VanVeller Group
@vanvellergroup
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organic and bioorganic chemistry, peptide chemistry, photochemistry
Joined March 2019
RT @ChemicalScience: Amidines are an isostere of the amide bond but are unexplored in peptide secondary structure. The @vanvellergroup fro….
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Congratulations to our 4th year grad student @emilyob51 for her acceptance into the Iowa State Graduate College Emerging Leaders Academy! 🎉 @ISUGradCollege @IASTATE_Chem
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RT @J_A_C_S: General Installation of (4H)-Imidazolone cis-Amide Bioisosteres Along the Peptide Backbone | Journal of the American Chemical….
pubs.acs.org
Imidazolones represent an important class of heterocycles present in a wide range of pharmaceuticals, metabolites, and bioactive natural products and serve as the active chromophore in green fluore...
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Congrats to Moha, Aaron, Emily, and Brendan on their well-deserved graduate student research awards!
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What can't the thioimidate do? Check out our most article in @JOC_OL on thioimidate solutions to thionopeptide deprotection!.
pubs.acs.org
Thioamides have structural and chemical similarity to peptide bonds, offering valuable insights when probing peptide backbone interactions, but are prone to side reactions during solid-phase peptide...
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A rapid amidine cyclization enables insertion of (4H)-imidazolones––a cis-amide bioisostere––into peptides during SPPS – out now in JACS! 🧪.
pubs.acs.org
Imidazolones represent an important class of heterocycles present in a wide range of pharmaceuticals, metabolites, and bioactive natural products and serve as the active chromophore in green fluore...
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RT @brettvanveller: Our department is hiring an assist/assoc prof in organic chemistry, broadly defined. #chemistry #chem #chemtwitter Plea….
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RT @ampepsoc: SESSION 4: PROTEIN ARCHITECTURES – STRUCTURE AND FUNCTION.L20 – Brett VanVeller, Iowa State University.Thioimidates: An Obscu….
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RT @brettvanveller: Special moment when you get to present in the same section as your former advisor Ronald Raines at APS #peptides2023. W….
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It’s award ceremony season and our lab recently celebrated grad students @brendanxwall and @emilyob51 on their @IASTATE_Chem departmental awards! . Of course they had to get a picture with Rosalind too! 🧬
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RT @ampepsoc: AGENDA HIGHLIGHT Session 4: Protein Architectures: Structure and Function featuring Ronald Raines, Emma Watson @Dr_EmmaWatson….
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RT @ACSSynBio: "The synthetic strategy developed in this study represents the first robust and general procedure for the introduction of am….
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RT @J_A_C_S: A General Strategy to Install Amidine Functional Groups Along the Peptide Backbone @brettvanveller @IowaStateU #Modification #….
pubs.acs.org
Amidines are a structural surrogate for peptide bonds, yet have received considerably little attention in peptides due to limitations in existing methods to access them. The synthetic strategy...
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RT @ACSPublications: Check out this ACS As Soon As Publishable (ASAP) article from @J_A_C_S: A General Strategy to Install Amidine Function….
pubs.acs.org
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Taking amidines where no amidine has gone before…linear peptides during SPPS! 🚀 @IASTATE_Chem
pubs.acs.org
Amidines are a structural surrogate for peptide bonds, yet have received considerably little attention in peptides due to limitations in existing methods to access them. The synthetic strategy...
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