Yale MB&B
@YaleMBB
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Yale Molecular Biophysics and Biochemistry (not @YaleMBasketball)
New Haven, CT
Joined September 2018
🧠Pain sensors need to switch on fast—and off just as quickly. In our new tour de force Nature Communications paper, we show that calmodulin plays a key role in shutting down the TRPA1 pain receptor - a finding that could guide new pain therapies. 📰 https://t.co/FjyCcElYoy
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Thank you to everyone who attended this year’s retreat at the Heritage Hotel. A special thank you to retreat coordinators Enrique De La Cruz, Rachel Agosto, and Liz Vellali!
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Malvankar lab publishes pioneer research delving into the quantum mechanics underlying bacterial respiration https://t.co/hKQDkJg3at
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Now online! Conversion of IscB and Cas9 into RNA-guided RNA editors
cell.com
An engineered RNA-guided editing platform for efficient gene knockdown and sequence correction at the mRNA level.
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Congratulations to Enrique M. De La Cruz for his election as President of the Biophysics Society! https://t.co/DaTKzFjH6H
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Happy to see this excellent @laemmerdingLab discussion on our @schliekerlab and Mike's @hennelab recent work connecting organelles to intracellular forces!
.@JulieHeffler and @LammerdingLab @CornellBME discuss recent studies from the @Schliekerlab ( https://t.co/NsL1R6mmbi) and @hennelab ( https://t.co/ys2RkGjuqD) that identify two proteins serving as crucial mechanical elements in the endoplasmic reticulum. https://t.co/lQbF4n4E0V
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We’ve pioneered a disease-agnostic screening platform for aberrant biomolecular condensates—cellular structures linked to incurable neurological diseases. We screened genes and FDA-approved drugs that modulate disease-relevant nuclear condensates: https://t.co/FKchDI7LHB
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Join us next week for MB&B's Computational Biophysics & Biochemistry Symposium on 6/17 in Bass 305.
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Join us in congratulating Tom Pollard on receiving the 2025 Connecticut Medal of Science! Tom and his wife Patty stopped by campus while in town for the award ceremony. 📸 : Joe Wolenski
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Julien Berro thinks about the force – particularly around the 'cytoskeleton' scaffold inside our cells. The member of the Yale Nanobiology Institute spoke w/ @CytoskelJournal about the exciting projects that could pave the way to new medical therapeutics: https://t.co/Lww64BCZl9
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we are beyond proud that our @YaleMBB @schliekerlab undergraduate researcher Sophia graduated as the sole @Yale Colleague '25 graduate with an exceptional distinction in the major! Congrats Sophia for this richly deserved honor!
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#Congratulations to YSM's Gary Brudvig, PhD, Jonathan Ellman, PhD, and Mark Hochstrasser, PhD, who are among five @Yale professors newly #elected to @theNASciences: https://t.co/cL1V33hzSd
@ellman_jonathan @YaleMBB @YalePharm
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#Congratulations to Gary Brudvig, PhD, of @YaleMBB and Valentina Greco, PhD, of @YaleGenetics, who are among eight @Yale #faculty newly #elected to the American Academy of Arts & Sciences. @valentatormenta
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Today in @PNASNews we report the first structure of an antisperm antibody-antigen complex. The naturally occurring OBF13 antibody inhibits sperm IZUMO1 during fertilization, opening avenues for antibody-based contraceptives! @yonggang_lu & Masa Ikawa.
pnas.org
Sperm IZUMO1 binds to egg JUNO, and this interaction is essential for mammalian fertilization. Isolated from a female mouse immunized with syngenei...
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Check out our paper showcasing the first structure of a fully modified human tRNA bound to amino acyl-tRNA synthetase. https://t.co/0NDysz6hhb
academic.oup.com
Abstract. The average eukaryotic transfer ribonucleic acid (tRNA) contains 13 post-transcriptional modifications; however, their functional impact is large
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We are excited to announce a tenure-track or tenured faculty position in Computational Biophysics and Biochemistry, exploring the intricate molecular and cellular processes and the complex interactions of their macromolecular components! Apply now at https://t.co/4TyLyg44vF
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We're excited to announce a tenure-track or tenured faculty position in Cellular Biophysics and Structural Biology! We are especially excited to hear from candidates who develop in situ approaches in structural cell biology. Join us in MB&B! Apply now at https://t.co/it80VM0UyI
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We're excited to announce a tenure-track or tenured faculty position in Cellular Biophysics and Structural Biology! We are especially excited to hear from candidates who develop in situ approaches in structural cell biology. Join us in MB&B! Apply now at https://t.co/it80VM0UyI
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