Ryota Takaki Profile
Ryota Takaki

@takaki_ryota

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122
Following
183
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50

Biological soft matter physics, Posdoc @ Max-Planck-institute, Dresden. Condensates, molecular motors, and Non-equilibrium stuff in general.

Dresden, Sachsen
Joined November 2017
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@takaki_ryota
Ryota Takaki
1 year
Some important findings.1. DNA loop fix the position of DNA-protein condensate. 2. DNA loop stabilize the condensate formation for high tension on DNA. 3. DNA loop with condensation creates longer range interactions of DNA segments, resulting in TAD like structure. @brugueslab.
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@takaki_ryota
Ryota Takaki
1 year
Happy to share a new preprint !😃.This work is with Yahor Savich, Jan brugués, and Frank Jülicher. Loop extrusion and protein condensates are two important aspects of chromatin organization. Have you wondered what if they coexist ? Here is an answer: .
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@takaki_ryota
Ryota Takaki
1 year
This work was started when I was in Austin. Big thanks to my PhD advisor and coauthor @davethirum @ThirumalaiArmy.
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@takaki_ryota
Ryota Takaki
1 year
Very excited to share the preprint on the computational study of protein aggregates :) .We questioned the various morphologies and dynamics of protein aggregates found in experiments. Our study shows the entropy of the sequence and rigidity matters! .
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biorxiv.org
Understanding the biophysical basis of protein aggregation is important in biology because of the potential link to several misfolding diseases. Although experiments have shown that protein aggrega...
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@takaki_ryota
Ryota Takaki
1 year
Cannot find some articles from PRXLife in google scholar including ours. Should we just be patient ? @PRX_Life.
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@takaki_ryota
Ryota Takaki
2 years
I’m very happy to be awarded a poster prize with a gift card for the recent work on the protein condensates, which will be converted to protein powder shortly 😃.
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@takaki_ryota
Ryota Takaki
2 years
This is work with @mpopov1c @LJawerth and Frank Jülicher published in @PRX_Life. @marionamec made a beautiful video (my voicešŸ™ˆ) to explain aging phenomenon in protein condensates. We tried to explain the bewildering concept plainly in the video.
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@takaki_ryota
Ryota Takaki
2 years
I’m very happy to share the published version of our paper ! :D This is a theoretical investigation on the Maxwell glass rheology observed in biological condensates. I have worked on Maxwell demon in molecular motors and now Maxwell glass in condensates :D
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@takaki_ryota
Ryota Takaki
2 years
RT @PRX_Life: #ProteinCondensates play a key role in cellular functions. A recent experiment showed their viscosity changes with time. So a….
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@takaki_ryota
Ryota Takaki
2 years
RT @tienhung_91: Looking to fill 1 or 2 postdocs who are interested in developing computational models to investigate structures & dynamics….
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@takaki_ryota
Ryota Takaki
2 years
Had a brief conversation with the boss of the institution. He didn’t know today is a holiday.
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@takaki_ryota
Ryota Takaki
2 years
RT @at_ray_o: Our paper on #3dgenome structure at #mitosis is finally out in cell reports. We develop a theory that shows; how many #conden….
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@takaki_ryota
Ryota Takaki
2 years
Our preprint ā€œTheory of rheology and aging of protein condensatesā€ appeared in arXiv :D This is work with @mpopov1c, @LJawerth and Frank Jülicher. We develop a theory to understand Maxwell glass behavior for condensates rheology. Please check it out !
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arxiv.org
Biological condensates are assemblies of proteins and nucleic acids that form membraneless compartments in cells and play essential roles in cellular functions. In many cases they exhibit the...
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@takaki_ryota
Ryota Takaki
2 years
I have a presentation today titled as ā€œTheory and rheology of aging protein condensatesā€, in the session M06. Time is 9:36-9:48. Please come and check it out if you are interested in rheology of Biomolecular condensates and its Glassy behavior ! . #APS2023 #APS.
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@takaki_ryota
Ryota Takaki
3 years
Arrived MBSJ 2022 :) It is actually my FIRST CONFERENCE in Japan ! Very exited !
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@takaki_ryota
Ryota Takaki
3 years
Any current concerns for Twitter doesn’t negate the joy to get followed by my academic idol 🤯 @gavincrooks.
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@takaki_ryota
Ryota Takaki
3 years
Finally I can share the published version of our paper ! We find universal mechanism among dimeric molecular motors using information theory and stochastic thermodynamics. Please check it out !. @davethirum @ThirumalaiArmy.
pnas.org
Molecular motors, kinesin and myosin, are dimeric consisting of two linked identical monomeric globular proteins. Fueled by the free energy generat...
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@takaki_ryota
Ryota Takaki
3 years
I will be having a invited talk at MBSJ 2022 in Japan. Just found out there is official theme song for the conference, ā€œassistant professor’s counter attackā€. šŸ˜‚ .
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@takaki_ryota
Ryota Takaki
3 years
Happy to find out the important debate about kinesin stepping was solved, and cited by a Nobel laureate !.
pnas.org
Conventional kinesin, responsible for directional transport of cellular vesicles, takes multiple nearly uniform 8.2-nm steps by consuming one ATP m...
@Stefan_W_Hell
Stefan W. Hell
3 years
#MINFLUX now changes the game of protein tracking:.šŸŒ¶šŸ˜ŽšŸŒ¶..MINFLUX dissects the unimpeded walking of kinesin-1. See also spectacular work by @JonasRies lab in living cell:.
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@takaki_ryota
Ryota Takaki
3 years
Lmao.ā€œhe wanted to learn to cook. As a total beginner, he adopted the strategy of making the same dish — a simple pasta in oil — every day until it was perfect. For six months, that’s exactly what he did.(To date, according to Kim, that’s the only dish he knows how to cook.)ā€.
@tienhung_91
Hung Nguyen
3 years
Interesting life story! Slow and deep thinker. Oh, and he only works 3h per day.
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