Stella Lima
@stella_lima33
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PhD. Current postdoc in the @ChekanLab @uncg_chem, interested in biosynthesis, enzymes and natural products🧫🧬👩🏽🔬|🐶🧘🏽♀️🏄🏽♀️🤸🏽♀️|🇧🇷she/her
Sao Paulo, Brazil
Joined January 2020
I’m very pleased and stoked to share the main work of my entire PhD and also part of my Master’s! The biosynthesis of one of the most powerful cyanotoxins!! It was an honor to work on such an incredible project with such an amazing team! @BradMoore_SIO @FioreMarli @shaunmckinnie
Thrilled that our first major research paper is published in @J_A_C_S! Such a fun collaboration with @stella_lima33, @MarliFiore, and @BradMoore_SIO to discover and characterize the biosynthetic genes that produce the organophosphate cyanotoxin guanitoxin https://t.co/GNc4rqfHk3
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Congratulations to Draco from our lab for defending his master's thesis! He did a fantastic job and we are impressed with all he accomplished!
Congratulations, Draco Kriger, for successfully defending your master’s thesis! It was a great talk and cool research on RiPPs! Congrats also to @ChekanLab 🥳 @uncg_chem
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Come join our fantastic department!
We are looking for a new Director of our MS facility at the highly collegial @uncg_chem. Our focus is on #metabolomics, small molecule quantitation & #naturalproducts. please rt https://t.co/QCAmIuAuae
#massspectacular
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My first first author paper is published! Thank you to all the wonderful coauthors and I’m excited that I get to help continue the guanitoxin project!
Check out our GntC enzymology story out today in @ACSCatalysis! Happy first first to @jencordoza - so beyond proud of you! And huge thanks to our amazing coauthors (@thePYTC @stella_lima33 @MarliFiore @ChekanLab @BradMoore_SIO and Linnea Blaustein)! https://t.co/mzpb3FSLL9
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Check out our GntC enzymology story out today in @ACSCatalysis! Happy first first to @jencordoza - so beyond proud of you! And huge thanks to our amazing coauthors (@thePYTC @stella_lima33 @MarliFiore @ChekanLab @BradMoore_SIO and Linnea Blaustein)! https://t.co/mzpb3FSLL9
pubs.acs.org
Cyclic arginine noncanonical amino acids (ncAAs) are found in several actinobacterial peptide natural products with therapeutically useful antibacterial properties. The preparation of ncAAs like...
Hey everyone! If you like: - cyclic arginine amino acids - mechanistic enzymology - cyanobacterial biosynthesis - deuterium labeling - PLP cofactors - first first author papers from @jencordoza, or all of the above, then please check out our newest preprint on bioRXiv!
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It’s awesome to see another paper coming out from the guanitoxin biosynthesis! Huge congrats to @shaunmckinnie and @jencordoza 👏🏽👏🏽👏🏽🍾🎆🎇
Hey everyone! If you like: - cyclic arginine amino acids - mechanistic enzymology - cyanobacterial biosynthesis - deuterium labeling - PLP cofactors - first first author papers from @jencordoza, or all of the above, then please check out our newest preprint on bioRXiv!
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Haven't seen a better representation of what a Ph.D. is/should be. #AcademicTwitter #academia #research @PhDVoice @PhD_Genie
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Plants 🌱 are an incredible universe to explore natural products 🪴🌿 Stoked to be part of this project
Beyond excited for our first paper to be published! Congrats to @stella_lima33 @EthanU99 @mikepasquale77 Brigitte, Imani, Tyler, and Cody!
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As part of the 40th anniversary of @TrendsinBiotech, we spotlight an achievement in NP production. In 2013, Paddon et al reported 25g/L fermentation of artemisinic acid coupled with synthetic steps to yield the essential antimalarial drug artemisinin. https://t.co/5vysOhstne
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Out now, we use bioinformatics+metabolomics to uncover a plant biosynthetic cassette responsible for diverse cyclic peptides. We apply this to find new NPs in Coffea. Finally, we reconstitute the first enzyme activity for a split BURP peptide cyclase! https://t.co/jkeiInMgRM
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A Widely Distributed #Biosynthetic Cassette Is Responsible for Diverse Plant Side Chain Cross-Linked Cyclopeptides by @stella_lima33, B Ampolini, @EthanU99, T Graf, C Earp, I Khedi, @mikepasquale77, Jonathan Chekan @ChekanLab at @uncg_chem in @angew_chem
https://t.co/zfFFU5P6jK
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Chekan Lab 2022 Holiday Potluck was a ton of fun! So lucky to be part of this awesome group of scientists!
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We have an opening for a NIH-funded postdoc in the lab! Our research focuses on the discovery and engineering of new RiPP natural product biosynthetic pathways using bioinformatic and in vitro approaches. See details below. #chempostdoc
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Congratulations to @ButlerKeelie for passing her PhD proposal defense! Keelie was the first graduate student to join the lab and it was awesome to see all of her successes!!
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Out now in @angew_chem, we highlight the awesome study by the @OConnor_lab to solve a longstanding question in the plant natural product community: biosynthesis of the infamous neurotoxin strychnine. Congrats to @sanathrajkk0 for putting this together! https://t.co/ozuIoJrHMn
onlinelibrary.wiley.com
Strychnine is a notorious neurotoxic plant alkaloid that has been studied for centuries. A recent report from the O'Connor group has successfully elucidated the biosynthesis of strychnine for the...
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Awesome day at the Zoo and then lunch with the lab+family! 🐻❄️ So lucky to be part of such a great group!
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It has been extremely exciting work with this project and biosynthesis in plants! Amazing challenge explore these incredible organisms and looking for cool biosynthetic enzymes! Enjoying a lot 🌿🌱🧬💚
Congrats to @stella_lima33 @EthanU99 Brigitte, Tyler, Cody, and Imani for all your hard work on this project!
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Pesquisadores mapeiam genes da guanitoxina, uma das mais letais neurotoxinas de água doce Resultados serão base para o desenvolvimento de novos testes de diagnóstico molecular para detecção da neurotoxina, já relatada em lagos e rios do Brasil e exterior https://t.co/W4IV07m3Zt
jornal.usp.br
Os resultados servirão de base para o desenvolvimento de novos testes de diagnóstico molecular para detecção da guanitoxina, já relatada em lagos e rios brasileiros e no exterior
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