grad student @SseuPei in the @UTGSBSGnE program! Great collaboration with @UCVPResearch
biorxiv.org
Mapping of the epitranscriptome has revealed the chemical diversity of RNA modifications and their functional importance in regulating gene expression. Transfer RNAs (tRNAs) are one of the most...
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Our review on the impact of ribosome biogenesis in cancer is out in @NAR_Cancer_EIC Congrats to @SseuPei a @MDA_UTHGrad in the @UTGSBSGnE program!
academic.oup.com
Abstract. The dysregulation of ribosome biogenesis is a hallmark of cancer, facilitating the adaptation to altered translational demands essential for vari
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Congrats Sseu-Pei!
Sseu-Pei Hwang recently earned a spot in the UTHealth Houston BIG-TCR Training Program in Cancer Research as a 2023 predoctoral fellow. "I believe the BIG-TCR will be the key to completing my training." Please join us in congratulating her on this BIG accomplishment! #WeAreGSBS
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Our study on the p53-regulated transcriptional program induced after inhibition of ribosome biogenesis is online at Molecular Biology of the Cell! Great team effort!
molbiolcell.org
Accumulating evidence indicates that increased ribosome biogenesis is a hallmark of cancer. It is well established that inhibition of any steps of ribosome biogenesis induces nucleolar stress...
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Congratulations to our BCB faculty, Ghislain Breton, PhD @bretonlab for being nominated and voted by the students of our program for the 2021 Distingushed Faculty Award for excellence in mentoring.
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😂Pure gold. The scary part: not beyond the realms of possibility
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Voter suppression ALERT: @GovAbbott limits election drop boxes to one per county. That means one for the 4.8 million people who live in Harris County. During a pandemic.
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We learned to bake bread in this pandemic, we can learn to make our own adobo con pimienta. Bye.
The CEO of @GoyaFoods is at a White House event saying we're "blessed to have a leader" like Trump. Make your shopping decisions accordingly.
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Our SVP shared today a cautionary COVID-19 tale with our @bcmhouston community. You should read it too. Thank you @jmcdeavitt for your leadership. https://t.co/9jnm6UAs6P
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The TMA is sponsoring this event. What in the world? 🤦♀️
Going against the doctor's orders, the Texas GOP Convention will gather in Houston - a COVID hotspot, without a mask requirement, with potentially 6000 ppl indoors. The Texas Medical Association is sponsoring it. via @mvenk82
https://t.co/bCvFSKR9EL
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Wow, I find this particularly discouraging coming from my Institution
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