BurkeLab
@BurkeLabRNA
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Exploring and Exploiting the Functional Capabilities of Nucleic Acids
Joined May 2014
RT @NobelPrize: BREAKING NEWS.The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their….
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Almost all our pubs are collaborations. We just submitted a great piece yesterday. Collaborator wrote to me:. "It's a productive collaboration between your lab and mine. Neither lab alone would have achieved what we got.". and that's why. 😃.
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Structural mechanisms of HIV-1 capsid lattice stabilization.
Oooff! This one tested our limits (7 Xray structs, molec-dynamics simulations, cryoEM, timeresolved imaging, biophys/biochem to elucidate how mutations enhance/reduce HIV core stability, thus impairing infectivity & how 2ndsite mutations rescue infection.
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RT @SomaLogic: The FDA recently approved the second RNA aptamer-based drug. Aptamers offer powerful opportunities for drug discovery and de….
nature.com
Nature Reviews Drug Discovery - Discover the world’s best science and medicine | Nature.com
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Keeping my distance from 'X' these days. Hence the silence. What alternative social media platforms are ppl using these days? . What makes it 'better' (apart from absence of the distasteful parts of 'X')?.
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RT @HoebartnerLab: #SAMURI is a new #ribozyme for RNA-catalyzed labeling of RNA. It uses a new cell-permeable SAM analogue and generates a….
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I think I’ll spend tomorrow ‘Writing.’.
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RT @NobelPrize: Happy pi approximation day!. Today's date, 22 July, can also be written as the fraction 22/7, which is equal to 3.14285714,….
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RT @SaurjaDasGupta: @BurkeLabRNA A Biochemist and a Geologist walk into a bar and try to solve the origins of life problem. Bartender to t….
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RT @BiochemPhD: @ATinyGreenCell @O_Borkowski @davesnetvault Very cool work. Reminds me of a paper from @ProfTomEllis lab that I believe was….
pubs.acs.org
RNA–RNA assembly governs key biological processes and is a powerful tool for engineering synthetic genetic circuits. Characterizing RNA assembly in living cells often involves monitoring fluorescent...
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Great idea! @eternagame teaches humility, since designs can easily get tangled up in alternate folds!.
Excited to share how I use @eternagame to teach students about #RNA folding & function in my @NSF CAREER funded, CURE-style Chemical Biology lab course!.
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This was a fun test for detecting real/fake news. I scored 18/20 on MIST, better than 81% of the US population. Thanks @JosephYesselman !. What is #YourMIST? 🧐 #misinformation #fakenews.
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RT @HoebartnerLab: Expanding the scope of RNA-catalyzed reactions @Uni_WUE. This work #AngewandteVIPs shows how to….
onlinelibrary.wiley.com
The methyltransferase ribozyme (MTR1) catalyzes site-specific alkylation of a purine nucleobase to initiate the formation of the 5-amino-4-formylimidazole nucleobase analogue, which serves as the...
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PCE3 seminar this week!. Origins of metabolism. and. Organic cofactors talking with mineral surfaces about electrons.
The next episode of the PCE3 Seminar series is this week!.Tune in to hear about Oceans and Origins with Jessica Weber and Katherine Dzurilla from the JPL.
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Diagonal bike lane. There’s an innovation I could do without.
I’m a proud SF cyclist. Always will be. But this new diagonal bike lane on 23rd & Valencia is a failure and dangerous. I was recording because I have a genuine question for @sfmta: what do you expect to happen when the light turns green?
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