Behzad Karkaria
@BezKarkaria
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Joined March 2021
It's World AMR Awareness Week! 🌍💊 At Bactobio, collaboration is key to what we do. We're proud to partner with key stakeholders to fight AMR and discover novel antimicrobials. Watch our video with @MicrobioSoc to see how we're making a difference. #WAAW23 #StopSuperbugs #AMR
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A little thread on our new preprint https://t.co/35H2dr9Y5K We created a bacteriocin delivery system that can be used for microbiome engineering and tackling antimicrobial resistance. @cssb_lab members Jack Rutter, Linda Dekker, @ajfedorec and @ChaniaNClare. Funded by @EPSRC
biorxiv.org
Bacteriocins are antimicrobial peptides that are naturally produced by many bacteria. They hold great potential in the fight against antibiotic resistant bacteria, including ESKAPE pathogens....
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Today we're proud to announce our latest £6Mn raise to help us discover novel antimicrobials. Funds will support our mission to help turn our captured biodiversity into commercial products. ▶️Read more here: https://t.co/pa0X5vADHy
#biotech #fundraise #announcement
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Great timing! first author @paula_jouhten will present this tomorrow at #EMBLEvoEco
EvolveX: a new algorithm for model-guided design of chemical environments for targeted #adaptiveevolution. Here, applied to evolve a wine yeast strain for increased aroma secretion ➡️ https://t.co/CJyej7Jrx8
@kiran_r_patil @MRC_TU #evolution 🍷
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Now state-of-the-art advances on metagenomics-driven metabolic modelling with Francisco Zorilla @metagenomez @kiran_r_patil @Cambridge_Uni @MRC_TU #COBRAcon2022
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Hi, today we are happy to announce the next edition of the OpenBioML Journal Club. Join us next Friday (September 30th) at 9 PM CEST as @NeythenT presents "Deep Reinforcement Learning for Optimal Experimental Design in Biology" ( https://t.co/MCHlxvXrDm) and its broader context.
biorxiv.org
The field of optimal experimental design uses mathematical techniques to determine experiments that are maximally informative from a given experimental setup. Here we apply a technique from artific...
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Gut bugs can be engineered to act with spatial precision in the mammalian gut. Nina Short, @KlondikeClare, and I recently put together this mini-review. 👏on first output from the Riglar lab! Lots of exciting applications emerging in this space across research and #biotech!
New Research: Achieving spatially precise diagnosis and therapy in the mammalian gut using synthetic microbial gene circuits https://t.co/ETpTymFv2V
#bioengineering #biotech
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Check out the new review from Jack Rutter, Linda Dekker and @KimberleyAOwen @cssb_lab on microbiome engineering and human diseases https://t.co/GZwTOLkfx8 If you are interested in this then fill out our survey on microbiome engineering and cancer! https://t.co/0o1aUnv8cY
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❗️Another week, another PhD student has come to my office in tears as they can’t afford to live in London on £18k. And this is before the price cap increase. @UKRI_News this time - can I ask what you are doing to support the next-generation so there is a next-generation?! Pls RT
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“New research finds that chaos plays a bigger role in population dynamics than decades of ecological data seemed to suggest.”
quantamagazine.org
New research finds that chaos plays a bigger role in population dynamics than decades of ecological data seemed to suggest.
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A response that does not address the very real needs of current research students. The argument that current student support cannot be improved by UKRI in case it jeopardises the ability to fund as many future students is very difficult to support.
We have published our response to an open letter from postgraduate research students on inflation and the cost of living. The reply is on our website here:
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We have a postdoc position available in our lab. Very happy to chat to anyone interested about life in the lab
Postdoc position available in the CSSB group at UCL to work on the intersection of biocomputing, microbial communities and engineering biology. Deadline 01.08/2022. Get in touch if you would like more info or to speak to group members.
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Application deadline soon! Fantastic opportunity for training in emerging concepts and tools for deciphering metabolic interactions in microbiomes https://t.co/JkzCKqx0UX
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Great to see this new work out from @NeythenT in @cssb_lab. Joint work with @bpingalls @NateBraniff. We essentially recast Optimal Experimental Design as a reinforcement learning problem.
Deep Reinforcement Learning for Optimal Experimental Design in Biology https://t.co/H3Ir2z8kEE
#bioRxiv
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#machinelearning and #DataIntegration for uncovering protein-binding potential of natural compounds. Fantastic work by Vinita from our lab @MRC_TU in collaboration with @TypasLab @embl & Kaustubh Patil @fz_juelich #drugdiscovery #toxicology
https://t.co/YGzJ1Td6Ku
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📢⛅️New preprint on gene essentiality Machine learning + Flux Balance Analysis achieves near state-of-the-art accuracy in E coli, with minimal assumptions on optimality of deletion strains. https://t.co/GMyAHquxHZ
@SynthSysEd @ancAtEd #qbio #synbio
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KEMET is out!!! KEMET is thought for your MAGs with three main aims in mind: map microbial functional potential, identify missing orthologs with HMM profiles and increase the quality of draft GSMM. @palu_matteo
@LauraTreu
@campanarostef
@DiBio_UniPD
https://t.co/NASQrjIsJC
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This is a thing we wrote. We argue that new physics/engineering/statistics/AI tools are needed to accelerate translation of the human microbiome. https://t.co/8530WM1ZXd
openaccessgovernment.org
Prof Chris Barnes & Dr Jack Rutter share a future vision for microbiome engineering - harnessing the microbiome’s role in health & disease
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Dear microbial synthetic biologists: Submit your abstracts to ISME 18 #ISME18! (Lausanne, 14-19 Aug 2022). David Riglar @driglar and I are hosting a session on “Synthetic biology in microbial ecology”. Abstract deadline: 1st of April. https://t.co/0K2p9xHBDj
@ISME_microbes
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Check out our collaboration with the @RalserLab regarding auxotrophies and drug tolerance in microbial communities!
Interested in antimicrobial drug tolerance? We show that auxotrophs exist within virtually all microbial communities, and increase their drug tolerance by stimulating metabolic interactions. https://t.co/VIfCjW1nF2
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