Dibyendu Dutta
@CuriousModeller
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🌈Evolution, Bacteria, Phage, Models, Experiments, Technology #PrototypeDev #PostDoc @LSI_Exeter @UniofExeter 🇬🇧 #PhD @iitbombay 🇮🇳 MSc SysBio @HydUniv
Exeter, UK
Joined October 2013
BREAKING: Apple just proved AI "reasoning" models like Claude, DeepSeek-R1, and o3-mini don't actually reason at all. They just memorize patterns really well. Here's what Apple discovered: (hint: we're not as close to AGI as the hype suggests)
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What happens to bacterial genomes when they're cloned into yeast? Do they transcribe, do they get silenced, do they get packaged away from the rest of the DNA? This cool study congrats to the Koszul lab team at Pasteur for this great work
science.org
In eukaryotes, DNA-associated protein complexes coevolve with genomic sequences to orchestrate chromatin folding. We investigate the relationship between DNA sequence and the spontaneous loading and...
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"Oh, I'm a *pure* mathematician, I don't write code/do calculations/etc.." "Oh, I'm a *theoretical* physicist, I don't do experiments/analyze data/etc.." Etc. These kinds of statements are typically uttered with an air of intellectual smugness. But what are they really? (1/6)
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We've just launched the 2025 Systems Biology Postdoctoral Call for candidates to join our Institute
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I cannot agree with this more, as I figure out the journey of what I like vs fit into!
But b/c there are *so few* jobs and so many applicants, you're gonna see all the people who were lucky enough to be studying the right thing at the right time get jobs while you don't. You learn that "fit" drives most hiring, and "fit" is all vibes masquerading as "merit"
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How bigs are the cells? Microorganisms in perspective 🦠 [🎞️ MetaBallStudios] https://t.co/WCWWYKjLVg
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Last night at #pint24 was my first time talking science outside a conference! Thankfully it turned out great with an amazingly engaged audience with lot of great questions!😃 Thanks a lot to the organizers for making it happen @orlandorosss @DanJ910 @HarryGreenTKD
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🔬 Journey into the world of Phage Therapy with Dibyendu Dutta at the Bootlegger on Monday, May 13th! Explore the captivating potential of bacteriophages in battling antibiotic-resistant bacteria. Join us for an enlightening discussion! @CuriousModeller #PhageTherapy #Pint24
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What Biology Can Learn from Physics 🚀 World War II shifted physics from a field of brilliant individuals to one of well-managed teams. CERN, LIGO, and the JWST all cost >$1 billion. Biology has had a few "moonshots," but not nearly as many. Why not? Read:
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Was an exciting opportunity to present a glimpse of my work at the @LSI_Exeter to H.E. @VDoraiswami, the Indian High Commissioner to the UK @HCI_London during his visit to the @UniofExeter. With @tiwarianuj_ and @BhingeLab
We were very excited to welcome the Indian High Commissioner H.E. Mr Vikram Doraiswami at the Living Systems Institute @Uniofexeter on Friday. Dr Akshay Bhinge, Dr Dibyendu Dutta, & PhD student Anuj Tiwary showed H.E. Mr Doraiswami around the LSI and explained their research.
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Introducing "data-to-paper": autonomous AI research! We've let it play with the large CDC Health Survey Dataset. Went to lunch. When back, it had already chosen several research topics, wrote data analysis codes, interpreted results and wrote 5 transparent, reproducible papers.
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*DISCUSS* Which problems are treated using the "particle physics approach" (as discussed in the video) in your respective fields? https://t.co/VQV9JrXX8P
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I really like the concept, since today science in most fields is way too complex and collaborations are often not sustainable. Such focused orgs with proper plans may help small labs execute large projects that are usually the exclusive domain of big shot labs.
Rishi Sunak just announced up to £50m in funding for new “focused research organisations.” FROs are a new way of doing science. In effect, they apply the startup model to scientific research. 🧵
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You think ChatGPT is impressive? Wait till you see Microsoft's new Bing. It'll blow you mind away. Here's a comparison of ChatGPT and Bing for: • Outlining a research paper • Brainstorming research questions
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This is hella cool!
Today in ingenious historical experiments: Theodor Engelmann demonstrated that chloroplasts are the site of oxygen production in plants by taking bacteria that would migrate towards oxygen and seeing that they went to the choloroplast (from Howard Berg's "E coli in Motion")
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I have an @EPSRC funded PhD position to work with myself and @michaelsulu, using model microbial communities to improve our understanding of how communities can be used for future bio-industry Get in touch if you're interested and please share/RT https://t.co/kcWIsgSKou
ucl-epsrc-dtp.github.io
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That project was going so well until we ran the gel. N.B.: helmet?? https://t.co/aFUFhMbJZE
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In synthetic biology classes, I ask students what biological function they want to create, and one popular answer is "photosynthesis in mammals". Now, it's achieved! The authors transplanted membrane-coated thylakoids into chondrocytes and mice! Congrats! https://t.co/otmUDiEfSG
nature.com
Nature - Proof of concept of the viability of a plant-derived photosynthetic system based on nanothylakoid units encapsulated in a chondrocyte membrane to enhance cell anabolism in chondrocytes is...
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😱😱🤯
This is an ocean dwelling ribbon worm from the genus Gorgonorhynchus What you can see being discharged is a sticky proboscis, this densely branching structure is a feeding appendage used in hunting. https://t.co/EkoC5hM9VR
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