Chien-Hsiung Alan Yu
@AlanCHYu
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Head of Neuroinflammation Laboratory | ALS-FTD | The Florey Institute of Neuroscience and Mental Health | NeuFlam Lab 🧠
Melbourne, Victoria
Joined September 2018
What do we know about inflammation? 🧠 "It’s clear that if we can regulate the immune system, we may be able to develop new treatments for managing inflammatory diseases." Read the piece by Dr @AlanCHYu, Head of our Neuroinflammation Group: https://t.co/1eEKJjbnRY
#neuroscience
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Excited to share the pre-print of our latest work on the AD resilience mutation Christchurch, elucidating a central role of cGAS-STING and IFN suppression! Congrats to first authors @naguib_sarah @EiRuTorres @ChloeLopezLee
biorxiv.org
The Christchurch mutation (R136S) on the APOE3 ( E3S/S ) gene is associated with low tau pathology and slowdown of cognitive decline despite the causal PSEN1 mutation and high levels of amyloid beta...
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The Scientific Seminar continues next week with Dr @AlanCHYu from The Florey in Melbourne. Dr Yu will share exciting results, identifying a key inflammatory pathway causing MND progression. 12pm AEST on Tues 23rd April. To learn more or to register: https://t.co/7ITaphY74k
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Now online! Human iPSC 4R tauopathy model uncovers modifiers of tau propagation
cell.com
Robust and scalable iPSC-derived human neurons are generated to model 4R tauopathy phenotypes. CRISPRi-based functional genomic screening in this model identifies genetic modifiers of seeding-induced...
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So happy to see our review online in @NatureCellBio - “Lipid droplets and cellular lipid flux” - lead by super star grad student @alymathiowetz! Droplet biogenesis/ turnover, contacts and lipid transfer, roles in lipotoxicity / cell death, and more! 🎉
nature.com
Nature Cell Biology - Mathiowetz and Olzmann review our current understanding of the mechanisms of lipid droplet biogenesis and turnover, the transfer of lipids and metabolites at membrane contact...
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STING signaling in the brain: Molecular threats, signaling activities, and therapeutic challenges @NeuroCellPress
https://t.co/oUynAIn1ZH
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A PhD position now open in the NeuFlam Lab #TheFlorey. Join us to explore the causes of neurodegneration through the lens of innate immunity. If interested, please contact @AlanCHYu or alan.yu@florey.edu.au
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We are recruiting a full-time research assistant to the @NeuFlamLab at @TheFlorey. If you are passionate in neuroinflammation in ALS-FTD and looking for a future PhD career, please contact me. https://t.co/XksQ7Vl5If
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Delighted to host Dr Kaoru Yamada from the University of Tokyo, giving a seminar, science mingling and training @NeuFlamLab. Truly collaborative research supported by @nhmrc @AMED_officialGL @MND_RIA @TheFlorey 🇦🇺🇯🇵
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Had an amazing time at the Australia & New Zealand MND Research Symposium 2023. Great programs, networking and more big ideas back to the lab to end ALS 💪
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Together with an amazing team of CIs, Dr Kaoru Yamada, @shazanfar @rkhyip @SiMingMan1 and @turnerMNDlab
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Plenty of MND-related content; Clearance of Extracellular Tau by the Glymphatic System: Implications for Alzheimer's disease 10:00 am - 11:00 am 1 December 2023 Dr. Kaoru Yamada - Assistant Professor, University of Tokyo https://t.co/89i5UQ9w3n
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Australian science has lost a shining star. One of its brightest minds, and by far its biggest heart. A beautiful man. x
abc.net.au
The molecular biologist spent more than a decade researching a cure for motor neurone disease (MND) following the deaths of four members of his family.
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We are grateful to have this opportunity to share our thoughts and strengthen the MND research with our community 💪 @MNDVic @TheFlorey #endALS #EMCR The MIROCALS trial and beyond
mnd.org.au
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FINAL CALL🎙️ for registration to this fully loaded spatial omics Symposium. We have exhausted our 200+ in-person capacity but there are still limited tickets for online attendance. Get in quickly! *Register to receive program* https://t.co/Wko2SIJs4u
#spatialomics
eventbrite.com.au
Join us for a full day symposium exploring everything spatial!
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I highly encourage anyone who is eligible to consider applying for this @EMBLAustralia PhD course. As one of the participants of the inaugural program back in 2013 I can say it was an amazing experience and I'm proud to have networks and friends from that course a decade later 😀
Join the #EMBLAPhD Course & make connections to last a lifetime 🌟 Connect with brilliant peers from all over Aus, who will support you every step of your PhD journey. Gain invaluable real-time feedback, expand your network & uncover an exciting future. https://t.co/IZOEkxbJnH
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📢We're hiring!📢 The Florey is looking for outstanding individuals to join our dedicated group of researchers and support staff in a number of positions. 🧠Be part of our world leading team advancing brain research. Find out more about Florey careers👉 https://t.co/rtQ8n9SkqA
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Amazing and talented PhD poster presentation by @laohamonthonkul at the ADRF 2023. The runner-up award on investigating the link between tauopathy and lipid stress and of course neuroinflammation. #ADRF2023 #proudsupervisor #theflorey
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