
Ryota Takaki
@takaki_ryota
Followers
122
Following
183
Media
5
Statuses
50
Biological soft matter physics, Posdoc @ Max-Planck-institute, Dresden. Condensates, molecular motors, and Non-equilibrium stuff in general.
Dresden, Sachsen
Joined November 2017
Some important findings.1. DNA loop fix the position of DNA-protein condensate. 2. DNA loop stabilize the condensate formation for high tension on DNA. 3. DNA loop with condensation creates longer range interactions of DNA segments, resulting in TAD like structure. @brugueslab.
0
0
1
This work was started when I was in Austin. Big thanks to my PhD advisor and coauthor @davethirum @ThirumalaiArmy.
0
0
1
Very excited to share the preprint on the computational study of protein aggregates :) .We questioned the various morphologies and dynamics of protein aggregates found in experiments. Our study shows the entropy of the sequence and rigidity matters! .
biorxiv.org
Understanding the biophysical basis of protein aggregation is important in biology because of the potential link to several misfolding diseases. Although experiments have shown that protein aggrega...
2
2
15
Cannot find some articles from PRXLife in google scholar including ours. Should we just be patient ? @PRX_Life.
1
0
3
This is work with @mpopov1c @LJawerth and Frank Jülicher published in @PRX_Life. @marionamec made a beautiful video (my voiceš) to explain aging phenomenon in protein condensates. We tried to explain the bewildering concept plainly in the video.
1
2
10
RT @PRX_Life: #ProteinCondensates play a key role in cellular functions. A recent experiment showed their viscosity changes with time. So aā¦.
0
7
0
RT @tienhung_91: Looking to fill 1 or 2 postdocs who are interested in developing computational models to investigate structures & dynamicsā¦.
0
9
0
Our preprint āTheory of rheology and aging of protein condensatesā appeared in arXiv :D This is work with @mpopov1c, @LJawerth and Frank Jülicher. We develop a theory to understand Maxwell glass behavior for condensates rheology. Please check it out !
arxiv.org
Biological condensates are assemblies of proteins and nucleic acids that form membraneless compartments in cells and play essential roles in cellular functions. In many cases they exhibit the...
2
11
39
Any current concerns for Twitter doesnāt negate the joy to get followed by my academic idol 𤯠@gavincrooks.
1
0
6
Finally I can share the published version of our paper ! We find universal mechanism among dimeric molecular motors using information theory and stochastic thermodynamics. Please check it out !. @davethirum @ThirumalaiArmy.
pnas.org
Molecular motors, kinesin and myosin, are dimeric consisting of two linked identical monomeric globular proteins. Fueled by the free energy generat...
2
3
24
Happy to find out the important debate about kinesin stepping was solved, and cited by a Nobel laureate !.
pnas.org
Conventional kinesin, responsible for directional transport of cellular vesicles, takes multiple nearly uniform 8.2-nm steps by consuming one ATP m...
#MINFLUX now changes the game of protein tracking:.š¶šš¶..MINFLUX dissects the unimpeded walking of kinesin-1. See also spectacular work by @JonasRies lab in living cell:.
0
0
5
Lmao.āhe wanted to learn to cook. As a total beginner, he adopted the strategy of making the same dish ā a simple pasta in oil ā every day until it was perfect. For six months, thatās exactly what he did.(To date, according to Kim, thatās the only dish he knows how to cook.)ā.
0
0
0