🚨 Just out today (online)! 🚨. Our results show that a common argument against #QALYs (based on the use of subgroup analyses) is not justified with empirical data. With co-authors: Leah Rand, @wbfeldman, and @akesselheim from @PORTAL_Research, @BrighamResearch, @harvardmed.

Always a super interesting read! . Notably, amongst the top 20 CEOs, average compensation was greater than $30 million. Total compensation for the top 20 CEOs was more than $600,000,000. Also notable that there is only one woman amongst the top 20. via @AndrewE_Dunn/@endpts.

Just out! The new guidelines from the Canadian Patented Medicine Prices Review Board (PMPRB) have finally been released. Changes to take effect as of January 2026. #hta #drugprices.

A little work to make one of the local #Squamish trails a bit more friendly to those riding adaptive mountain bikes.

RT @Yale_CRRIT: These 1–2 month reviews may be dangerously fast—even with a fully staffed FDA. But as @jsross119 told both @STATNews and….

The clinical aspect & decision aside, it's problematic for health systems that BioMarin priced Brineura at $1 million. If companies didn't charge these prices, decisions are easier & less restrictive. Note: Brineura's net sales in 2024 were $170 million.

'A 2023 analysis of more than 20 million deaths across the world found that hot days and days with bad air quality both resulted in higher-than-normal mortality rates. But periods in which heat and pollution are combined were even more deadly.'. via @nytimes.

Looking for a recent paper that reports on HRQoL via EQ-5D-5L/3L scores, that specifically reports on the each of the domains/levels of the EQ-5D. Preferably in a chronic disease, and also preferably US-based (but not necessary). Anyone? @EuroQol . #healtheconomics #hspr #QALYs.

RT @oncology_bg: The last video lecture on the topic of surrogate endpoints is now live on Medscape Skills Lab series. This one addresses s….

Super interesting story about Novo Nordisk and their Canadian patents. '. Novo did file a patent there for semaglutide. but the last time they paid the annual maintenance fee on it was 2018!'.

RT @HarvardCCHANGE: Our fellow Dr. Catharina Giudice shares in @Nature how repeated exposure to extreme #heat can lead to kidney failure.….

Living in a community that currently has an active and out of control wildfire, this research is incredibly timely. An important new study from authors at the @CDCofBC. via @Nature_NPJ .

RT @ihspr_isps_cihr: 🚨 Less than a month left!.The Health System Impact Fellowship is now accepting applications. There's incredible intere….

Great and engaging panel discussion about the future of the Inflation Reduction Act by @bnrome, @DusetzinaS, and Alyson Bancroft (@P4AD_) (moderated by Chris Cai)! . #ARM25 @PORTAL_Research

Really interesting discussion about climate change and health care at #arm25 with Betty Bekemeier, @jgreene2, @DrSoniaAngell, and Winnie Chi.

Presenting some work on spending associated with drugs for ultra-rare diseases at the @AcademyHealth Annual Research Meeting!. #arm25 @PORTAL_Research

Chris Cai from @PORTAL_Research presenting on private equity acquisitions of health care delivery organizations at the @AcademyHealth Annual Research Meeting. #arm25

Opening plenary underway with @aaronecarroll at the @AcademyHealth Annual Research Meeting. #arm25

This narrative is dangerous and has/will lead us to poor decision-making about paying for cancer therapies. Important research by @kjmeetswrld (including @oncology_bg, myself, and others) has already shown this not be the case. #hta.

On the way to the @AcademyHealth Annual Research Meeting with Jerry Avorn in my ear. #arm2025 @PORTAL_Research

Looking forward to attending my first ever @AcademyHealth Annual Research Meeting with fellow @PORTAL_Research members @bnrome and Chris Cai!. I'll be presenting some work on spending associated with drugs for ultra-rare diseases on Sunday evening. See you there!. #arm2025