Chris(tine) Spencer
@CSpencerPhD
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Poop excites me more than most people. My tweets are my own.
HTX/SF/TCMI
Joined November 2018
Just published with the #AACR24 presentation, by @DavidSeoMD— Randomized Placebo-Controlled, Biomarker-stratified Phase 1b #Microbiome Modulation in #Melanoma: Impact of Antibiotic Pre-conditioning. https://t.co/6mNN5SJkA3
@CSpencerPhD @JenWargoMD @MDAndersonNews
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💥Very excited to share our latest work in @Cancer_Cell harmonizing WES/RNAseq from melanoma IO datasets to better understand predictors of response to anti-PD-1 therapy. Thank you @parkerici @ScienceAtBMS for supporting this herculean effort in data assembly and analysis
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Honored to be a part of this work now out in @CellPressNews! https://t.co/NJumPJ5P4g
A subset of neutrophils, a type of white blood cell, may aid in eliminating tumor cells, according to a new study led by Dr. Jedd Wolchok (@wolchokj) and Dr. Taha Merghoub (@merghout) of @WCM_MeyerCancer. https://t.co/KADXqPgL0i
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Teiko Bio is presenting next month at #AACR23 on results from the first phase of our partnership with @parkerici on PICI’s RADIOHEAD cohort. Find us in the Biomarkers of Therapeutic Benefit session on Mon, April 17, 9am-12:30pm (section 39, poster 12)! https://t.co/xXzmY6cUBF
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Good morning Minny! Excited to present at the @UMNCancer symposium on #cancer & the #microbiome 💩today!
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(Sorry in advance to all the OG Tab guzzlers) Powerhouse team here addressing an important question on sweeteners & downstream health* impacts (via #microbiome) with this RCT⬇️
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Faecal microbiota transplantation with anti-inflammatory diet (FMT-AID) followed by anti-inflammatory diet alone is effective in inducing and maintaining remission over 1 year in mild to moderate ulcerative colitis: a randomised controlled trial https://t.co/gSlUPlUDm6 v
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Epidemiological studies around the world show that diet influences gut-microbiome profiles even more than people’s genes do, our Director of Informatics @CSpencerPhD tells @Nature
nature.com
Nature - Faecal transplants have helped some people to overcome resistance to powerful immunotherapies. Now dozens of trials are taking aim at the cancer–microbiome connection.
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Great piece by @jeanne_erdmann touching on several aspects of the #microbiome & cancer therapy 🥑🍐💊
How gut bacteria could boost cancer treatments
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Thrilled to share that our HSS-LDA manuscript is out in Cell Patterns! Supervised dimensionality reduction for exploration of single-cell data by Hybrid Subset Selection - Linear Discriminant Analysis (HSS-LDA) https://t.co/KaXaIOdNh9
cell.com
Amouzgar et al. repurpose the classification algorithm, LDA, for supervised dimensionality reduction of single-cell data. Paired with HSS for feature selection, LDA creates intuitive visualizations,...
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Check out the biomarker results from our @parkerici 👑PRINCE👑 trial now live @NatureMedicine- revealing several tumor and peripheral biomarkers for future study in #PDAC
At #ASCO22 Symposium on targeted therapy in GI cancer? Check out the results & biomarker analysis of the phase 2 PRINCE trial on a CD40 agonist, nivolumab and chemotherapy in #PancreaticCancer, led by speaker @laceykitch @parkerici Published today 👉
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Excited to share my fellowship project funded by @ConquerCancerFd and @parkerici
New #JITC article: Ipilimumab alone or in combination with nivolumab in patients with advanced melanoma who have progressed or relapsed on PD-1 blockade: clinical outcomes and translational biomarker analyses https://t.co/Yqw1u2tGN5
@HTawbi_MD @MPostow @wolchokj
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Thank you for your support of this study since it’s inception @PatrickHwuMD!
Food is medicine! So proud to be part of this work led by @JenWargoMD, @CSpencerPhD, and @mcquadeMDLAc demonstrating that dietary fiber can alter the gut #microbiome and enhance the antitumor immune response in #melanoma patients.
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Our Dr. Jennifer Wargo shares key findings of a recent study investigating a high-fiber diet for patients with melanoma treated with immunotherapy: https://t.co/uPrr1Yhq7d
@JenWargoMD @DrLCohen @carrie_d_mac @mcquadeMDLAc #CancerMoonshot #EndCancer
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Also shoutout to all the other co-authors, of which many are working parents that had multiple kids (& 🐶) at home during the pandemic😷🙌🏻. Not an easy task! @VGkrishnanPhD @carrie_d_mac @mcquadeMDLAc @nadim_ajami @JenWargoMD (2/2)
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Happy holidays & glad to finally share the finished product from my graduate work with @JenWargoMD @DrLCohen on the connection of dietary fiber 🥦, the gut #microbiome 💩& #immunotherapy 💉response in late-stage #cancer patients.(1/2)
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Going “live” today for @sitcancer #SITC21. Honored to be talking Host Factors along with other important #Immunotherapy Biomarkers in session 109 just after 2pm EST.
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Excited to parter with @TeikoBio to generate this amazing #CyTOF dataset from our @parkerici AEROSMITH cohort!
Teiko Bio launches with $11.6M Series A financing to advance high-dimensional immune profiling for clinical trials and diagnostics development, including a multi-phase discovery program with @parkerici to accelerate next-generation I/O drug and diagnostics discovery (🧵 1/8)
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Slow clap for this one!👻
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