Thiogenesis Therapeutics
@thiogenesis
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Developing thiol compounds that are strong antioxidants for inherited mitochondrial diseases & related metabolic conditions like fatty liver disease etc. $TTI.v
Joined July 2022
Good post - lets add inherited mitochondrial disease and fatty liver disease to the list. $TTI.v $TTIPF #MELAS #Leighs #pedMASH #oxidativestress
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It seems likely that mitochondria transfer and mitochondria-based therapies will be a significant part of medicine in the future.
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Excited to be on my way to talk mitochondria with @hubermanlab
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Taurine improves literally every metric of insulin resistance. New review, finding taurine supplementation: ↓ Fasting blood glucose: −5.90 mg/dL ↓ HbA1c: −0.21% ↓ Fasting insulin: ~10-20% ↓ HOMA-IR: −0.57 ↓ Triglycerides: −14.42 mg/dL ↓ Total cholesterol: −12.41
TAURINE: An anti-aging, anti-inflammatory, stress reducing and brain protective nutrient. Let's talk about its numerous benefits, the science behind it, and how you can incorporate it to maximize your health:
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Inflammation is behind nearly every chronic disease— From stubborn belly fat to heart attacks. But no one talks about how to actually fix it. Here are 10 underrated anti-inflammatory cheat codes your doctor won't mention:🧵
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TTI-0102 is a precursor to hypotaurine which is oxidized into Taurine -- excellent summary below $TTI.v $TTIPF #taurine #mitochondria #MELAS #Leighsyndrome
Taurine is a sulfur-containing amino acid known for its critical involvement in skeletal muscle, heart and brain function. With high concentrations found in excitable tissues such as muscle, brain, and heart, taurine is essential for maintaining cellular homeostasis. It
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The beauty of taurine beyond everything mentioned here is the fact that it has a sparing effect on nutrients tied to methylation (especially when saturated with all methylation nutrients) due to cysteine's metabolism down the transsulfuration pathway. This means higher doses of
Taurine appreciation post. - It spares magnesium. - Improves glutamate/GABA balance, shifting neurochemistry towards inhibitory tone - unlocking a calm/zen state. - Huge benefits in mitochondrial function + redox. - Supports bile flow (fat-soluble vitamins, fatty acids,
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Nice post about mitochondrial health - well worth a read.
Your mitochondria predict your death date. 10,000+ studies confirm that dysfunction triggers cancer, heart failure, and 300+ other diseases. Here’s the protocol to restore your mitochondria at any age (based on science):🧵
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Eager to add a Phase 3 orphan program to the company's pipeline. $TTI.v $TTIPF #cystinosis #lysosome #orphandrug
newsfilecorp.com
San Diego, California--(Newsfile Corp. - November 24, 2025) - Thiogenesis Therapeutics, Corp. (TSXV: TTI) (OTCQX: TTIPF) ("Thiogenesis" or the "Company"),...
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Exciting news - interim phase 2 MELAS data, update on Leigh syndrome $ the introduction of a new late stage clinical program in cystinosis! $TTI.v $TTIPF #MELAS #cystionsis
newsfilecorp.com
San Diego, California--(Newsfile Corp. - November 4, 2025) - Thiogenesis Therapeutics, Corp. (TSXV: TTI) (OTCQX: TTIPF) ("Thiogenesis" or the "Company")...
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The FDA has accepted Stealth BioTherapeutics’ third new drug application for its ultrarare disease candidate, providing a planned decision date of Sept. 26.
fiercebiotech.com
The FDA has accepted Stealth BioTherapeutics’ new drug application for its ultrarare disease candidate, providing a
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The ORPHAN Cures Act will enable more options for Americans living with rare disease. Congress must pass the #ORPHANCuresAct to ensure continued investment in lifesaving treatments and to protect U.S. #biotech leadership.
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Looking forward to filing IMPD for a Ph 2a pediatric MASH trial in the EU - an unserved market for kids with severe liver disease. $TTIV $TTIPF #mito #fattyliver #oxidativestress
https://t.co/vS6WkRGh6M
newsfilecorp.com
San Diego, California--(Newsfile Corp. - June 25, 2025) - Thiogenesis Therapeutics, Inc. (TSXV: TTI) (OTCQX: TTIPF), a clinical-stage biopharmaceutical company...
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Looking forward to a good turnout at MitoMed 2025. $TTI.v $TTIPF #mito #Leigh's #melas
https://t.co/9TG96NOdpg
newsfilecorp.com
San Diego, California--(Newsfile Corp. - June 20, 2025) - Thiogenesis Therapeutics, Corp. (TSXV: TTI) (OTCQX: TTIPF) ("Thiogenesis" or the "Company"),...
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Thiogenesis is excited to start dosing MELAS patients in France, looking forward to interim data in September. $TTI.v $TTIPF #mito #MELAS #Angers
https://t.co/OxyFDqo0Hz
newsfilecorp.com
San Diego, California--(Newsfile Corp. - June 17, 2025) - Thiogenesis Therapeutics, Corp. (TSXV: TTI) (OTCQX: TTIPF) ("Thiogenesis" or the "Company")...
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Great news today - excited to clear IND for LSS. $TTI.v $TTIPF #mitochondria #Leighsyndrome #cysteine #glutathione #IND
newsfilecorp.com
San Diego, California--(Newsfile Corp. - June 11, 2025) - Thiogenesis Therapeutics, Corp. (TSXV: TTI) (OTCQX: TTIPF) ('Thiogenesis' or the 'Company')...
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Health and Human Services Secretary Robert F. Kennedy Jr. said on Thursday that the U.S. drugs regulator would look for ways to fast-track approval for rare disease treatments and remove obstacles to their path to market.
reuters.com
Health and Human Services Secretary Robert F. Kennedy Jr. said on Thursday that the U.S. drugs regulator would look for ways to fast-track approval for rare disease treatments and remove obstacles to...
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With over 95% of rare diseases lacking approved therapies, the ORPHAN Cures Act would be a game-changer for the rare disease community. RDCC thanks @SenJohnBarrasso and @SenatorHeinrich for their leadership, and we will continue our work to advance this important policy.
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