Alexander M. Wolf
@AlexanderMWolf7
Followers
348
Following
1K
Media
128
Statuses
3K
Scientist. Father of 5. Wrote "The tumor suppression theory of aging"&"Rodent diet aids and the fallacy of caloric restriction"
Dettighofen
Joined December 2021
Instead of always greedily asking for more money, the aging research community might also show humility and reflect on why Ellison stopped supporting aging research. He certainly didn't run out of money. He's just far less gullible than aging researchers would like him to be.
Larry Ellison, briefly the world’s richest man this week (until his Oracle shares slipped back slightly and @elonmusk regained the tip spot) is a great case in point: he funded the Ellison Medical Foundation…but only with a fraction of his net worth!
0
0
0
@jpsenescence As @jpsenescence has thankfully pointed out, this post of course links to the wrong review. The post with the corrected links is here: https://t.co/2s72whEz9X
This time with the right screenshot and link to the 2025 review, not an old one! I feel honored by this beautiful review by @jpsenescence of the constraints cancer risk imposes on aging. Important and welcome support for the tumor suppression theory of aging.
0
0
0
@jpsenescence And once more, the link to the tumor suppression theory of aging. https://t.co/ge2GFCn49J
0
0
0
@jpsenescence And here's the link to the review, also in @NatureRevCancer, but from August 26th 2025, not from 12 years ago. https://t.co/0sVQit8DlL
0
0
0
This time with the right screenshot and link to the 2025 review, not an old one! I feel honored by this beautiful review by @jpsenescence of the constraints cancer risk imposes on aging. Important and welcome support for the tumor suppression theory of aging.
5
1
6
@jpsenescence @NatureRevCancer That is of course the wrong link, the right one is this: https://t.co/0sVQit8DlL
0
0
0
@jpsenescence And the tumor suppression theory of aging. https://t.co/ge2GFCmwkb
0
0
0
I feel honored by this beautiful review by @jpsenescence of the constraints cancer risk imposes on aging. Important and welcome support for the tumor suppression theory of aging.
4
3
12
Dead from cardiac arrest at age 49.
Mike Mentzer was the most controversial bodybuilder of all time. • Perfect score of 300 in Mr. Universe • Creator of the "Heavy Duty" system • Advocated intensity over volume for explosive gains Here're 7 of his most powerful training principles you need to know:🧵
0
0
1
Child allowance in Germany will increase by 4 Euros (~1.5%) per kid in 2026. Pensions will rise ~40 Euros (~3.37%) in 2026 on average. This underscores the enormous sacrifices Germany is willing to make for it's future generations. https://t.co/9jmaQurXSp
@BirthGauge Having children ist just the most stupid thing to do in modern social security systems. Sacrifice your time, wealth, job & freedom to have kids that will have to pay the pensions of your childless peers? Too few are that (senti)mental. Nothing will change until kids pay off.
0
0
1
"Services are delivered through a tiered membership structure, which ranges from blood biomarker testing packages priced at AU$499 up to more comprehensive longevity services costing AU$2,999 per year." https://t.co/kkSMY5XaWi
longevity.technology
Everlab to advance preventive health model with AI-driven health intelligence and advanced diagnostics at its core.
0
0
0
"Longevity medicine" might make you worried, sick & poor. So realize that what empties your wallet fills the wallet of someone else & might influence what they tell you. In Germany, a good criteria is: if stingy government insurance pays for it, it's useful. If not, maybe not.
4
0
5
Now that AI has figured out its surname, let's hope it will solve death next.
0
0
3
"Finally, although the models were adjusted for important confounders such as educational attainment and income, we cannot rule out the risk of residual confounding from unmeasured confounders" Like people with tattoos going out more because they want to show their tattoos!!!
A large Swedish study (n=11,905) found tattooed people had a +18% risk of malignant lymphoma. 📈 Risk was +81% in the first 2 years after tattooing 🧬 Laser-removed tattoos were linked to a +199% risk (nearly 3x), possibly from the breakdown of toxic compounds
0
0
2
I'm sorry, but in Fig. 2b of "Limited cell-autonomous anticancer mechanisms in long-lived bats", two supposedly different mice "M. lucifugus SV40 LT only" & "E. spelaea GFP" look awfully similar to me. Photo's not the same, but the mouse seems to be. https://t.co/c6SbwyM9vr
nature.com
Nature Communications - Cancer incidence is rare in long-lived bats. Here the authors find that although bat fibroblasts express telomerase and require only two oncogenic hits for malignant...
1
0
2
Seriously? It really illustrates the remarkable cluelessness & desperation of Calico & geroscience when an IL-11 mAB for fibrosis & advanced malignancies becomes an "anti-aging asset". And a weight loss antibody "the biggest concrete win in the aging space in the past 30 years".
Calico making a big push for advancing what I'd argue is the biggest concrete win in the aging space in the past 30 years. For those not up-to-date, for decades the only meaningful wins the lifespan-extension longevity world had were (1) caloric restriction and (2) rapamycin.
1
0
5
Laura Niedernhofer also came to my poster yesterday. We both agree (and @schumacherbj as well, I guess) that DNA damage is likely the most important causal driver of aging. We just might disagree somewhat about the evolutionary interpretation of the response to DNA damage.
0
0
1
Very nice review underscoring the universality of cancer as a disease & its ubiquity in both domesticated and wild animals. This should help to dispel the myth that aging & cancer are "artifacts of domestication", & that animals "in the real world" don't get it. @StevenAustad
Studying cancer across species can reveal new ways to understand and potentially treat cancer. Together with leading experts, we now explain why this field matters more than ever. Full text👉 https://t.co/BLlmiQVyI2
@ImmunoConcept @WicaneResearch @MathieuGiraude3 @ATJCagan
0
0
3
Those who have seen my posters in recent years will recognize the main figure. Publishing this is overdue, together with a deep dive into the history of the idea of a strong cancer-aging trade-off, and why this idea was so enthusiastically "forgotten".
1
0
2