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zhenlab

@zhenlab_Toronto

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We study the development and function of the C. elegans nervous system

Toronto
Joined April 2021
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@zhenlab_Toronto
zhenlab
3 years
can now view synaptic connections and synapse sizes in 3D. Just click on the neuron name. Currently, only the adult dataset and chemical synapse are included. Please let us know if/how to make it more useful.
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@zhenlab_Toronto
zhenlab
1 year
At the more depolarized membrane potential range, this neuron initiates reversal; at less depolarized potentials, it sustains forward movement. Locomotion continues during directional transitions.
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@zhenlab_Toronto
zhenlab
1 year
One-sentence summary: spontaneous forward and backward locomotion are not separately controlled by two circuits, but determined by the membrane potential of a narrowly tuned, tonically active premotor interneuron, previously thought to simply activate the reversal circuit.
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@zhenlab_Toronto
zhenlab
1 year
A long journey by @JunMeng_elegans, @_mlechha and Wesley; a pleasure with the Shangbang and Thomas' groups; gratitude to the helpful inputs and warm support from Quan and Aravi  
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@zhenlab_Toronto
zhenlab
1 year
Asymmetry in motor output - forward over reversal; A reversed asymmetry in the property of underlying circuit - neurons of the reversal circuit have higher activity. This study reveals and solves this puzzle.
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@zhenlab_Toronto
zhenlab
2 years
Generating a complete multimodal cell census and atlas of the mouse brain through collaborative data collection, tool development and analysis.
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@zhenlab_Toronto
zhenlab
2 years
RT @Adam_D_Norris: We made a fun tool for visualizing gene expression in the C. elegans nervous system. You can visually explore expressio….
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@zhenlab_Toronto
zhenlab
2 years
RT @NobelPrize: “Ten years ago I was kicked out and forced to retire.”. Our new medicine laureate Katalin Karikó (@kkariko) told us how mu….
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@zhenlab_Toronto
zhenlab
2 years
RT @CIFAR_News: Are you an early-career researcher with ideas that will change the world? 🌏. The CIFAR Azrieli #GlobalScholars program is n….
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@zhenlab_Toronto
zhenlab
2 years
RT @RockefellerUniv: Lily Jan of @UCSF and Eve Marder (@MarderLab) of @BrandeisU have been selected as this year's recipients of the Pearl….
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@zhenlab_Toronto
zhenlab
2 years
We Ask the Canadian Government to Increase CIHR’s Budget - Sign the Petition! via @CdnChange.
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@zhenlab_Toronto
zhenlab
2 years
Congratulations to our institute's new director!.
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@zhenlab_Toronto
zhenlab
2 years
RT @OpenWorm: A major obstacle to modeling the nervous system of the worm has been the unknown weights of the connections. Which are excit….
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@zhenlab_Toronto
zhenlab
2 years
RT @CellRepMethods: Preserving extracellular space for high-quality optical and ultrastructural studies of whole mammalian brains https://t….
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@zhenlab_Toronto
zhenlab
2 years
RT @gsxej: Next up, Philipp's 4K high resolution rendering of all ~127,000 neurons in the FlyWire #drosophila #connectome divided into 9 su….
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@zhenlab_Toronto
zhenlab
2 years
RT @YaronMeirovitch: The octopus brain, diverged from human ancestors 500M years ago, rivals dogs & cats in neuron count! Its memory circui….
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@zhenlab_Toronto
zhenlab
2 years
RT @YaronMeirovitch: We mapped the connections between high order sensory inputs and memory cells in the octopus brain, first-ever reconst….
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@zhenlab_Toronto
zhenlab
2 years
It is worth watching the full recording: who raised the issue, how the exchange went, and how the session ended. It is only a reminder on why everyone has to do something about it.
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@zhenlab_Toronto
zhenlab
2 years
RT @ceri_weber: Here’s a clip of the woman who confronted the panel. I deeply admire her courage. “It is nothing compared to the systemati….
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@zhenlab_Toronto
zhenlab
2 years
RT @gsxej: Working with n>1 connectomes, led us to a new #celltype definition: “a group of cells that are more similar to cells in a differ….
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