Tomas Fitzgerald
@tomaswfitz
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Joined March 2013
RT @OpenTargets: NEW: Postdoctoral Fellow with @ewanbirney. The project is based in the Birney Research group at @emblebi and working close….
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RT @ewanbirney: Got a PhD in bioinformatics or quantiative/CS degree? Want to work with AI on real world health care data, using some of th….
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RT @saulpierotti: New preprint 📣. In this work with @IanBrettell we developed a behavioural assay for medaka fish and the associated downst….
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RT @MariosGeorgakis: 📢Our preprint on deep learning for carotid plaque detection in 170,000 UK Biobank ultrasound images is out❗️. 👉robust….
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RT @emblebi: Genome-wide association studies focusing on SNPs have advanced our understanding of certain diseases but are reaching limits f….
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RT @GWASCatalog: Looking to the future, we ask what kind of genetic variation will be a priority for genome wide studies in the coming year….
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This was a really fun review to write together, interesting to reflect on why it’s taken so long for CNVs to level up to similar large scale GWAS applications - lots still to do but slowly getting closer to the SNP GWAS world 😀.
Genome-wide association testing beyond SNPs #Review by Laura Harris, Ellen McDonagh, @xiaolei_gene, Katherine Fawcett, @AmzForeman, Petr Daneck, Panagiotis Sergouniotis, @DrP_stuff, @franz_mazz, @minouye271, @edhollox, @ewanbirney & @tomaswfitz @emblebi.
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RT @ewanbirney: Got a PhD in a quantitative science? Want to work on AI and healthcare data? Want to work with one of the most innovative P….
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RT @saulpierotti: We have a new preprint out 🥳. FlexLMM is a Nextflow pipeline for running linear mixed models for GWAS that focuses on fle….
arxiv.org
Summary: Linear mixed models are a commonly used statistical approach in genome-wide association studies when population structure is present. However, naive permutations to empirically estimate...
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RT @saulpierotti: Excited to share that my first first-author paper is online on @BioinfoAdv ! Check it out and thanks to amazing collabora….
academic.oup.com
AbstractMotivation. Crosses among inbred lines are a fundamental tool for the discovery of genetic loci associated with phenotypes of interest. In organism
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RT @artem_shmatko: How much does your medical history reveal about your future?. As a team effort of @MoritzGerstung and @ewanbirney's labs….
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RT @EllieMcDonagh: Are you interested in how our genetic variation affects our response to medication? Apply for a Bridging Excellence #Fel….
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RT @ewanbirney: A new preprint - and first from my lab from @saulpierotti - on a technical subject which we were frustrated by the lack of….
biorxiv.org
Motivation Crosses among inbred lines are a fundamental tool for the discovery of genetic loci associated with phenotypes of interest. In organisms for which large reference panels or SNP chips are...
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RT @doctorveera: In 2010, the first genome-wide significant locus for frontotemporal lobar degeneration (FTLD) was discovered--an LD block….
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RT @EBItraining: 🐟We have a few last-minute places on offer for our free, virtual #medaka #fishmodels workshop next week!. 🔗Secure your pla….
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RT @EBItraining: Are you a scientific researcher with experience in using #fishmodels for #genetic & #phenotypic analysis with an interest….
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RT @embl: Copy number variation (CNV) in the genome can lead to complex human diseases, including neurological disorders. CNest is a new,….
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RT @ewanbirney: 🎺New paper published🎺.CNest, the shiny new, "do real proper /common/ CNV association studies" off Whole Exome or Whole Geno….
cell.com
CNest copy number variation (CNV) genome-wide association study (GWAS) testing brings CNVs into a similar framework as those widely used in SNP GWAS. We made over 800 new discoveries in the UK...
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RT @smshuai: Happy to announce that I have started my own group @SUSTechSZ. Super grateful to all the great mentors I have been working wit….
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Really welcome any comments and suggestions (also critique) from anyone who finds this approach interesting.
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