Adam Hall
@the_adam_hall
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Associate professor @wakehealth in @wakebme studying nanopores and micro tissues. I am large, I contain multitudes. He/him.
Winston-Salem, NC
Joined November 2015
Our newest paper is out now in @ACS_Sensors: improving the selective solid-state #nanopore assay with a His-tagged monovalent streptavidin. The new reagent took a lot of work, but we have it now so reach out if you need some!.
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Our latest paper collab with lots of great colleagues is now available in @an_chem, extending our solid-state #nanopore approach to analyzing the size distribution of heavy-chain modified #hyaluronan from physiological biofluids.
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Have we settled on an alternative platform for the #nanopore community yet? I can't with all of this. Threads? Insta? Tell me and I'll meet you all there.
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RT @WanunuLab: Nanopores are an enticing system for achieving de novo protein sequencing but there are hurdles to overcome, even before app….
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Congrats to my @BEAMvt colleague Scott Verbridge (on the VT side of the department) and all authors on a really exciting cover article in @scisignal!
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Strong contender for most under-utilized institute in America
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Follow up: they just added an underscore at the end of my real twitter handle. I didn’t join in 2022, either.
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I’m told by @Oukhaled that someone is posing as me on twitter with a legitimate photo and contacting colleagues. Please note that I rarely send messages on here and never ask for anything beyond an occasional RT. Thank you, Ghani and I hope nobody is taken advantage of.
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Congratulations to Felipe on successfully defending his dissertation today! A great presentation on a lot of great work!
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NEW POSTDOC POSITION: We are looking to hire a new postdoc to contribute to our lab's translational solid-state #nanopore research! Work will focus on nucleic acid #biomarkers including base lesions and microRNA in clinical samples. RTs appreciated!
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European #nanopore folks: a colleague in glycosciences in Copenhagen, Dr. Rebecca Miller, is offering a PhD fellowship focused on utilizing nanopores to examine sulfated GAGs. If you know of someone, please pass on the link. cc @TheNanoporeSite
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This is, by the way, for a special issue celebrating the eighth Nano Research Award to @cees_dekker. Congrats, Cees!.
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In this way, he was able to improve our measurement sensitivity by two orders of magnitude to 100 pM while keeping selectivity high.
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The major outcome of this paper is that the use of asymmetric salt (lower concentration on the side with molecules) can be used to increase the complex rate while keeping constituent rates low.
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Changing salt conditions can increase our sensitivity (how little material is needed for detection), but that can also reduce selectivity by making the constituents visible, too.
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