Kristopher Sarosiek
@CellDeathLab
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The Sarosiek Lab @HarvardChanSPH studies the regulation of #apoptosis in human development and diseases.
Boston, MA
Joined June 2017
The 2025 Young Investigator Summit brought childhood cancer researchers together to discuss the future of their work in a changing landscape. These Alex's Lemonade Stand Foundation-funded scientists receive YI Grants early in their careers, a critical time to establish research
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Don’t miss our next BCDI meeting! 🧠 GPX4 in neurodegeneration—Adam Wahida (Helmholtz-Munich; visiting @MGHCancerCenter, @HarvardChanSPH) 🧬 Targeting phosphate homeostasis in cancer—Daniel Bondenson (@UMassChan) 📅 Mon Nov 3 | 3PM | @harvardmed Quad 🔗 https://t.co/sl332L9g5I
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➡️Join our next BCDI meeting for exciting discussions on immune-competent organoid brain tumor models from Xin Tang @BostonChildrens and immune suppression in ovarian tumorigenesis from @TanjinaKader @harvardmed! Monday Sept 8th at 3PM @ Harvard Med Quad. https://t.co/uOJiL148QG
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We want YOU 🫵 to join The Million Mile Challenge to help kids with cancer! Every September for Childhood Cancer Awareness Month, thousands of supporters walk, run, and cycle to help reach our collective goal of moving a million miles and raising millions for childhood cancer
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📢Informative #radbio review in @IJROBP ⚠️ MYC is an enigmatic oncogene impacting #radiotherapy responses in complex ways. This work focuses on novel approaches for MYC inhibitors. @sueyom @CellDeathLab
https://t.co/xe5AwLjBHg
redjournal.org
The MYC family of transcription factors—comprising c-MYC, N-MYC, and L-MYC—plays a pivotal role in oncogenesis, driving cancer progression and resistance to therapy. While MYC proteins have long been...
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Glad to share our latest @sigtrans_sttt review on #cancer #stemness and #epigenetic. Kudos to @ClaudiaGalassi9 for taking the lead, not possible w/o critical input from Ilio Vitale #offttwitter and @ManelEsteller @CarrerasIJC @FoxChaseCancer Free at https://t.co/F461qTWV44
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Herculean effort from @deadoc80 and team to COMPREHENSIVELY review how #caspases promote or suppress inflammatory signaling. Recent discoveries show that caspase signaling, and ultimately organismal responses, are nuanced and context-dependent. #apoptosis #inflammation
Here comes our latest @NatRevMCB review on the control of #inflammation by #apoptosis, #pyroptosis and #caspases! Kudos to @RuthSAnyc and @Mbv26 for the heavy lifting! Not possible w/o input from @CellDeathLab and Doug Green!! @FoxChaseCancer @HarvardChanSPH @StJude
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Glad to share our latest research published in @NatureComms on identifying HLF as a critical regulator for lung metastasis in solid cancers.
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In a new study, researchers from @MGHCancerCenter and colleagues investigated the treatment of KRAS-mutant non-small cell lung cancer. The study was published in @NatureComms. Read more: https://t.co/dwNyI0H6RO
@chendi_li @CellDeathLab
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📢Another great #radbio review in the @IJROBP #RedJournal Informative review on the enigmatic MYC transcription factor & potential role of MYC inhibitors for #radiotherapy‼️ @sueyom @DeborahCitrin @CellDeathLab PDF 👉 https://t.co/uh55MgohB7
https://t.co/AoBqexgL7T
redjournal.org
The MYC family of transcription factors—comprising c-MYC, N-MYC, and L-MYC—plays a pivotal role in oncogenesis, driving cancer progression and resistance to therapy. While MYC proteins have long been...
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An afternoon with giants of #ferroptosis 😁 and a @bstockwell Lab mini reunion all in one. Almost 20 years of friendship and collaboration. Thought-provoking talk by Scott Dixon. Huge shout-out to @j_ubellacker @CellDeathLab for the vibrant cell death community here in Boston.
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Great talks next week, please join us ! @BIDMC_CancerCtr
➡️Join our next BCDI meeting for exciting discussions on programmed cell removal from @mounicav07 @broadinstitute and NK-mediated targeting of tumor cells from @MichalSheffer @DanaFarber! Monday April 7th at 3PM on the Harvard Med Quad. https://t.co/uOJiL13B18
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From the March issue: PKN2 Is a Dependency of the Mesenchymal-like Cancer Cell State https://t.co/EyDrssnig8 By Shane Killarney, @kcw00d, and colleagues @Duke_PCB @DukeCancer
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I am honored to talk at the next BDDI meeting, Thank you for inviting me!
➡️Join our next BCDI meeting for exciting discussions on programmed cell removal from @mounicav07 @broadinstitute and NK-mediated targeting of tumor cells from @MichalSheffer @DanaFarber! Monday April 7th at 3PM on the Harvard Med Quad. https://t.co/uOJiL13B18
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➡️Join our next BCDI meeting for exciting discussions on programmed cell removal from @mounicav07 @broadinstitute and NK-mediated targeting of tumor cells from @MichalSheffer @DanaFarber! Monday April 7th at 3PM on the Harvard Med Quad. https://t.co/uOJiL13B18
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Excited to share our latest paper! Dynamic BH3 profiling predicts ALK-TKI response in NSCLC, revealing new therapeutic combos to overcome resistance. Congratulations to Dr. Martín and to all our collaborators @UniBarcelona @CampusClinicUB @IBECBarcelona
https://t.co/FLuw1R11s1
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RESEARCH NEWS🔬🎉 We are thrilled to announce the funding of two groundbreaking research projects focusing on early detection and innovative treatments for children predisposed to cancer. Check out the details in our press release> https://t.co/NFieZwK96T
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1/2 It is not too early to start thinking about the #RadRes2025 Meeting in beautiful #PuertoRico Sept 21-24, 2025 🌞🌴🍹🏖️ Abstract & Submission opens in 2⃣ weeks‼️ The Program is shaping up to be FANTASTIC (prelim program link below ⬇️)🔥🔥🔥
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