Emma Colliver
@ColliverEmma
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@TheCrick Visiting PostDoc | Cancer Research, Tumour Microenvironment |@Cambridge_Uni Physics Graduate | All views are my own
London
Joined March 2015
I did it! London Marathon 2025 done. ☑️🏃♀️🥇🙌🏻💜☀️ Thank you to everyone for your encouragement and donations to my chosen charity @PancreaticCanUK. Any last contributions to my fundraising page are greatly appreciated. 🔗 https://t.co/jkJaIBoJdm Congratulations to all runners!
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Just over 2 weeks to go until my @LondonMarathon run in aid of @PancreaticCanUK - Last long run was 21.8 miles 🏃♀️- Pancreatic cancer is a cause close to my ❤️ after the death of a friend - Any donations to my fundraising page are gratefully received 🙏🏻 - https://t.co/jkJaIBoJdm
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Huge congratulations @ZaccaSimo!! So utterly well deserved. Great news to round off a wonderfully successful year. Thank you for the inspiration and mentorship you are providing to so many of us who are setting out on our cancer research careers. 🌟
🎉 So hugely honoured and happy to be selected for the @EMBO Young Investigator Programme 2024 @EMBO_YIP! Such an exciting opportunity for our group @CCG_UCL and so grateful for the support of @uclcancer @uclnews @ucl @CRUKCOLcentre @TheCrick & our funders @CRUKresearch @CR_UK
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We are so grateful to @qianthefirst for this outstanding @NatureGenet News&Views piece highlighting our recent SPRINTER work and framing it so beautifully within the literature. A truly valuable resource! 🙏 Read it here👉 https://t.co/XqvXCkWQlI 🧵Dive into SPRINTER's work 👇
nature.com
Nature Genetics - A novel method for analyzing single-cell genomics enables direct inference of cell cycle and proliferation status, highlighting the diversity of proliferation rates in clonal...
🚨So proud to present the first study from our @CCG_UCL group together with @CharlesSwanton @NnennayaKanu and led by @ojlucas with key collaboration @Ward__Sophie and fundamental support @Rija_Zaidi_ @abi_bunkum & many others Out in @NatureGenet 👇 https://t.co/cd7YkBBDxo 🧵👇
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The human proteomic revolution proceeds with high-throughput assessment, AI analytics, correlation with health and disease, drug interactions, biomarkers https://t.co/VsYD6vGxXp
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Hot off the press!! 🔥 Check out our work on the origins and impact of ecDNA. This was a team effort involving multiple collaborators as one of a three part series on ecDNA in @Nature
ecDNA are rogue genetic material that amplify genes, contribute to treatment resistance and drive genomic heterogeneity. We report on the Origins and impact of extrachromosomal DNA today in @Nature
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Vamos, @RafaelNadal! As you get ready to graduate from tennis, I’ve got a few things to share before I maybe get emotional. Let’s start with the obvious: you beat me—a lot. More than I managed to beat you. You challenged me in ways no one else could. On clay, it felt like I
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1/ This is the next chapter of a story about courageous patients and their families, of multidisciplinary teamwork, and hard-fought steps forward to effective therapy for #DIPG #DMG, a universally lethal cancer of the brain and spinal cord. 🧵 https://t.co/hMe0XYplKz
nature.com
Nature - We evaluated the use of chimeric antigen receptor-modified T cells targeting GD2 (GD2-CART) for H3K27M+ diffuse midline glioma (DMG), finding that intravenous administration of...
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In our new paper just out in Science Advances we investigate mechanisms that may be limiting responses of KRAS mutant lung cancer to KRAS inhibitors and immunotherapy. https://t.co/3ErFb9VBpm
science.org
Spatial analysis identified Tregs as a source of local T cell repression, mediating resistance to KRAS-G12C-i and anti–PD-1.
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https://t.co/n1B55vWxks T cells receive regulatory signals from close neighbours, through ligand-receptor interactions and cytokines. Therefore we dived into the local neighbourhoods of CD8 T cells to investigate why a lung cancer model was resistant to KRAS-G12C-i + a-PD1.
science.org
Spatial analysis identified Tregs as a source of local T cell repression, mediating resistance to KRAS-G12C-i and anti–PD-1.
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"Lung cancer is one of the hardest types of cancer to treat, so working out how to harness the immune system to better target tumours is so important." Read about the new work from Megan Cole, @JulianDownward, @F_vanMaldegem and more ⤵️
crick.ac.uk
Researchers at the Francis Crick Institute, working with the Amsterdam University Medical Centre, have found that immune cells are held back from fighting lung tumours by another type of cell in the...
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@ScienceLab_MCBI @CancerCenterAms @AIIresearch @Ernestorcp @lotte_dewinde @F_vanMaldegem @amsterdamumc Ready for #singlecellclub
@ScienceLab_MCBI? 😀Excited to hear from @EgleKvedaraite (@karolinskainst) on human mononuclear phagocytes in tissue using #scRNAseq, #flowcytometry✨ & #imaging, and @ColliverEmma (@TheCrick) on the PHLEX computational toolkit for #singlecellimaging 🔬
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Together with @CharlesSwanton, delighted to share that our new tool, MHC Hammer - which can detect different types of HLA disruption - mutation, loss, RNA repression and alt. splicing - is now out in #NatureGenetics and available to use… https://t.co/pNGyLKsmmG... 🧵below
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Cancer research PhD opportunities with a talented and supportive group leader. 👇🏻 I had the pleasure of working with Alex during my PhD. Please share with your networks. 🧬
🚨 Interested in spending 4 years studying how tumours evolve and developing new diagnostic methods? Take a look at the Alliance for Cancer Early Detection (ACED) PhD studentships available in my lab @EarlyCancerCam @CRUKCamCentre: https://t.co/hjWRiIEqst Deadline 4th Nov!
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***Wet lab cancer research postdoc opportunity in the Swanton lab*** - https://t.co/0UDgyoESZn It has been a privilege to start my research career with this group and at the Crick.🧑🔬
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This 600-year-old painting is one of the most mysterious in history. That mirror at the back is just 3 inches wide — yet it reflects the entire room in immense detail. Look closer at it and you'll realize nothing is as it seems… (thread) 🧵
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Paris is truly a beautiful city!💜 These are 10 of the most beautiful competition venues at the Paris 2024 Olympics... 1. Grand Palais (Champs-Élysées) - to host Taekwondo & Fencing
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TP53: - Discovered 45 years ago, most cited gene all time - No therapies - 500 million people currently living will die of TP53 mutant cancers without new therapies Our Preprint: - A general strategy for TP53 missense mutant cancers (majority) with prototype small molecules
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The 2004 Summer Olympics opening ceremony https://t.co/FInRrFBw72
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