Henrik Ahlenius
@AhleniusHenrik
Followers
610
Following
1K
Media
37
Statuses
267
Associate Professor, Stem cells, Aging and Neurodegeneration lab @Lund_Stem Cell Center @Lunduniversity #stemcells #reprogramming #crispr #LundSCC
Lund, Sverige
Joined October 2019
Dr. Elly Hol's team at @UMCUtrecht found that mutations in GFAP can severely affect neural #organoid development through altering lineage commitment in embryoid bodies. GFAP plays a role as an early modulator of neurodevelopment. 🧠 https://t.co/2uIfLQTXmZ
0
4
10
Preprint alert! Happy to share our latest work, in which we identify Flunarizine as an inhibitor of astrocyte reactivity with therapeutic potential in glioblastoma (GBM). Details in thread: https://t.co/Mcg08g3OCj
biorxiv.org
Radiotherapy is part of the standard-of-care for glioblastoma, yet tumors invariably recur as incurable lesions post-treatment. Recent studies suggest that radiation-induced astrocyte reactivity...
1
1
4
#GLIA2025 Check posters T21-004A and T24-013B The team will be represented by Alicja presenting our AD modeling by direct conversion of fibroblasts to astrocytes and neurons, and Enrico will present our inducible BRAF fusion iPSC and cerebellar organoid model of astrocytoma.
0
1
2
Want to decode #cancer & #autism with organoids, stem cells & genomics? We’re hiring PhD students @DKFZ via the fully funded International PhD Program! 🌍 Heidelberg 🔗 https://t.co/NrYUn9RdFz
#PhDopportunity #CancerNeuroscience #Genomics
2
41
111
Very happy and excited that our project together with Johan Bengzon were chosen for BRIDGE Sweden. This support will be instrumental to further develop our potential gene therapy for GBM towards clinical trials
mynewsdesk.com
Four pilot projects will receive dedicated support to accelerate the commercialization of their specific biological product through BRIDGE Sweden. The...
3
1
11
Happy to have contributed to this study. Wonderful consortium with excellent science, collaboration and people! Congratulations to everyone involved!!
🎉Excited to share our latest paper in @GLIA_Journal led by my brilliant student @ZMatusova, in collaboration with amazing international partners!🌍 📄 Aberrant neurodevelopment in human iPS cell-derived models of Alexander disease https://t.co/FgnhDtXPdO
@IBT_CAS @BIOCEV_science
0
4
9
What fuels a lifetime of discovery? Prof. Olle Lindvall, a jubilee doctor at @lunduniversity and pioneer in brain repair, reflects on 50 years of neuroscience. Discover his journey from student to neuroscientist and his advice for future researchers ⤵️ https://t.co/5VfXLa3eWY
stemcellcenter.lu.se
Lund University. Olle Lindvall’s early academic interests did not suggest a future in neuroscience. “Before I took my high school exams," he recalls, "Biology was not on my radar. I was more intere...
0
4
7
Next piece in the puzzle. PhD student Jonas Fritze performed scRNAseq of neuroblasts during aging. We find that excitatory progenitors decrease faster than inhibitory and that some neuroblasts acquire an immune response signature. #neurogenesis #stemcells
frontiersin.org
In the adult murine brain, neural stem cells (NSCs) reside in two main niches, the dentate gyrus (DG), and the subventricular zone (SVZ). In the DG, NSCs giv...
0
1
8
It's been 6 years that we developed our iAs protocol @AhleniusHenrik and it is really rewarding to see it being used in such an amazing work!
Contributions of genetic variation in astrocytes to cell and molecular mechanisms of risk and resilience to late onset Alzheimer's ... https://t.co/tLbz5x8299
#biorxiv_neursci
0
2
16
I will be attending #AAIC2024 virtually and presenting our work on CRISPR engineered pluripotent stem cell based models of neurodegeneration. Check out the Featured Research Session (4-35-FRS-B (ID: 12417)) on July 31st!
0
1
3
Wrapping up #ISSCR2024 with a great @Lund_Stem Reunion/Mingle yesterday and some fantastic talks today. It’s been a great meeting and super fun connecting with old and new friends. Lots of new inspiration and feedback on our research. Next up #AAIC2024
2
2
18
@Frenkez @Canals_Lab TODAY: check out @EnricoPracucci poster 377 and how we explore reprogramming to astrocytes as a potential therapy for glioblastoma
0
0
1
2
1
10
Fantastic time at #ISSCR2024 meeting old and new friends! If you are interested in discussing the essential role of suppression of plasticity in reprogramming, development, and disease, please join me at my poster #376 tonight 🧬🧫🦀
1
4
31
@Frenkez TODAY: Visit poster 224 to chat with Oskar Zetterdahl ( joint PhD student with @Canals_Lab ) about tagging SNCA in iPSCs for tracking aggregation in LSDs
1
1
4
TODAY: come visit poster 571 and chat with @Frenkez about our crispr engineering of iPSCs for conditional expression of transgenes and mutations with applications in disease modeling
1
0
2
The lab will be at #ISSCR2024. Check out our posters: number 224, 377 and 571. Also, feel free to reach out if you want to chat about reprogramming, disease modeling or anything astrocytes. See you soon!!
1
5
26
📣Join us at @Lund_Stem! The Lab of Epigenetics & Chromatin Dynamics, led by @ch_douse at @lunduniversity, is #hiring a Lab Manager for a @ChanZuckerberg-funded project on #epigenetic mechanisms in brain development & degeneration. Apply by May 24! ⤵️ https://t.co/EhVXI3EXUc
0
1
8
We are recruiting! We are looking for new members (postdocs and/or bioinformaticians) to join our team. Translational projects on neuroinflammation, transposable elements and single cell analysis. Email or DM me for more info! @Lund_Stem Please RT! https://t.co/YZiOM2GROs
molecular-neurogenetics.lu.se
Lund University. Short introduction to Johan Jakobsson's research Our lab is interested in transposable elements and how these viral-like sequences influence human brain evolution, neurodegenerative...
0
31
36
Great PI, Project and Place! Apply👇
🚀 Make an impact and kickstart your career! Join our lab @DKFZ PhD program to study brain disorders, #cancer, and cell fate plasticity. Apply by May 15 to launch your #ScienceCareer. For details, visit our site or DM. Please RT! @phdcareers @UniHeidelberg
https://t.co/gFKK842AWL
0
1
4