Chassaing Laboratory
@BenoitChassaing
Followers
2K
Following
582
Media
105
Statuses
747
Laboratory at @institutpasteur working on Microbiome-Host interactions. In gut I trust. Bugs are my friends & tweets are my own
Paris, France
Joined August 2013
Are you interested in nutrition care for #IBD? Then don't miss the 3rd Annual Nutrition & IBD Education Session 👩🎓 @GimdGold, @BenoitChassaing, Sydney Anzellotti, Kristen Nicolai, @pedsIBDdoc, @GIdietitian & @nhaskeyRD 👉 Register for free here: https://t.co/WP8qvgCPL5
0
3
2
This work has now been published in @NatureComms - congrats again @Claradelaroque
nature.com
Nature Communications - Here, Delaroque et al. show that maternal intake of dietary emulsifiers alters offspring microbiota early in life, which, associated with perturbation of goblet cell...
🦠🍦Delighted, with @ClaraDelaroque, to share our new preprint on an exciting story reporting the impact of maternal additives intake on offspring’s #microbiota and health, with a crucial role played by #Goblet cells ! A thread 🧶
0
0
7
#GUTImage from the paper by Rytter @HeloiseRytter et al on "In vitro microbiota model recapitulates and predicts individualised sensitivity to dietary emulsifier" via https://t.co/TvnuuS7Grf
@BenoitChassaing @institutpasteur @Inserm #Emulsifiers #Diet
0
4
11
Excited to announce results of our #ADDapt trial After 6 years and the help of 154 people with #CrohnsDisease we prove that restricting #emulsifiers improves disease Award winning presentation from @AaronBancil at #ECCO25 Excited for next steps to help people with Crohns
33
120
368
7/ and thanks to our collaborators and participants who made this possible! 🙏 @GSUIBMS @GSU_Research @IHU_Infiny @PCMicrobiome @ClementLab @PeyrinBiroulet Read the full study here: 🔗
gut.bmj.com
Background Non-absorbed dietary emulsifiers, including carboxymethylcellulose (CMC), directly disturb intestinal microbiota, thereby promoting chronic intestinal inflammation in mice. A randomised...
0
2
5
6/ A huge thank to @HeloiseRytter for her tireless effort and our funders @ERC_Research @AgenceRecherche @afaCrohnRCH @fondationaveni @Inserm @InstitutCochin @institutpasteur
1
0
1
5/ 💡 Implications: This study opens the door for microbiota-based dietary guidance. Imagine knowing how your gut will react to specific foods before eating them! Personalised nutrition is coming ! 🧬🦠🧬🦠
1
0
0
4/ Why it matters: Personalised nutrition is here! 🥗 CMC-sensitive microbiotas, when transplanted into mice, triggered colitis 🔥 under CMC exposure. Hence, baseline microbiota 🧬 is key to understand and predict the impact of emulsifiers!
1
0
0
3/ ✨ New finding: We developed an in vitro gut microbiota model that: ✅ Replicates individual responses to CMC ✅ Predicts who might be sensitive—based on their baseline microbiota metagenome We could predict sensitivity status before exposure, just through microbiota analysis
1
0
0
2/ Background: Dietary emulsifiers such as carboxymethylcellulose (CMC) disrupt the microbiota and promote chronic inflammation in mice. In humans, our previous trial (FRESH https://t.co/cAQg8YVUmx) found that not everyone is equally sensitive to CMC. So why such difference? 🤷♀️
pubmed.ncbi.nlm.nih.gov
These results support the notion that the broad use of CMC in processed foods may be contributing to increased prevalence of an array of chronic inflammatory diseases by altering the gut microbiome...
1
0
0
1/ 🚨 New study alert! 🚨 Can your gut #microbiota predict how you'll react to dietary emulsifiers? 🤔 Our lab's latest work explores this question using an in vitro microbiota model. 🌟 Published in @gutBMJ! 🧵👇 https://t.co/VTVu6wZGXr
gut.bmj.com
Background Non-absorbed dietary emulsifiers, including carboxymethylcellulose (CMC), directly disturb intestinal microbiota, thereby promoting chronic intestinal inflammation in mice. A randomised...
1
11
34
Work from @melissa_kordahi @NoemieDaniel2, thanks to the support from @ERC_Research @Inserm @institutpasteur @InstitutCochin @AgenceRecherche @afaCrohnRCH @FRM_officiel
0
0
4
Mucus-associated bacteria are key 🦠🦠!!! Here, we report that mucus-penetrating bacteria are sufficient to drive chronic inflammation 🔥❤️🔥and metabolic dysregulation. Can we target them to prevent diseases ? 💉💉
tandfonline.com
Metabolic syndrome is, in humans, associated with alterations in the composition and localization of the intestinal microbiota, including encroachment of bacteria within the colon’s inner mucus lay...
1
16
52
Friends and colleagues, I’ve moved all activities related to my lab’s research on microbiome-host interactions @institutpasteur to BluSky. Excited for the opportunities this platform brings to connect and collaborate!
0
0
3
No.1 in our most impactful articles of 2024 (Altmetrics) This REVIEW on ultra-processed foods and food additives in gut health and disease by @ProfWhelan, @AaronBancil, James Lindsay & @BenoitChassaing
https://t.co/B1oh6GKecx
#sharedit link:
nature.com
Nature Reviews Gastroenterology & Hepatology - In this Review, Whelan and colleagues summarize and discuss evidence for the effects of ultra-processed foods and food additives on gut health and...
3
51
142
New international consensus statement on microbiome testing in clinical practice relevant for scientists and healthcare professionals From @gianluca1aniro, @dorejoel, @mcarmen_collado, @BenoitChassaing, @h_sokol et al. via @LancetGastroHep: https://t.co/7kKM1bkuHj
0
17
48
👏Félicitations à @BenoitChassaing, chercheur à l’Institut Pasteur, lauréat de l’appel à projets PEPR Systèmes Alimentaires, Microbiome et Santé, pour son projet « Interactions microbiote intestinal – additifs alimentaires : cartographie et mécanismes en jeu en santé humaine ».
0
5
37
2024 was such a whirlwind of fun, chaos, and epic moments — 10/10, would live it again (but with few naps). Grateful to work with the most incredible lab mates. Let’s make 2025 even more amazing ! 🚀🙌 🦠🥼🧪#BringOn2025 #InPoopWeTrust
0
0
23
🎉 Félicitations à @BenoitChassaing, chercheur à l’Institut Pasteur affilié à l'@Inserm, lauréat du Prix MFP de la @FondationAvenir pour ses travaux sur le rôle des bactéries du mucus intestinal dans le cancer colorectal. Une avancée majeure en recherche médicale !
0
12
43
ERC grants are ALWAYS a team effort - so a huge thank to past and current lab members @HeloiseRytter @Claradelaroque @melissa_kordahi Chloé Robert @NoemieDaniel2 @BonazziErica Maeva Duquesnoy @QuentinLamy2 Kenza Mourji @CharleneDauriat @EvaChatonnat @SabrineNaimi
1
0
11