Today is our birthday!! 🎂#15yearsGWASCatalog🎂 We are the result of all #gwas community and the effort of current and past team members, curators, data scientists, developers, managers, team and project leads, @embl @emblebi and @genome_gov !! Thanks all for your contribution 👇

We’re excited to keep developing PEGASUS together - join us and access materials on our GitHub community page ! 👉

A huge thank you to everyone who joined our #ASHG25🧬 ancillary session on the PEGASUS framework! We were delighted to see the engagement & discussion around Predicted Effector Genes (PEG) and our new framework⊞ - for representing gene prioritisation evidence🔍 & conclusion📌.

We recently passed 1 million curated SNP-trait associations! See how the GWAS Diagram has changed with the significant data growth. Contribute to our growing dataset and the diagram view by submitting your #SumStats and now also your top assoc. https://t.co/1wHeyIeASk

What is the GWAS Catalog diagram? 🧬 Cytoband-trait association plot, now with: ✨ Non-overlapping in crowded regions ✨ Fully interactive (p ≤ 5e-8) ✨ Links to study, SNP & trait pages ✨ Filter by parent trait

🚨 NEWS! The GWAS Catalog Diagram is back up! 🚨 Smoother, faster loading for filtered views! 🗺️Explore now 👉 https://t.co/GTO3xyc3Z1 Tell us what you think! Are there any features you would like? Help us to make it useful for the #gwas community

Want to recieve updates like this directly to your inbox? Sign up for our low-volume mailing list by sending an e-mail to gwas-announce-join@ebi.ac.uk with subject heading "subscribe" ✅

The split file facilitates analysis for users of Excel or other software which cannot handle >1m rows. Please note that data may continue to be added for previous years - you are advised to always work with the latest version of the complete file set. 👇

1. File now provided as a compressed .zip; data format unchanged. 2. Data split into multiple smaller files, and compressed together. The split file (2) is divided by publication year, with a separate file for each year from 2023 onwards, and pre-2023 data in a single file. 👇

🚨 Using the GWAS Catalog “All associations” tsv download? We recently made some changes that may affect your pipelines. Data now includes >1m top associations! This means the “All associations” file is very large. In the latest release, you now have a choice of 2 formats 👇

Meet PEGASUS! Working on post-GWAS analyses to predict effector genes at GWAS loci? Come to room 259A 11:45 TODAY to find out more #ASHG25

At #ASHG25 and want to meet members of the GWAS Catalog & @PGSCatalog teams? Stop by the @impc booth 1420 where we're helping out!

🚨 Countdown to #ASHG25: Predicted Effector Gene standard is coming! 🚨 Join us and be part of the conversation! 📌 Poster Oct 16 | 2:30–4:30 | Poster Hall 🗓️ Session Oct 17 | 11:45–1:15 | Room 259A Learn more:

🧩 Toward a standard for Predicted Effector Genes → From PEG list to PEG matrix Join us at #ASHG2025 to know about the work done and future directions WG materials: https://t.co/W9hOZyvhT7 Learn more: https://t.co/WighBoJRZd #ASHG25 #EffectorGene #PEGstandard #AncillarySession

GWAS finds millions of variants — what are the Predicted Effector Genes (PEGs)? Our Nature Genetics Perspective https://t.co/hDY8btkjHv showed big inconsistencies. At ASHG 2025, we’ll introduce a new standard to make PEG data FAIR 🗓️ Ancillary Session: Oct 17 | 11:45 | Room 259A

🌏 Shaping Together 🌏 Last year, we hosted a workshop on Predicted Effector Gene (PEG) lists - key data linking GWAS to biology 👉 https://t.co/W9hOZyuK3z At #ASHG25, we share a proposed PEG standard 🗓️ Ancillary Session: Oct 17 | 11.45AM 📌Poster: Oct 16 | 2:30PM | Poster Hall

🚩1 MILLION curated associations!!! 🚩 Launched in 2008, took us 15 years to reach 500K, and thanks to your research and collaboration, we doubled the number in less than 3 years! See some data insights https://t.co/1sok6ghprr #OpenAccess

🚨NEWS!! OUR REST API V2 IS OUT!!! 🚨 ✅Find more data available thanks to new endpoints ✅New search and filtering functionalities ✅Integration with resources like Ensembl REST API v1 available until May ’26 More details https://t.co/zOoO6MV8Vu

🧬 Whether you build or use PEG lists, this is your moment to lead. Let’s make PEG data truly work for the community! #ASHG #EffectorGene #GenePrioritisation #FunctionalGenomics #datastandard #OpenAccess

What you'll get: ✅ Reusable PEG matrix framework pointing to key genes ✅ Real examples of enhanced PEG knowledge sharing ✅ Practical framework for #FAIR genomics data ✅ Your voice in shaping the standard!

🚨 Join us at #ASHG25! We’re unveiling a new standard for Predicted Effector Gene (PEG) data - designed to make gene prioritisation more transparent, reusable, and #FAIR. #HumanGenetics #GeneticsDiscoveries #EffectorGene #GWAS #FunctionalGenomics #PEGstandard👇