Tannin Schmidt
@tanninschmidt
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Biomedical Engineer (UConn Health) & Entrepreneur (Lubris) ... all things PRG4/lubricin, Dad, Husband, and lover of ketchup chips. Tweets are my own.
Farmington, CT, USA
Joined March 2015
New PRG4 paper on aging! The molecule that never ceases to surprise: Serum PRG4 down with age. Deficiency results in decreased survival in mice and accelerated skeletal aging in M mice. Great work by former PhD student @ATang029 and awesome collaborators.
pubmed.ncbi.nlm.nih.gov
Proteoglycan 4 (PRG4) is a mucin-like glycoprotein best known as a boundary lubricant of articular cartilage; however, it also has anti-inflammatory, anti-fibrotic, and immunomodulatory properties....
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RT @Nature: A US judge has blocked a policy that would have, beginning today, slashed billions of dollars of funding annually for US resear….
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RT @nguyenuconn: Our lab ( at UConn have now several available positions for Postdocs in vaccine delivery, micronee….
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RT @BajpayeeLab: Less than two weeks to the 2024 SFB Northeast Symposia at Northeastern University. Don't forget to register!.
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RT @jflier: What if I told you that I co-founded a startup in 1987 that obtained world-wide rights to GLP1 as a metabolic Rx, collaborated….
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RT @thechowlab: So excited for this amazing lineup of speakers for the @SFBiomaterials Northeast Regional Symposium @Northeastern! 🤩 Today….
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RT @NBCOlympics: Andre de Grasse anchors Canada to 4x100m GOLD in Paris! 🇨🇦 #ParisOlympics . 📺 NBC & Peacock
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RT @COREeyenews: Huge congratulations to CORE director @lwj_63 for being recognized by the American Academy Of Optometry with the Carel C.….
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Excited to share @LubrisBio’s full length recombinant human #PRG4 (#rhPRG4) / #lubricin drug product is released for an upcoming #dryeye clinical study in Australia. Packing and labelling is complete, and we’re ready for distribution upon ethics committee approval. Stay tuned!
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Proud of the #PRG4 #lubricin manufacturing progress made working with @LubrisBio & @AvidBioservices the past 2+ years = a 500L GMP run. Eye drop bottles now filled as we push towards the clinic and 2 GRAMS (!) of #rhPRG4 leftover for future preclinical research the next 5+ years.
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I'm hiring! BME PhD position available in Fall of 2024 at UConn Health. Must be a US citizen or permanent resident. See below and please inquire with any questions or interests!
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Excited to share a new collaborative study lead by Ali Tamayol’s @limb_lab in Advance Healthcare Materials: microneedles with dissolvable backing for the programmed delivery of #PRG4/#lubricin to treat wounds. #uconn #uconnhealth.
advanced.onlinelibrary.wiley.com
Skin wound healing is a complex process in which macrophages play a central role. In this study, the application of recombinant human Proteoglycan-4 (rhPRG4) in the immunomodulation of the skin...
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RT @COREeyenews: 🚨🚨🚨Milestone Alert🚨🚨🚨.Did you know that Lyndon Jones reached a major milestone at the recent #NCC2024 conference in the Ne….
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RT @ParrenoJustin: @ManzoniThomas and Elizabeth Davis’ (Kandel lab) new paper with @tanninschmidt and others not on x: passaged superfici….
journals.sagepub.com
Background: Bioengineered cartilage is a developing therapeutic to repair cartilage defects. The matrix must be rich in collagen type II and aggrecan and mechan...
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RT @BrianneConnizzo: Thanks for coming out to Honest @AlanGrodzinsky's Continuum Dinner. We missed our fearless leader this year, but I thi….
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#PRG4 #lubricin AlphaLISA from @RevvityLifeSci! We developed it with @LubrisBio #rhPRG4, showed PRG4 down in Sjogrens tears, now great to have a kit made/optimized by Revvity CustomTeams. LLOQ ~5ng/ml, only 5ul of sample. Great for serum, tears, saliva - and we’ll see what else!
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