Cambridge FTD
@CambridgeFTD
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The Cambridge Centre for Frontotemporal Dementia and Related Disorders led by Professor James Rowe #JamesRowe #dementia #ageing #FTD #PSP #CBD #Aphasia #PET
Cambridge, England
Joined November 2017
not sure why X gives the "warning sensitive content" - this is a great study, we are proud to support. @racingdementia and @M_Malpetti are *sensitive* to the urgent need for better diagnosis and treatment.
A simple blood test to help detect signs of dementia decades before it develops is being rolled out across the UK by the University of Cambridge. Part of a new study, the researchers are backed by @RacingDementia, the charity founded by Formula 1 racing legend Sir Jackie
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Very proud of the team for showing that restoring GABA can mitigate behavioral & physiological deficits following frontotemporal lobar degeneration .A drug x MEG x PSP|FTD study #PSP #FTD .@wellcometrust @mrccbu @CambridgeBRC @CurePSP @PSPAssociation.
alz-journals.onlinelibrary.wiley.com
INTRODUCTION We examined how abnormal prefrontal neurophysiology and changes in gamma-aminobutyric acid-ergic (GABAergic) neurotransmission contribute to behavioral impairments in disorders associa...
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RT @mrccbu: Henderson et al (@HendersonShalom) analysed connected speech samples from patients with primary progressive aphasia, progressiv….
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RT @braincomms: Rouse et al. report that social- and non-social semantic memory are degraded in frontotemporal dementia following bilateral….
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Wonderful to see your commitment, talent, and effectiveness in science communication being recognised by #WinUKAwards2024 @WomeninNeuroUK with colleagues, students, the public, schools and people with neurological conditions.@mrccbu @Cambridge_Uni.
Having a fantastic time at #WiNUKAwards2024 @WomeninNeuroUK with @BraintasticSci - thank you so much for a lovely evening so far and the "Communicator of the Year" award 🏆🧠. #scicomm
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RT @DementiasUK: Come and join the DPUK team (@DementiasUK ) to find the best blood based biomarkers of Dementia – A new post doc position….
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You don't need high tech to get accurate diagnostic separation of dementia.Simple item-level analysis of low-tech ("paper & pencil") short carer questionnaire gives high accuracy.From Alex Murley @CambridgeBRC .N=2500 people, 11 conditions.@alazassociation
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New in Nat Comms. SiMPill + dSTORM = ultra-sensitive assay inflammasome ASC specks. 95-98% accuracy for PD vs control and Alz vs Con. From @KlenermanLab @PDandHDLab @CambridgeFTD @UKDRI @M_Malpetti @CambridgeBRC .
nature.com
Nature Communications - Lobanova et al. developed a single-molecule immunoassay for quantitative measurements of ASC specks in human biofluids. The authors discovered the combination of ASC speck...
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Social-semantic knowledge in frontotemporal dementia and anterior temporal lobe resection - laterality and severity .=Social- and non–social-semantic deficits highly correlated .=No left vs. right difference in social-semantic knowledge.@mattr19909 @mrccbu.
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Fantastic morning at the #DGN Kongress 2024 Berlin, discussing #SynapticHealth and synaptic biomarkers in blood, CSF, PET and pathology. Thanks to Markus Otto, Patrick Oeckl, Dietmar Thal @lorbarba and @M_Malpetti and the great audience @wbic_cam @DementiasUK
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Do you have post doctoral informatics/biostatistics skills, and want to find the best blood based biomarkers for dementia?.Come and join @DementiasUK at @Cambridge_Uni @CambridgeBRC and the READOUT study team.@alzheimerssoc @AlzResearchUK @NIHRresearch .👇.
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Immunophenotyping dementia. Congratulations @M_Malpetti Alex Strauss John O'Brien and NIMROD group at @CambridgeBRC and collaborators @NicholasAshton Henrik Zetterberg @UCLIoN @UniofGothenburg . AD, FTD, CBS, PSP, LBD. 👉TREM2+ vs classical monocytes correlate with survival.
It is brilliant to see one of the first projects out of my lab now published on @molpsychiatry! . Congrats to Alex, all lab members and collaborators involved - and huge thanks to the participants and families, and all our funders!. Enjoy the read:.
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Great to see @mrccbu and @CambridgeFTD ‘s old friend Luca Passamonti discussing biomarkers in support of therapeutics at #Neuro2024 @CurePSP - now at the “other Cambridge”
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@CurePSP NEURO2024 underway in Toronto with great sessions and panels on genetics, biomarkers, PET, and more - including @M_Malpetti discussing PET assays of inflammation and synapses
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How to recognise it and why it matters. Frontotemporal Dementia with Right Anterior Temporal Predominance - consensus Recommendations of the IWG out now . oh, and the name? answers on a postcard please.#rtvFTD.#esvFTD.#rightSD.@AlzheimerAms #HulyaUlugut.
medrxiv.org
Accurate diagnosis of frontotemporal dementia (FTD) with right anterior temporal lobe (RATL) predominance remains challenging due to lack of clinical characterization, and standardized terminology....
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The prefrontal cortex - it does so much that makes us who we are as people. Inspired? puzzled? want to know more? . The @ESI_Frankfurt have published the definitive guide, to PFC in health, disease, evolution, structure, function, cognition & more. see
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Semantic variant primary progressive aphasia #svPPA (#SemanticDementia). Is it genetic ? . Looks increasingly unlikely, in puzzling contrast to other forms of frontotemporal dementia . See new data from @HendersonShalom @mrccbu and @GENFI1 team.
medrxiv.org
Background Amongst different subtypes of frontotemporal dementia (FTD), semantic dementia (SD, also known as the semantic variant of primary progressive aphasia, svPPA), is the least likely to have a...
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RT @M_Malpetti: It is fantastic to be working together with @CurePSP - an amazing charity, run by brilliant people - to accelerate research….
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Why do people stay well for so many years despite carrying frontotemporal dementia gene mutations from the start? . See @XulinLiu @kamentsve @GENFI1 et al's new study in @alzdemjournals to understand resilience and compensation for preclinical pathology.
alz-journals.onlinelibrary.wiley.com
INTRODUCTION Genetic mutation carriers of frontotemporal dementia can remain cognitively well despite neurodegeneration. A better understanding of brain structural, perfusion, and functional patter...
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RT @PSPAssociation: Our Small Research Grants are open until Friday 15 November 2024. We have previously funded projects such as Dr Ghosh’s….
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