Vignesh Packiam, MD
@VigneshPackiam
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Associate Prof @RutgersCancer @rwjurology | Previously at @UIowa_Urology | Alum @MayoClinic @Uro_Onc, @UChicagoUro, @PittMedAlum, @UWBadgers| Views my own
New Jersey
Joined November 2013
Very excited to share this project >2 years in the making! Drug-releasing intravesical floating technology (DRIFT) allowing for synchronous delivery yet sequential exposure Could help existing and novel combination regimens! @BladderCancerUS @SUO_YUO @IBCG_BladderCA
pubmed.ncbi.nlm.nih.gov
The DRIFT enables controlled sequential delivery of Gem/Doce, reliably maintaining docetaxel containment for up to 120 min during gemcitabine pre-treatment. Future in vivo validation will establish...
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Almost every case we find something occult on blue light that is subtle or missed on white Hard to believe that would not have a positive impact on outcomes (especially with NMIBC outcomes broadly improving in trials/centers of excellence) @RutgersCancer @saumyg
We recently got a brand spanking🔎🔎 new @PhotocureASA Blue 💙 light system @CleClinicUro and I am slowly convincing 1 resident at a time the incredible value in #bladdercancer starting w/ @eiftu
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1/4 IMVIGOR011 shows ctDNA is a useful predictive and prognostic tool post cystectomy in muscle invasive bladder cancer #ESMO25 . ctDNA positive patients had DFS and OS benifits with atezolizumab. ctDNA negative patients are at a low risk of relapse/cancer death. @OncoAlert
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How do you tailor NMIBC care to the individual, not just the disease? In Episode 2 of our NMIBC Creator Weekend™ series, @SimaPorten @pjhensley11 and @VigneshPackiam discuss patient-centered approaches in bladder cancer care @Ferring #URO266
https://t.co/yZpMJCneJR
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Incredible accomplishment to complete these studies!!! IMO not worth it for almost all patients to be subject to high grade IO toxicity risk for a 5% 2-year benefit (primarily with recurrence not progression)
ALBAN, POTOMAC & CREST #ESMO25 (atezolizumab/sasalimab/in MIBC) @Annals_Oncology show a lot variability. It no easy to conclude exactly which NMIBC patients benefit from ICI therapy. There is over treatment and it’s not without toxicity @JoshMeeks
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🔥@UrolOncol: November issue! Comparative outcomes of radical nephroureterectomy and kidney-sparing surgery in the treatment of high-grade upper tract urothelial carcinoma Click here to read the #OpenAccess article ▶️ https://t.co/2JSrirqWVR
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Great 🧵 on an important paper and topic. Now that there are multiple options for BGC-U NMIBC, need to find a way to sequence them. Cost will be an important piece of that. Lucky to have @AmandaMyersMD at @UIowa_urology continuing this great work!
⚡️ Cost-effectiveness of treatments for BCG-unresponsive CIS - analysis from our multicenter IBCG team. Five strategies modeled: 🔹Radical cystectomy (RC) 🔹Pembrolizumab 🔹Nadofaragene firadenovec 🔹Nogapendekin (NAI-BCG) 🔹Gemcitabine + Docetaxel ➡️Comprehensive
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Season 3 of BackTable Tumor Board is LIVE! Our 8-episode deep dive into the complete management of Non-Muscle Invasive Bladder Cancer. This season is your guide to the latest strategies, from diagnosis to advanced therapeutics. Across the season we cover the entire spectrum of
youtube.com
Check out this 8-episode deep dive into the complete management of Non-Muscle Invasive Bladder Cancer. This season is your guide to the latest strategies, fr...
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⚡️ Cost-effectiveness of treatments for BCG-unresponsive CIS - analysis from our multicenter IBCG team. Five strategies modeled: 🔹Radical cystectomy (RC) 🔹Pembrolizumab 🔹Nadofaragene firadenovec 🔹Nogapendekin (NAI-BCG) 🔹Gemcitabine + Docetaxel ➡️Comprehensive
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It is interesting that re-induction is increasingly acceptable for immunotherapies but not chemotherapy for NMIBC. Some response probably comes from resection and any therapy and I think its hand-waving to say only immunotherapy
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Optimizing patient selection and treatment timing for emerging intravesical therapies. @VigneshPackiam @RutgersCancer joins @zklaassen_md @GACancerCenter to discuss a patient case of a 74-year-old male with multifocal CIS. Dr. Packiam reviews the expanding treatment landscape
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Blue light cystoscopy detects hidden #BladderCancer after induction therapy. @VigneshPackiam @RutgersCancer joins @UroCancerMD @VUMCurology in this discussion of enhanced surveillance protocols for high-risk #NMIBC following induction therapy, presenting findings from nearly 300
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Season 3 of Backtable Tumor Board @_backtableONC covering Non-Muscle Invasive Bladder Cancer has been released with @RutgersCancer @RWJBarnabas Urologic Oncologist Dr. Vignesh Packiam @VigneshPackiam hosting 4 new episodes! ⬇️ Guide to Patient-Centered Counseling in NMIBC Care:
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Optimizing TURBT: Balancing surgical skill and advanced technology. @MarkTysonMD @MayoClinic & @VigneshPackiam @RutgersCancer sit down with @UroDocAsh @MDAndersonNews covering practical considerations including catheter management, environmental sustainability, patient-friendly
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Optimizing patient selection and treatment timing for emerging intravesical therapies. @VigneshPackiam @RutgersCancer joins @zklaassen_md @GACancerCenter to discuss a patient case of a 74-year-old male with multifocal CIS. Dr. Packiam reviews the expanding treatment landscape
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Boarding ✈️ and excited to head to Turin 🇮🇹 ERAS® World Congress (Sept 17–19, 2025) to speak on “Implementation & Administration Challenges in ERAS.” Connecting global leaders in perioperative care 🌍✨ #ERAS2025 @siadaneshmand @saumyg @VigneshPackiam
erassociety.org
The 11th ERAS World Congress was held from September 17th- 19th 2025 in the Lingotto Conference Centre, Turin. This iconic building once housed the Fiat car factory and is famous for the old roof-top...
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How fast do #rcc tumor thrombi grow? 📈 In our cohort @MayoUrology (n=141), venous tumor thrombi expanded ~1 cm/month (wide range). Faster growth seen with higher Mayo level, sarcomatoid/rhabdoid features & metastasis. These data can guide pre-op imaging & surgical triage.
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Organoids are not science fiction. They are mini-organs built from stem cells, mirroring human biology. From cancer care to drug discovery, they bring medicine closer to the patient, not the mouse. @CellPressNews @OncoAlert #Cancer #science
https://t.co/3xMJKKQRqy
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Computational histology AI guides treatment selection for #BladderCancer patients. @VigneshPackiam @RutgersCancer joins @UroCancerMD @VUMCurology discussing this innovative test, which analyzes standard H&E slides from pre-treatment TURBT specimens, examining 600-700 microscopic
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