C. difficile Papers
@Cdiff_Papers
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Latest from the Clostridium difficile research community. Edited by @nataszahain
Perth, Western Australia
Joined August 2016
A new antimicrobial peptide designed based on Clostridioides difficile IF1 shows broad-spectrum inhibitory activities against C. difficile and other bacterial strains. https://t.co/7kIGgaGKXp
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In @CIDJournal, Pablo Okhuysen, MD, FACP, FIDSA, and colleagues aim to confirm the superiority of ridinilazole over vancomycin on Sustained Clinical Response and recurrent CDI as reported in a Phase II Study. Read: https://t.co/TM6jlH0gkG
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Friday Celebrations! Chenlin Hu, PhD and @GareyKgarey published a review of microscopy methods for C. difficile in Anaerobe! 🔬🦠 Check it out ⬇️⬇️ https://t.co/xlUi9ljaXX
@AnaerobeSociety @UH_Pharmacy
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🌟And the publications keep coming!🌟 Check out our labs most recent work on ibezapolstat activity against MDR C. difficile strains ⬇️⬇️ https://t.co/v47gdM43cc TLDR: IBZ bactericidal activity was similar to the MIC and maintained in wild-type and non-susceptible strains.
journals.asm.org
Clostridioides difficile is a Gram-positive, toxin- and spore-forming obligate anaerobe and the most common cause of infectious diarrhea in hospitalized patients (1). Only two antibiotics, vancomycin...
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🆕️🔥Multicenter cohort study included adults with C. difficile infection @CIDJournal Vancomycin MIC >2 μg/mL in Clostridioides difficile was associated with decreased odds of 30-day sustained clinical response & lower 14-day initial cure rates #IDXposts
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It's not just about age anymore. #Clostridioidesdifficile infection is reaching beyond traditional risk groups. #guthealth #Cdiff
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Pleased to share this publication on vaccine potential of Salmonella against C. difficile in a mouse model: a collaboration with Brian Ward and Ph. D. student Kaitlin Winter @MIMM_McGill and my group @inrsciences @infectiopole. Out in Microbiol. Spectrum:
journals.asm.org
Clostridioides difficile remains a major public health threat, and new approaches are needed to develop an effective vaccine. To date, the industry has focused on intramuscular vaccination targeting...
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Have you seen this new @AmCollegeGastro monograph on microbiome therapeutics? ✅ Essential aspects of methods for analyzing the microbiome ✅ Present and future therapeutics for C. difficile ✅ Non-prescription therapeutics 👉 https://t.co/LGKNgsPW1C
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New findings shed light on the key #microbes that protect against recurrent #Clostridiodes difficile infection and #MultipleSclerosis, pointing to future treatment opportunities with live #biotherapeutics. Read more: https://t.co/Tcm4WuQe97
#Immunology
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Happy to share the latest preprint from the @StadtmuellerLab - an incredible effort by recent PhD student @Sonya31397350! Engineered Secretory Immunoglobulin A provides insights on antibody-based effector mechanisms targeting Clostridiodes difficile
biorxiv.org
Secretory (S) Immunoglobin (Ig) A is the predominant mucosal antibody, which mediates host interactions with commensal and pathogenic microbes, including Clostridioides difficile . SIgA adopts a...
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Fecal Microbiota Transplantation: Information for the Pediatrician https://t.co/TkXfPQrmLF
publications.aap.org
Fecal microbiota transplantation (FMT) involves the delivery of an entire microbial community from a healthy donor to a recipient with the intention of ameliorating or curing a specific disease....
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Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection https://t.co/31f0JTxfzV
nature.com
Scientific Reports - Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection
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Update on Microbiota-derived therapies for recurrent Clostridioides difficile infections, 2023 https://t.co/VylWygEfJ2
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C. Diff: Professors Suggest Inflammation, Not Bacteria Should be Targeted https://t.co/qPlA0HYWQm
#CDiff #ClostridioidesDifficile
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Grat to Jannie and CMAT for this study on bacterial and fungal microbiome interactions in patients colonized or infected with Cdiff. @EurFmt
@CMIJournal @SmitsLab
https://t.co/8d2aCbjaeZ
oaepublish.com
Aim: The bacterial microbiota is well-recognized for its role in Clostridioides difficile colonization and infection, while fungi and yeasts remain understudied. The aim of this study was to analyze...
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The role of gut fungi in #Clostridioides difficile infection https://t.co/eJ8bQdRTJ6
#OpenAccess #mycology #Cdiff
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🆕🔥Our study on C. difficile infections among allogeneic HCT recipients in the framework of the Swiss Transplant Cohort Study🇨🇭@BMTjournal @TheEBMT A short summary 🔽1/5 #IDTwitter
nature.com
Bone Marrow Transplantation - Epidemiology, outcomes and risk factors for recurrence of Clostridioides difficile infections following allogeneic hematopoietic cell transplantation: a longitudinal...
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Doxycycline tied to lower risk for C. difficile in pneumonia patients https://t.co/6XAnpH9BRF
medicalxpress.com
For patients with community-acquired pneumonia (CAP), doxycycline is associated with a reduced risk for Clostridioides difficile infection (CDI), according to a study published online Nov. 1 in the...
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Could a Breath biopsy be used for C. difficile diagnosis in the future? Breath Biopsy and Discovery of Exclusive Volatile Organic Compounds for Diagnosis of Infectious Diseases
pmc.ncbi.nlm.nih.gov
Exhaled breath contains thousand metabolites and volatile organic compounds (VOCs) that originated from both respiratory tract and internal organ systems and their microbiomes. Commensal and pathog...
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